Efficacy and safety of obinutuzumab in active lupus nephritis

Obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, provided sig nificantly better renal responses than placebo in a phase 2 trial involving patients with lupus nephritis receiving standard therapy. METHODS In a phase 3, randomized, controlled trial, we assigned adults with biopsy-prove...

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Autores:
Furie, R.A.
Rovin, B.H.
Garg, J.P.
Santiago, M.B.
Aroca Martínez, G.
Zuta Santillán, A.E.
Álvarez, D.
Navarro Sandoval, C.
Lila, A.M.
Tumlin, J.A.
Saxena, A.
Irazoque Palazuelos, F.
Raghu, H.
Yoo, B.
Hassan, I.
Martins, E.
Sehgal, H.
Kirchner, P.
Ross Terres, J.
Omachi, T.A.
Schindler, T.
Pendergraft, W.F.
Malvar, A.
Tipo de recurso:
Fecha de publicación:
2025
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
eng
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/16252
Acceso en línea:
https://hdl.handle.net/20.500.12442/16252
https://www.nejm.org/doi/full/10.1056/NEJMoa2410965
Palabra clave:
Rights
closedAccess
License
Attribution-NonCommercial-NoDerivs 3.0 United States