Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia

Antecedentes: Este estudio explora las diferencias clínicas y angiográficas en adultos jóvenes (≤50 años) con infarto agudo de miocardio (IAM), comparándolos con pacientes de mayor edad y analizando diferencias según el sexo. Materiales y Métodos: Se realizó un estudio de cohorte retrospectivo con 4...

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Autores:
Ramirez Yañez, Hernan
Figueroa Triana, Juan
Buitrago Sandoval, Andres
Arias Beltrán, Jose
Tipo de recurso:
https://purl.org/coar/resource_type/c_7a1f
Fecha de publicación:
2025
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/15005
Acceso en línea:
https://hdl.handle.net/20.500.12495/15005
Palabra clave:
Infarto agudo de miocardio
síndrome coronario agudo
adultos jóvenes
mujeres
angiografía coronaria
Acute myocardial infarction
acute coronary syndrome
young adults
women
coronary angiography
WB 115
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License
Attribution-NonCommercial-ShareAlike 4.0 International
id UNBOSQUE2_de426ac302924ed733f0f81b1c908d88
oai_identifier_str oai:repositorio.unbosque.edu.co:20.500.12495/15005
network_acronym_str UNBOSQUE2
network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.none.fl_str_mv Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
dc.title.translated.none.fl_str_mv Acute myocardial infarction in young adults at a university hospital in Bogotá, Colombia
title Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
spellingShingle Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
Infarto agudo de miocardio
síndrome coronario agudo
adultos jóvenes
mujeres
angiografía coronaria
Acute myocardial infarction
acute coronary syndrome
young adults
women
coronary angiography
WB 115
title_short Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
title_full Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
title_fullStr Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
title_full_unstemmed Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
title_sort Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá Colombia
dc.creator.fl_str_mv Ramirez Yañez, Hernan
Figueroa Triana, Juan
Buitrago Sandoval, Andres
Arias Beltrán, Jose
dc.contributor.advisor.none.fl_str_mv Figueroa Triana, Juan
dc.contributor.author.none.fl_str_mv Ramirez Yañez, Hernan
Figueroa Triana, Juan
Buitrago Sandoval, Andres
Arias Beltrán, Jose
dc.contributor.orcid.none.fl_str_mv 0000-0002-7939-3630
0000-0002-7239-8260
0000-0001-7693-0771
0000-0003-3919-2137
dc.subject.none.fl_str_mv Infarto agudo de miocardio
síndrome coronario agudo
adultos jóvenes
mujeres
angiografía coronaria
topic Infarto agudo de miocardio
síndrome coronario agudo
adultos jóvenes
mujeres
angiografía coronaria
Acute myocardial infarction
acute coronary syndrome
young adults
women
coronary angiography
WB 115
dc.subject.keywords.none.fl_str_mv Acute myocardial infarction
acute coronary syndrome
young adults
women
coronary angiography
dc.subject.nlm.none.fl_str_mv WB 115
description Antecedentes: Este estudio explora las diferencias clínicas y angiográficas en adultos jóvenes (≤50 años) con infarto agudo de miocardio (IAM), comparándolos con pacientes de mayor edad y analizando diferencias según el sexo. Materiales y Métodos: Se realizó un estudio de cohorte retrospectivo con 455 pacientes con diagnóstico de IAM entre noviembre de 2019 y junio de 2023. Se analizaron factores de riesgo, hallazgos angiográficos coronarios y desenlaces clínicos según edad y sexo, utilizando análisis univariado, bivariado y regresión logística. Resultados: Del total de pacientes, el 12% tenía ≤50 años y el 23% eran mujeres. Los pacientes jóvenes fueron predominantemente hombres (OR 5.51) y presentaron mayor peso corporal, colesterol total, colesterol LDL y triglicéridos (p < 0.01). Los pacientes mayores mostraron mayor prevalencia de hipertensión, enfermedad coronaria previa, dislipidemia e hipotiroidismo (p < 0.01). Las mujeres presentaron tasas más altas de hipertensión (OR 1.93), hipotiroidismo (OR 2.9) y sedentarismo (OR 1.69), mientras que los hombres presentaron mayores tasas de tabaquismo (OR 2.23) y consumo de alcohol (OR 4.03). El IAM con elevación del ST (STEMI) fue más común en hombres (OR 1.58). Los pacientes jóvenes presentaron mayores tasas de ectasia coronaria (OR 3.8), oclusión trombótica (OR 3.8) y MINOCA (IAM sin obstrucción coronaria significativa) (OR 2.9), siendo MINOCA más común en mujeres (OR 1.8). Las mujeres también tuvieron tiempos más prolongados entre la llegada al hospital y la angioplastia (puerta-balón) (OR 2.8). Conclusión: Los adultos jóvenes con IAM presentan menos factores de riesgo tradicionales, pero una mayor prevalencia de ectasia coronaria, MINOCA y oclusión trombótica. Existen diferencias marcadas según el sexo, lo que resalta la importancia de enfoques específicos por edad y sexo en la evaluación y el manejo del IAM.
