Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide

En varios estudios se ha identificado una conexión significativa entre la artritis reumatoide (AR) y la depresión, dado el alto índice de depresión registrado entre los pacientes con AR. La evidencia creciente sugiere que la AR puede ser un factor de riesgo para el desarrollo de depresión, y los pac...

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Autores:
Rodríguez Velandia, Yhojan Alexis
Tipo de recurso:
https://purl.org/coar/resource_type/c_7a1f
Fecha de publicación:
2025
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
spa
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/15545
Acceso en línea:
https://hdl.handle.net/20.500.12495/15545
Palabra clave:
Artritis reumatoide
Depresión
Actividad de la enfermedad
Rheumatoid arthritis
Depression
Disease activity
WB 115
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License
Attribution-NonCommercial-ShareAlike 4.0 International
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network_acronym_str UNBOSQUE2
network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.none.fl_str_mv Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
dc.title.translated.none.fl_str_mv Disease activity and depression in a colombian cohort with rheumatoid arthritis
title Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
spellingShingle Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
Artritis reumatoide
Depresión
Actividad de la enfermedad
Rheumatoid arthritis
Depression
Disease activity
WB 115
title_short Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
title_full Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
title_fullStr Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
title_full_unstemmed Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
title_sort Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoide
dc.creator.fl_str_mv Rodríguez Velandia, Yhojan Alexis
dc.contributor.advisor.none.fl_str_mv Quintana López, Gerardo
dc.contributor.author.none.fl_str_mv Rodríguez Velandia, Yhojan Alexis
dc.contributor.orcid.none.fl_str_mv Rodríguez Yhojan [0000-0002-0956-1491]
dc.subject.none.fl_str_mv Artritis reumatoide
Depresión
Actividad de la enfermedad
topic Artritis reumatoide
Depresión
Actividad de la enfermedad
Rheumatoid arthritis
Depression
Disease activity
WB 115
dc.subject.keywords.none.fl_str_mv Rheumatoid arthritis
Depression
Disease activity
dc.subject.nlm.none.fl_str_mv WB 115
description En varios estudios se ha identificado una conexión significativa entre la artritis reumatoide (AR) y la depresión, dado el alto índice de depresión registrado entre los pacientes con AR. La evidencia creciente sugiere que la AR puede ser un factor de riesgo para el desarrollo de depresión, y los pacientes que presentan ambas condiciones tienden a tener resultados clínicos menos favorables. No obstante, en Colombia, no se dispone de estimaciones precisas sobre la prevalencia de depresión en individuos con AR, y los estudios existentes enfrentan diversas limitaciones metodológicas. Este estudio se propone investigar la magnitud del problema de la depresión en pacientes con AR mediante la estimación de su prevalencia en una cohorte colombiana. Además, analizará cómo los síntomas depresivos influyen en la actividad de la enfermedad, al tiempo que identificará los factores que afectan la relación entre ambas enfermedades a lo largo del tiempo.
publishDate 2025
dc.date.accessioned.none.fl_str_mv 2025-07-29T14:20:11Z
dc.date.available.none.fl_str_mv 2025-07-29T14:20:11Z
dc.date.issued.none.fl_str_mv 2025-07
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.local.spa.fl_str_mv Tesis/Trabajo de grado - Monografía - Especialización
dc.type.coar.none.fl_str_mv https://purl.org/coar/resource_type/c_7a1f
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/bachelorThesis
dc.type.coarversion.none.fl_str_mv https://purl.org/coar/version/c_ab4af688f83e57aa
format https://purl.org/coar/resource_type/c_7a1f
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12495/15545
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv repourl:https://repositorio.unbosque.edu.co
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identifier_str_mv instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
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dc.language.iso.fl_str_mv spa
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dc.relation.references.none.fl_str_mv 1. Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet (London, England). Oktober 2016;388(10055):2023–38.
2. Ionescu C-E, Popescu CC, Agache M, Dinache G, Codreanu C. Depression in Rheumatoid Arthritis: Prevalence and Effects on Disease Activity. J Clin Med. April 2024;13(7).
