Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine

A new Rhodamine-based “Turn On” fluorescent probe (E)- 3′,6′-bis(diethylamino)-2-((2,5-dimethoxybenzylidene)amino)spiro[isoindoline-1,9′-xanthen]-3-one (WGB) was synthesized. Results show that WGB is selective for Cu2+ cations, forming a WGB-Cu2+ complex in a 2:1 stoichiometry, confirmed through den...

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Autores:: Zuzunaga Sanchez, Camilo Andres
Yañez, Osvaldo
Galdámez, Antonio
Tapia, Victoria
Núñez, Marco T
Osorio-Román, Igor
García, Camilo
García-Beltrán, Olimpo

Tipo de recurso:: Article of investigation

Fecha de publicación:: 2023

Institución:: Universidad de Ibagué

Repositorio:: Repositorio Universidad de Ibagué

Idioma:: eng

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network_acronym_str	UNIBAGUE2
network_name_str	Repositorio Universidad de Ibagué
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dc.title.eng.fl_str_mv	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine
title	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine
spellingShingle	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine Sonda colorimétrica - Características Sonda fluorométrica - Características Chemosensor Colorimetric fluorescent dye Cu2+ ions Rhodamine derivate Turn-On
title_short	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine
title_full	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine
title_fullStr	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine
title_full_unstemmed	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine
title_sort	Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine
dc.creator.fl_str_mv	Zuzunaga Sanchez, Camilo Andres Yañez, Osvaldo Galdámez, Antonio Tapia, Victoria Núñez, Marco T Osorio-Román, Igor García, Camilo García-Beltrán, Olimpo
dc.contributor.author.none.fl_str_mv	Zuzunaga Sanchez, Camilo Andres Yañez, Osvaldo Galdámez, Antonio Tapia, Victoria Núñez, Marco T Osorio-Román, Igor García, Camilo García-Beltrán, Olimpo
dc.subject.armarc.none.fl_str_mv	Sonda colorimétrica - Características Sonda fluorométrica - Características
topic	Sonda colorimétrica - Características Sonda fluorométrica - Características Chemosensor Colorimetric fluorescent dye Cu2+ ions Rhodamine derivate Turn-On
dc.subject.proposal.eng.fl_str_mv	Chemosensor Colorimetric fluorescent dye Cu2+ ions Rhodamine derivate Turn-On
description	A new Rhodamine-based “Turn On” fluorescent probe (E)- 3′,6′-bis(diethylamino)-2-((2,5-dimethoxybenzylidene)amino)spiro[isoindoline-1,9′-xanthen]-3-one (WGB) was synthesized. Results show that WGB is selective for Cu2+ cations, forming a WGB-Cu2+ complex in a 2:1 stoichiometry, confirmed through density functional theory (DFT) electronic structure calculations and reactive molecular dynamics (MD) simulations. Theoretical calculations agreed with the experimental data. The detection limit of WGB-Cu+2 complex is 6.76 × 10-8 M. Preliminary studies employing epifluorescence microscopy demonstrate that Cu2+ can be imaged in neuroblastoma SH-SY5Y cells treated with WGB.
publishDate	2023
dc.date.issued.none.fl_str_mv	2023-01-01
dc.date.accessioned.none.fl_str_mv	2025-09-01T21:08:15Z
dc.date.available.none.fl_str_mv	2025-09-01T21:08:15Z
dc.type.none.fl_str_mv	Artículo de revista
dc.type.coar.none.fl_str_mv	http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coarversion.none.fl_str_mv	http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.content.none.fl_str_mv	Text
dc.type.driver.none.fl_str_mv	info:eu-repo/semantics/article
dc.type.version.none.fl_str_mv	info:eu-repo/semantics/publishedVersion
format	http://purl.org/coar/resource_type/c_2df8fbb1
status_str	publishedVersion
dc.identifier.citation.none.fl_str_mv	Segura, C., Yañez, O., Galdámez, A., Tapia, V., Núñez, M., Osorio-Román, I., García, C. y García-Beltrán, O. (2023). Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine. Journal of Photochemistry and Photobiology A: Chemistry, 434. DOI: 10.1016/j.jphotochem.2022.114278
dc.identifier.doi.none.fl_str_mv	10.1016/j.jphotochem.2022.114278
dc.identifier.eissn.none.fl_str_mv	18732666
dc.identifier.issn.none.fl_str_mv	Journal of Photochemistry and Photobiology A: Chemistry
dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/20.500.12313/5581
dc.identifier.url.none.fl_str_mv	https://www.sciencedirect.com/science/article/pii/S1010603022005019
