Uso de PET SCAN en el estudio de la fiebre de origen desconocido, en una IPS de alta complejidad en Bogotá DC, Colombia

Fever of unknown origin (FUO) remains a frequent diagnostic challenge in clinical practice, particularly in high-complexity settings. Despite advances in diagnostic methodologies, a significant proportion of patients remain without a clear etiological diagnosis, delaying timely therapeutic intervent...

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Autores:: Centeno Padilla, Maria Jose
Montenegro Charry, Adolfo Alejandro

Tipo de recurso:: https://purl.org/coar/resource_type/c_7a1f

Fecha de publicación:: 2025

Institución:: Universidad El Bosque

Repositorio:: Repositorio U. El Bosque

Idioma:: spa

Description
Summary:	Fever of unknown origin (FUO) remains a frequent diagnostic challenge in clinical practice, particularly in high-complexity settings. Despite advances in diagnostic methodologies, a significant proportion of patients remain without a clear etiological diagnosis, delaying timely therapeutic interventions. The 18F-FDG-PET/CT has emerged as a valuable tool for identifying infectious, inflammatory, or neoplastic foci in these cases. However, its performance in the Colombian population has not been widely documented. A retrospective descriptive study was conducted to assess the utility of 18F-FDG-PET/CT in the diagnostic approach to patients with FUO hospitalized at a tertiary care institution in Bogotá, Colombia, between 2019 and 2023. A total of 38 patients were included, and clinical, laboratory, and imaging data were collected. Descriptive statistical analysis was performed, including frequencies, percentages, medians, and interquartile ranges. In 84.2% of cases, 18F-FDG-PET/CT contributed to guiding the diagnosis or identifying a probable underlying cause. In 28 patients (73.68%), the PET/CT findings were concordant with other diagnostic tests and the final diagnosis. In 16 cases (42.10%), PET/CT findings led to changes in clinical management or prompted additional targeted investigations. In conclusion, 18F-FDG-PET/CT proved to be a highly useful diagnostic tool in the evaluation of patients with FUO, particularly in those with inconclusive initial workups.

Uso de PET SCAN en el estudio de la fiebre de origen desconocido, en una IPS de alta complejidad en Bogotá DC, Colombia

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