publishDate 2025
dc.date.accessioned.none.fl_str_mv 2025-07-21T16:24:45Z
dc.date.available.none.fl_str_mv 2025-07-21T16:24:45Z
dc.date.issued.none.fl_str_mv 2025-06
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.local.spa.fl_str_mv Tesis/Trabajo de grado - Monografía - Especialización
dc.type.coar.none.fl_str_mv https://purl.org/coar/resource_type/c_7a1f
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/bachelorThesis
dc.type.coarversion.none.fl_str_mv https://purl.org/coar/version/c_ab4af688f83e57aa
format https://purl.org/coar/resource_type/c_7a1f
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12495/15005
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv repourl:https://repositorio.unbosque.edu.co
url https://hdl.handle.net/20.500.12495/15005
identifier_str_mv instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
repourl:https://repositorio.unbosque.edu.co
dc.language.iso.fl_str_mv eng
language eng
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spelling Figueroa Triana, JuanRamirez Yañez, HernanFigueroa Triana, JuanBuitrago Sandoval, AndresArias Beltrán, Jose0000-0002-7939-36300000-0002-7239-82600000-0001-7693-07710000-0003-3919-21372025-07-21T16:24:45Z2025-07-21T16:24:45Z2025-06https://hdl.handle.net/20.500.12495/15005instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coAntecedentes: Este estudio explora las diferencias clínicas y angiográficas en adultos jóvenes (≤50 años) con infarto agudo de miocardio (IAM), comparándolos con pacientes de mayor edad y analizando diferencias según el sexo. Materiales y Métodos: Se realizó un estudio de cohorte retrospectivo con 455 pacientes con diagnóstico de IAM entre noviembre de 2019 y junio de 2023. Se analizaron factores de riesgo, hallazgos angiográficos coronarios y desenlaces clínicos según edad y sexo, utilizando análisis univariado, bivariado y regresión logística. Resultados: Del total de pacientes, el 12% tenía ≤50 años y el 23% eran mujeres. Los pacientes jóvenes fueron predominantemente hombres (OR 5.51) y presentaron mayor peso corporal, colesterol total, colesterol LDL y triglicéridos (p < 0.01). Los pacientes mayores mostraron mayor prevalencia de hipertensión, enfermedad coronaria previa, dislipidemia e hipotiroidismo (p < 0.01). Las mujeres presentaron tasas más altas de hipertensión (OR 1.93), hipotiroidismo (OR 2.9) y sedentarismo (OR 1.69), mientras que los hombres presentaron mayores tasas de tabaquismo (OR 2.23) y consumo de alcohol (OR 4.03). El IAM con elevación del ST (STEMI) fue más común en hombres (OR 1.58). Los pacientes jóvenes presentaron mayores tasas de ectasia coronaria (OR 3.8), oclusión trombótica (OR 3.8) y MINOCA (IAM sin obstrucción coronaria significativa) (OR 2.9), siendo MINOCA más común en mujeres (OR 1.8). Las mujeres también tuvieron tiempos más prolongados entre la llegada al hospital y la angioplastia (puerta-balón) (OR 2.8). Conclusión: Los adultos jóvenes con IAM presentan menos factores de riesgo tradicionales, pero una mayor prevalencia de ectasia coronaria, MINOCA y oclusión trombótica. Existen diferencias marcadas según el sexo, lo que resalta la importancia de enfoques específicos por edad y sexo en la evaluación y el manejo del IAM.Fundación Santa Fe de BogotaEspecialista en Medicina InternaEspecializaciónBackground: This study explores the clinical and angiographic differences in young adults (≤50 years) with acute myocardial infarction (AMI), comparing them to older patients and analyzing sex-based differences. Materials and Methods: A retrospective cohort study was conducted with 455 AMI patients diagnosed between November 2019 and June 2023. Risk factors, coronary angiographic findings, and clinical outcomes were analyzed by age and sex using univariate, bivariate, and logistic regression analyses.Results: Of the total patients, 12% were ≤50 years old, and 23% were women. Young patients were predominantly male (OR 5.51) and had higher body weight, total cholesterol, LDL cholesterol, and triglycerides (p < 0.01). Older patients had a higher prevalence of hypertension, prior coronary artery disease, dyslipidemia, and hypothyroidism (p < 0.01). Women had higher rates of hypertension (OR 1.93), hypothyroidism (OR 2.9), and sedentary lifestyle (OR 1.69), while men had higher rates of smoking (OR 2.23) and alcohol consumption (OR 4.03). STEMI was more common in men (OR 1.58). Young patients had higher rates of coronary ectasia (OR 3.8), thrombotic occlusion (OR 3.8), and MINOCA (OR 2.9), with MINOCA more common in women (OR 1.8). Women also had longer door-to-balloon times (OR 2.8). Conclusion: Young adults with AMI present fewer traditional risk factors but a higher prevalence of coronary ectasia, MINOCA, and thrombotic occlusion. There are marked sex-related differences, emphasizing the importance of age- and sex-specific approaches in AMI evaluation and management.application/pdfAttribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/Acceso abiertohttps://purl.org/coar/access_right/c_abf2http://purl.org/coar/access_right/c_abf2Infarto agudo de miocardiosíndrome coronario agudoadultos jóvenesmujeresangiografía coronariaAcute myocardial infarctionacute coronary syndromeyoung adultswomencoronary angiographyWB 115Infarto agudo de miocardio en adultos jóvenes en un hospital universitario de Bogotá ColombiaAcute myocardial infarction in young adults at a university hospital in Bogotá, ColombiaEspecialización en Medicina InternaUniversidad El BosqueFacultad de MedicinaTesis/Trabajo de grado - Monografía - Especializaciónhttps://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesishttps://purl.org/coar/version/c_ab4af688f83e57aa1. 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