Update on the epidemiology of carbapenemases in Latin America and the Caribbean

Introduction: Carbapenemases are β-lactamases able to hydrolyze a wide range of β-lactam antibiotics, including carbapenems. Carbapenemase production in Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp., with and without the co-expression of other β-lactamases is a serious public health threat. Carbapenemases belong to three main classes according to the Ambler classification: class A, class B, and class D. Areas covered: Carbapenemase-bearing pathogens are endemic in Latin America. In this review, we update the status of carbapenemases in Latin America and the Caribbean. Expert opinion: Understanding the current epidemiology of carbapenemases in Latin America and the Caribbean is of critical importance to improve infection control policies limiting the dissemination of multi-drug-resistant pathogens and in implementing appropriate antimicrobial therapy.

• Autores: Garcia Betancur, Juan Carlos; Appel, Tobias Manuel; Esparza, Germán Francisco; Gales, Ana; Levy-Hara, Gabriel; Cornistein, Wanda; Vega, Silvio; Nuñez, Duilio; Cuellar, Luis; Bavestrello, Luis; Castañeda-Méndez, Paulo F.; Villalobos-Vindas, Juan M.; Villegas, María Virginia
• Tipo de recurso: https://purl.org/coar/resource_type/c_6501
• Fecha de publicación: 2020
• Institución: Universidad El Bosque
• Repositorio: Repositorio U. El Bosque
• Idioma: eng
• OAI Identifier: oai:repositorio.unbosque.edu.co:20.500.12495/4222
• Acceso en línea: https://hdl.handle.net/20.500.12495/4222; https://doi.org/10.1080/14787210.2020.1813023
• Palabra clave: Acinetobacter baumannii; Carbapenem resistance; Carbapenem-resistant Enterobacterales (CRE); Carbapenemases; Carbapenems; Klebsiella pneumoniae; Pseudomonas aeruginosa
• License: Acceso abierto