Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients
Recently, a paper published in Science by Hadjadj et al. reported that type I interferon (IFN) deficiency, could be a hallmark of severe coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe COVID-19 was also associated with a lymphocytope...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14037
- Acceso en línea:
- https://doi.org/10.1038/s41392-020-00306-4
http://hdl.handle.net/20.500.12010/14037
- Palabra clave:
- I IFN deficiency
Immunological characteristic
COVID-19 patients
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Abierto (Texto Completo)
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Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients |
| title |
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients |
| spellingShingle |
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients I IFN deficiency Immunological characteristic COVID-19 patients Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| title_short |
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients |
| title_full |
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients |
| title_fullStr |
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients |
| title_full_unstemmed |
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients |
| title_sort |
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients |
| dc.subject.spa.fl_str_mv |
I IFN deficiency Immunological characteristic COVID-19 patients |
| topic |
I IFN deficiency Immunological characteristic COVID-19 patients Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| dc.subject.lemb.spa.fl_str_mv |
Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| description |
Recently, a paper published in Science by Hadjadj et al. reported that type I interferon (IFN) deficiency, could be a hallmark of severe coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe COVID-19 was also associated with a lymphocytopenia, persistent blood viral load, and an exacerbated inflammatory response (Fig. 1). These findings provide insights into the treatment of severe COVID-19 patients with type I IFN |
| publishDate |
2020 |
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2020-09-30T20:05:50Z |
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2020-09-30T20:05:50Z |
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2020 |
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Artículo |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.identifier.issn.spa.fl_str_mv |
2059-3635 |
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https://doi.org/10.1038/s41392-020-00306-4 |
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http://hdl.handle.net/20.500.12010/14037 |
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https://doi.org/10.1038/s41392-020-00306-4 |
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2059-3635 |
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https://doi.org/10.1038/s41392-020-00306-4 http://hdl.handle.net/20.500.12010/14037 |
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eng |
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eng |
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Abierto (Texto Completo) |
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Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
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2 páginas |
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| dc.publisher.spa.fl_str_mv |
Signal Transduction and Targeted Therapy |
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2020-09-30T20:05:50Z2020-09-30T20:05:50Z20202059-3635https://doi.org/10.1038/s41392-020-00306-4http://hdl.handle.net/20.500.12010/14037https://doi.org/10.1038/s41392-020-00306-4Recently, a paper published in Science by Hadjadj et al. reported that type I interferon (IFN) deficiency, could be a hallmark of severe coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe COVID-19 was also associated with a lymphocytopenia, persistent blood viral load, and an exacerbated inflammatory response (Fig. 1). These findings provide insights into the treatment of severe COVID-19 patients with type I IFN2 páginasapplication/pdfengSignal Transduction and Targeted Therapyreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoI IFN deficiencyImmunological characteristicCOVID-19 patientsSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusType I IFN deficiency: an immunological characteristic of severe COVID-19 patientsArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Wang, ZhenlingPan, HailongJiang, BoguangLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14037/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILs41392-020-00306-4.pdf.jpgs41392-020-00306-4.pdf.jpgIM Thumbnailimage/jpeg24698https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14037/3/s41392-020-00306-4.pdf.jpg4baa1b421008311cb4906a7aa867c9e8MD53open access20.500.12010/14037oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/140372021-03-17 19:51:42.066metadata only accessRepositorio Institucional - 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