Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos

El uso de métodos anticonceptivos ha presentado problemas de adherencia y aceptabilidad en Colombia y el mundo. Distintos estudios de la OMS indican que las mujeres aún cuando desean evitar el embarazo dejan de usar estos métodos debido a los efectos secundarios que presentan. La industria fármacéut...

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Autores:
Reina López, Laura Camila
Rodríguez Tavera, Ricardo Andrés
Tipo de recurso:
https://purl.org/coar/resource_type/c_7a1f
Fecha de publicación:
2024
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
spa
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/14370
Acceso en línea:
https://hdl.handle.net/20.500.12495/14370
Palabra clave:
Parches transdérmicos de microagujas
Liberación controlada
Microagujas biodegradables
Levonorgestrel
Aceptabilidad
Adherencia
615.19
Transdermal microneedle patches
Controlled release
Biodegradable microneedles
Levonorgestrel
Acceptability
Adherence
Rights
License
Attribution-NonCommercial-NoDerivatives 4.0 International
id UNBOSQUE2_a2ed1cd856af053b916de5b06bccaf8b
oai_identifier_str oai:repositorio.unbosque.edu.co:20.500.12495/14370
network_acronym_str UNBOSQUE2
network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.none.fl_str_mv Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
dc.title.translated.none.fl_str_mv Literature review: Transdermal microneedle patches transdermal microneedle patches for contraceptive drug delivery
title Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
spellingShingle Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
Parches transdérmicos de microagujas
Liberación controlada
Microagujas biodegradables
Levonorgestrel
Aceptabilidad
Adherencia
615.19
Transdermal microneedle patches
Controlled release
Biodegradable microneedles
Levonorgestrel
Acceptability
Adherence
title_short Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
title_full Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
title_fullStr Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
title_full_unstemmed Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
title_sort Revisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivos
dc.creator.fl_str_mv Reina López, Laura Camila
Rodríguez Tavera, Ricardo Andrés
dc.contributor.advisor.none.fl_str_mv Velandia Paris, María Angélica
dc.contributor.author.none.fl_str_mv Reina López, Laura Camila
Rodríguez Tavera, Ricardo Andrés
dc.subject.none.fl_str_mv Parches transdérmicos de microagujas
Liberación controlada
Microagujas biodegradables
Levonorgestrel
Aceptabilidad
Adherencia
topic Parches transdérmicos de microagujas
Liberación controlada
Microagujas biodegradables
Levonorgestrel
Aceptabilidad
Adherencia
615.19
Transdermal microneedle patches
Controlled release
Biodegradable microneedles
Levonorgestrel
Acceptability
Adherence
dc.subject.ddc.none.fl_str_mv 615.19
dc.subject.keywords.none.fl_str_mv Transdermal microneedle patches
Controlled release
Biodegradable microneedles
Levonorgestrel
Acceptability
Adherence
description El uso de métodos anticonceptivos ha presentado problemas de adherencia y aceptabilidad en Colombia y el mundo. Distintos estudios de la OMS indican que las mujeres aún cuando desean evitar el embarazo dejan de usar estos métodos debido a los efectos secundarios que presentan. La industria fármacéutica ha explorado diversos métodos anticonceptivos, en donde se han incluido los parches transdérmicos de microagujas como una alternativa con menos efectos secundarios y mayor adherencia al tratamiento. Se realizó una revisión bibliográfica utilizando la metodología PRISMA, donde se emplearon criterios de inclusión y exclusión, allí se analizaron 50 artículos con el fin de dar cumplimiento a los objetivos planteados. Se determinó que los parches transdérmicos de microagujas ofrecen ventajas significativas como una liberación controlada de fármacos. Los diferentes tipos de microagujas (sólidas, recubiertas, biodegradables, huecas y de hidrogel), demostraron diferencias en eficacia y caracteristicas de liberación. Las microagujas biodegradables permiten una liberación controlada de Levonorgestrel de hasta 45 días sin dejar ningún residuo biopeligroso, lo que convierte a los parches transdérmicos de microagujas en una opción innovadora y viable para la administración de Levonorgestrel debido a que facilita la entrega, siendo más eficiente y controlada, permitiendo mayor adherencia y aceptabilidad por los pacientes.
