In vitro and in silico analysis of galanthine from Zephyranthes carinata as an inhibitor of acetylcholinesterase

Zephyranthes carinata Herb., a specie of the Amaryllidoideae subfamily, has been reported to have inhibitory activity against acetylcholinesterase. However, scientific evidence related to their bioactive alkaloids has been lacking. Thus, this study describes the isolation of the alkaloids of this pl...

Full description

Autores:

Sierra, Karina
De Andrade, Jean Paulo
Angel Villalba, Javier R
Osorio, Edison
Yañéz, Osvaldo
Guaita Martínez, José Manuel
Oleas, Nora H.
García-Beltrán, Olimpo
De S. Borges, Warley
Bastida, Jaume
Osorio, Edison
Cortes, Natalie

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Ibagué

Repositorio:

Repositorio Universidad de Ibagué

Idioma:

eng

OAI Identifier:

oai:repositorio.unibague.edu.co:20.500.12313/5488

Acceso en línea:

https://www.sciencedirect.com/science/article/pii/S075333222200405X

Palabra clave:

Alcaloides de Amaryllidaceae Galantina
Acetylcholinesterase inhibition
Amaryllidaceae alkaloids
Galanthine; Molecular docking
Molecular dynamics

Rights

openAccess

License

http://purl.org/coar/access_right/c_abf2