3. ElSherbiny DA, ElSayed Saad W. Depression in rheumatoid arthritis patients: Screening for a frequent yet underestimated comorbidity. Egypt Rheumatol [Internet]. 2020;42(2):89–93. Available at: https://www.sciencedirect.com/science/article/pii/S1110116419300882
4. Strand V, Boklage SH, Kimura T, Joly F, Boyapati A, Msihid J. High levels of interleukin-6 in patients with rheumatoid arthritis are associated with greater improvements in health-related quality of life for sarilumab compared with adalimumab. Arthritis Res Ther. Oktober 2020;22(1):250.
5. Maldonado G, Ríos C, Paredes C, Ferro C, Intriago MJ, Aguirre C, et al. Depression in Rheumatoid Arthritis. Rev Colomb Reumatol (English Ed [Internet]. 2017;24(2):84–91. Available at: https://www.elsevier.es/es
6. Cui L, Li S, Wang S, Wu X, Liu Y, Yu W, et al. Major depressive disorder: hypothesis, mechanism, prevention and treatment. Signal Transduct Target Ther. Februarie 2024;9(1):30.
7. Fernández-Ávila DG, Rincón-Riaño DN, Bernal-Macías S, Gutiérrez Dávila JM, Rosselli D. Prevalencia de la artritis reumatoide en Colombia según información del Sistema Integral de Información de la Protección Social . Vol 26, Revista Colombiana de Reumatología . scieloco ; 2019. bl 83–7.
8. Anderson JK, Zimmerman L, Caplan L, Michaud K. Measures of rheumatoid arthritis disease activity: Patient (PtGA) and Provider (PrGA) Global Assessment of Disease Activity, Disease Activity Score (DAS) and Disease Activity Score with 28-Joint Counts (DAS28), Simplified Disease Activity Index (SDAI), C. Arthritis Care Res (Hoboken). November 2011;63 Suppl 1:S14-36.
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49. Gaujoux-Viala C, Mouterde G, Baillet A, Claudepierre P, Fautrel B, Le Loët X, et al. Evaluating disease activity in rheumatoid arthritis: Which composite index is best? A systematic literature analysis of studies comparing the psychometric properties of the DAS, DAS28, SDAI and CDAI. Jt Bone Spine [Internet]. 2012;79(2):149–55. Available at: https://www.sciencedirect.com/science/article/pii/S1297319X11001072
50. Rathbun AM, England BR, Mikuls TR, Ryan AS, Barton JL, Shardell MD, et al. Relationship Between Depression and Disease Activity in United States Veterans With Early Rheumatoid Arthritis Receiving Methotrexate. J Rheumatol. Junie 2021;48(6):813–20.
51. Pincus T, Sokka T. Quantitative measures for assessing rheumatoid arthritis in clinical trials and clinical care. Best Pract Res Clin Rheumatol [Internet]. 2003;17(5):753–81. Available at: https://www.sciencedirect.com/science/article/pii/S1521694203000779
52. Smolen JS, Landewé R, Breedveld FC, Dougados M, Emery P, Gaujoux-Viala C, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis. Junie 2010;69(6):964–75.