publishDate 2024
dc.date.issued.none.fl_str_mv 2024-10
dc.date.accessioned.none.fl_str_mv 2025-05-16T16:33:48Z
dc.date.available.none.fl_str_mv 2025-05-16T16:33:48Z
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.local.none.fl_str_mv Tesis/Trabajo de grado - Monografía - Pregrado
dc.type.coar.none.fl_str_mv https://purl.org/coar/resource_type/c_7a1f
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/bachelorThesis
dc.type.coarversion.none.fl_str_mv https://purl.org/coar/version/c_ab4af688f83e57aa
format https://purl.org/coar/resource_type/c_7a1f
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12495/14370
dc.identifier.instname.spa.fl_str_mv Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv repourl:https://repositorio.unbosque.edu.co
url https://hdl.handle.net/20.500.12495/14370
identifier_str_mv Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
repourl:https://repositorio.unbosque.edu.co
dc.language.iso.fl_str_mv spa
language spa
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spelling Velandia Paris, María AngélicaReina López, Laura CamilaRodríguez Tavera, Ricardo Andrés2025-05-16T16:33:48Z2025-05-16T16:33:48Z2024-10https://hdl.handle.net/20.500.12495/14370Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coEl uso de métodos anticonceptivos ha presentado problemas de adherencia y aceptabilidad en Colombia y el mundo. Distintos estudios de la OMS indican que las mujeres aún cuando desean evitar el embarazo dejan de usar estos métodos debido a los efectos secundarios que presentan. La industria fármacéutica ha explorado diversos métodos anticonceptivos, en donde se han incluido los parches transdérmicos de microagujas como una alternativa con menos efectos secundarios y mayor adherencia al tratamiento. Se realizó una revisión bibliográfica utilizando la metodología PRISMA, donde se emplearon criterios de inclusión y exclusión, allí se analizaron 50 artículos con el fin de dar cumplimiento a los objetivos planteados. Se determinó que los parches transdérmicos de microagujas ofrecen ventajas significativas como una liberación controlada de fármacos. Los diferentes tipos de microagujas (sólidas, recubiertas, biodegradables, huecas y de hidrogel), demostraron diferencias en eficacia y caracteristicas de liberación. Las microagujas biodegradables permiten una liberación controlada de Levonorgestrel de hasta 45 días sin dejar ningún residuo biopeligroso, lo que convierte a los parches transdérmicos de microagujas en una opción innovadora y viable para la administración de Levonorgestrel debido a que facilita la entrega, siendo más eficiente y controlada, permitiendo mayor adherencia y aceptabilidad por los pacientes.PregradoQuímico FarmacéuticoThe use of contraceptive methods has presented problems of adherence and acceptability in Colombia and the world. Different WHO studies indicate that even when women want to avoid pregnancy, they stop using these methods due to the side effects they present. The pharmaceutical industry has explored various contraceptive methods, where transdermal microneedle patches have been included as an alternative with fewer side effects and greater adherence to treatment. A bibliographic review was carried out using the PRISMA methodology, where inclusion and exclusion criteria were used, and 50 articles were analyzed in order to fulfill the objectives. It was determined that transdermal microneedle patches offer significant advantages such as controlled drug release. The different types of microneedles (solid, coated, biodegradable, hollow and hydrogel) showed differences in efficacy and release characteristics. Biodegradable microneedles allow a controlled release of Levonorgestrel for up to 45 days without leaving any biohazardous residue, which makes transdermal microneedle patches an innovative and viable option for Levonorgestrel administration because it facilitates delivery, being more efficient and controlled, allowing greater adherence and acceptability by patients.application/pdfAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Acceso abiertohttps://purl.org/coar/access_right/c_abf2http://purl.org/coar/access_right/c_abf2Parches transdérmicos de microagujasLiberación controladaMicroagujas biodegradablesLevonorgestrelAceptabilidadAdherencia615.19Transdermal microneedle patchesControlled releaseBiodegradable microneedlesLevonorgestrelAcceptabilityAdherenceRevisión bibliográfica: Parches transdérmicos de microagujas para la administración de fármacos anticonceptivosLiterature review: Transdermal microneedle patches transdermal microneedle patches for contraceptive drug deliveryQuímica FarmacéuticaUniversidad El BosqueFacultad de CienciasTesis/Trabajo de grado - Monografía - Pregradohttps://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesishttps://purl.org/coar/version/c_ab4af688f83e57aa1. 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