identifier_str_mv	Segura, C., Yañez, O., Galdámez, A., Tapia, V., Núñez, M., Osorio-Román, I., García, C. y García-Beltrán, O. (2023). Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine. Journal of Photochemistry and Photobiology A: Chemistry, 434. DOI: 10.1016/j.jphotochem.2022.114278 10.1016/j.jphotochem.2022.114278 18732666 Journal of Photochemistry and Photobiology A: Chemistry
url	https://hdl.handle.net/20.500.12313/5581 https://www.sciencedirect.com/science/article/pii/S1010603022005019
dc.language.iso.none.fl_str_mv	eng
language	eng
dc.relation.citationstartpage.none.fl_str_mv	114278
dc.relation.citationvolume.none.fl_str_mv	434
dc.relation.ispartofjournal.none.fl_str_mv	Journal of Photochemistry and Photobiology A: Chemistry
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spelling	Zuzunaga Sanchez, Camilo Andresd8e3ec65-da95-477d-a223-08020b5db4ef600Yañez, Osvaldo2cf4e584-65f4-4612-a255-91946983e93a-1Galdámez, Antonioa24c3944-06a6-4e80-b30f-f6180b21eb78-1Tapia, Victoria4a5e6fc1-b00f-4ff8-95ac-ecaa9f6fc2df-1Núñez, Marco T4b5cf28b-0047-4d6d-b693-86ab67af165f-1Osorio-Román, Igorc1772296-47dd-43b9-8f89-fd6eb665662b-1García, Camiloa242acd0-27fc-4f74-9edf-a79f4a8315af-1García-Beltrán, Olimpodfe2bbe7-81d5-415c-9be6-6469a5a40c75-12025-09-01T21:08:15Z2025-09-01T21:08:15Z2023-01-01A new Rhodamine-based “Turn On” fluorescent probe (E)- 3′,6′-bis(diethylamino)-2-((2,5-dimethoxybenzylidene)amino)spiro[isoindoline-1,9′-xanthen]-3-one (WGB) was synthesized. Results show that WGB is selective for Cu2+ cations, forming a WGB-Cu2+ complex in a 2:1 stoichiometry, confirmed through density functional theory (DFT) electronic structure calculations and reactive molecular dynamics (MD) simulations. Theoretical calculations agreed with the experimental data. The detection limit of WGB-Cu+2 complex is 6.76 × 10-8 M. Preliminary studies employing epifluorescence microscopy demonstrate that Cu2+ can be imaged in neuroblastoma SH-SY5Y cells treated with WGB.application/pdfSegura, C., Yañez, O., Galdámez, A., Tapia, V., Núñez, M., Osorio-Román, I., García, C. y García-Beltrán, O. (2023). Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine. Journal of Photochemistry and Photobiology A: Chemistry, 434. DOI: 10.1016/j.jphotochem.2022.11427810.1016/j.jphotochem.2022.11427818732666Journal of Photochemistry and Photobiology A: Chemistryhttps://hdl.handle.net/20.500.12313/5581https://www.sciencedirect.com/science/article/pii/S1010603022005019engElsevier B.V.Países bajos114278434Journal of Photochemistry and Photobiology A: ChemistryQ. Zhang, R. Ma, Z. Li, Z. 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Zhurko, Chemcraft - graphical software for visualization of quantum chemistry computations., (2018).© 2022 The Author(s)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/https://www.sciencedirect.com/science/article/pii/S1010603022005019Sonda colorimétrica - CaracterísticasSonda fluorométrica - CaracterísticasChemosensorColorimetric fluorescent dyeCu2+ ionsRhodamine derivateTurn-OnSynthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamineArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Textinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPublicationORIGINALArtículo.pdfArtículo.pdfapplication/pdf292556https://repositorio.unibague.edu.co/bitstreams/1ea2f870-1fa7-45a2-ba7b-2447ca0fe74b/download3b8e783c195413502568d981f06481a9MD52TEXTArtículo.pdf.txtArtículo.pdf.txtExtracted texttext/plain5177https://repositorio.unibague.edu.co/bitstreams/cb613432-eb43-426e-97b9-270be3d3c8e1/download50404f3e2a2d875084db2b7a2f8d2f6dMD53THUMBNAILArtículo.pdf.jpgArtículo.pdf.jpgIM Thumbnailimage/jpeg31425https://repositorio.unibague.edu.co/bitstreams/c71c25ea-0852-472f-a91b-fbceaeebe7b3/downloada16c785842f3fe3de4785089e5e4ae95MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-8134https://repositorio.unibague.edu.co/bitstreams/a3d76940-1545-4b03-b953-e586bfa17d74/download2fa3e590786b9c0f3ceba1b9656b7ac3MD5120.500.12313/5581oai:repositorio.unibague.edu.co:20.500.12313/55812025-09-12 12:22:12.529https://creativecommons.org/licenses/by-nc/4.0/© 2022 The Author(s)https://repositorio.unibague.edu.coRepositorio Institucional Universidad de Ibaguébdigital@metabiblioteca.comQ3JlYXRpdmUgQ29tbW9ucyBBdHRyaWJ1dGlvbi1Ob25Db21tZXJjaWFsLU5vRGVyaXZhdGl2ZXMgNC4wIEludGVybmF0aW9uYWwgTGljZW5zZQ0KaHR0cHM6Ly9jcmVhdGl2ZWNvbW1vbnMub3JnL2xpY2Vuc2VzL2J5LW5jLW5kLzQuMC8=

Synthesis and characterization of a novel colorimetric and fluorometric probe “Turn-on” for the detection of Cu2+ of derivatives rhodamine

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