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spelling Quintana López, GerardoRodríguez Velandia, Yhojan AlexisRodríguez Yhojan [0000-0002-0956-1491]2025-07-29T14:20:11Z2025-07-29T14:20:11Z2025-07https://hdl.handle.net/20.500.12495/15545instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coEn varios estudios se ha identificado una conexión significativa entre la artritis reumatoide (AR) y la depresión, dado el alto índice de depresión registrado entre los pacientes con AR. La evidencia creciente sugiere que la AR puede ser un factor de riesgo para el desarrollo de depresión, y los pacientes que presentan ambas condiciones tienden a tener resultados clínicos menos favorables. No obstante, en Colombia, no se dispone de estimaciones precisas sobre la prevalencia de depresión en individuos con AR, y los estudios existentes enfrentan diversas limitaciones metodológicas. Este estudio se propone investigar la magnitud del problema de la depresión en pacientes con AR mediante la estimación de su prevalencia en una cohorte colombiana. Además, analizará cómo los síntomas depresivos influyen en la actividad de la enfermedad, al tiempo que identificará los factores que afectan la relación entre ambas enfermedades a lo largo del tiempo.Fundación Santa Fe de BogotáEspecialista en Medicina InternaEspecializaciónIn multiple studies, a significant connection has been identified between rheumatoid arthritis (RA) and depression, given the high rate of depression recorded among RA patients. Growing evidence suggests that RA may be a risk factor for developing depression, and patients with both conditions tend to have less favourable clinical outcomes. However, in Colombia, precise estimates of the prevalence of depression in individuals with RA are not available, and existing studies face various methodological limitations. This study aims to investigate the magnitude of the depression problem in RA patients by estimating its prevalence in a Colombian cohort. Additionally, it will analyse how depressive symptoms influence disease activity while identifying factors affecting the relationship between these two diseases over time.application/pdfAttribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/Acceso abiertohttps://purl.org/coar/access_right/c_abf2http://purl.org/coar/access_right/c_abf2Artritis reumatoideDepresiónActividad de la enfermedadRheumatoid arthritisDepressionDisease activityWB 115Actividad de la enfermedad y depresión en una cohorte colombiana con artritis reumatoideDisease activity and depression in a colombian cohort with rheumatoid arthritisEspecialización en Medicina InternaUniversidad El BosqueFacultad de MedicinaTesis/Trabajo de grado - Monografía - Especializaciónhttps://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesishttps://purl.org/coar/version/c_ab4af688f83e57aa1. Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet (London, England). Oktober 2016;388(10055):2023–38.2. Ionescu C-E, Popescu CC, Agache M, Dinache G, Codreanu C. Depression in Rheumatoid Arthritis: Prevalence and Effects on Disease Activity. J Clin Med. April 2024;13(7).3. ElSherbiny DA, ElSayed Saad W. Depression in rheumatoid arthritis patients: Screening for a frequent yet underestimated comorbidity. Egypt Rheumatol [Internet]. 2020;42(2):89–93. Available at: https://www.sciencedirect.com/science/article/pii/S11101164193008824. Strand V, Boklage SH, Kimura T, Joly F, Boyapati A, Msihid J. High levels of interleukin-6 in patients with rheumatoid arthritis are associated with greater improvements in health-related quality of life for sarilumab compared with adalimumab. Arthritis Res Ther. Oktober 2020;22(1):250.5. Maldonado G, Ríos C, Paredes C, Ferro C, Intriago MJ, Aguirre C, et al. Depression in Rheumatoid Arthritis. Rev Colomb Reumatol (English Ed [Internet]. 2017;24(2):84–91. Available at: https://www.elsevier.es/es6. Cui L, Li S, Wang S, Wu X, Liu Y, Yu W, et al. Major depressive disorder: hypothesis, mechanism, prevention and treatment. Signal Transduct Target Ther. Februarie 2024;9(1):30.7. Fernández-Ávila DG, Rincón-Riaño DN, Bernal-Macías S, Gutiérrez Dávila JM, Rosselli D. Prevalencia de la artritis reumatoide en Colombia según información del Sistema Integral de Información de la Protección Social . Vol 26, Revista Colombiana de Reumatología . scieloco ; 2019. bl 83–7.8. Anderson JK, Zimmerman L, Caplan L, Michaud K. Measures of rheumatoid arthritis disease activity: Patient (PtGA) and Provider (PrGA) Global Assessment of Disease Activity, Disease Activity Score (DAS) and Disease Activity Score with 28-Joint Counts (DAS28), Simplified Disease Activity Index (SDAI), C. Arthritis Care Res (Hoboken). November 2011;63 Suppl 1:S14-36.9. Toro-Gutiérrez CE, Arbeláez-Cortés Á, Fernández-Aldana AR, Mejía-Romero RA, Méndez Patarroyo P, Quintana L. G, et al. 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