1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds

The partition coefficients (P) of some synthesized cyanopyridine and chalcone compounds have been studied in 1-octanol-water system at different pH. It is observed that log P depends on pH and nature of substitution group present in the compounds. The central moiety also play important role to affec...

Full description

Autores:
Baluja, Shipra
Kulshrestha, Anchal
Movalia, Jagdish
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/66578
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/66578
http://bdigital.unal.edu.co/67606/
Palabra clave:
66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
coeficiente de reparto
cianopiridinas
chalconas
sistema 1-octanolagua
partition coefficient
cyanopyridines
chalcones
1-octanol-water system
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
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oai_identifier_str oai:repositorio.unal.edu.co:unal/66578
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
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spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Baluja, Shipra2dab78ea-4967-4a75-a62a-fc133c061777300Kulshrestha, Anchal59342249-1051-40d9-bab7-6ee71cb5ce1b300Movalia, Jagdishb75402aa-55b1-452d-bae9-47c820d8fae13002019-07-03T02:24:43Z2019-07-03T02:24:43Z2017-09-01ISSN: 1909-6356https://repositorio.unal.edu.co/handle/unal/66578http://bdigital.unal.edu.co/67606/The partition coefficients (P) of some synthesized cyanopyridine and chalcone compounds have been studied in 1-octanol-water system at different pH. It is observed that log P depends on pH and nature of substitution group present in the compounds. The central moiety also play important role to affect hydrophilic/hydrophobic nature of compounds. There is no regular trend for the variation of log P with different pH.Los coeficientes de reparto (P) de algunos compuestos sintetizados derivados de cianopiridina y chalcona se estudiaron en el sistema 1-octanol-agua a diferentes valores de pH. Se observa que log P depende del pH y de la naturaleza del gruposustituyente presente en los compuestos. El grupo central también desempeña un papel importante en la naturaleza hidrofílica/hidrofóbica de los compuestos. No hayuna tendencia regular para la variación de log P con el pH.application/pdfspaUniversidad Nacional de Colombia - Sede Bogotá - Facultad de Ciencias - Departamento de Farmaciahttps://revistas.unal.edu.co/index.php/rccquifa/article/view/69466Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico FarmacéuticasBaluja, Shipra and Kulshrestha, Anchal and Movalia, Jagdish (2017) 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds. Revista Colombiana de Ciencias Químico-Farmacéuticas, 46 (3). pp. 342-356. ISSN 1909-635666 Ingeniería química y Tecnologías relacionadas/ Chemical engineering61 Ciencias médicas; Medicina / Medicine and healthcoeficiente de repartocianopiridinaschalconassistema 1-octanolaguapartition coefficientcyanopyridineschalcones1-octanol-water system1-Octanol-water partition coefficient of some cyanopyridine and chalcone compoundsArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTORIGINAL69466-373550-1-PB.pdfapplication/pdf189987https://repositorio.unal.edu.co/bitstream/unal/66578/1/69466-373550-1-PB.pdfd3af771803d880af932838c5cb33ff1fMD51THUMBNAIL69466-373550-1-PB.pdf.jpg69466-373550-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg6099https://repositorio.unal.edu.co/bitstream/unal/66578/2/69466-373550-1-PB.pdf.jpg3c5d53504572a154361ed06c51a2fdccMD52unal/66578oai:repositorio.unal.edu.co:unal/665782023-05-25 23:03:15.201Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co
dc.title.spa.fl_str_mv 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
title 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
spellingShingle 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
coeficiente de reparto
cianopiridinas
chalconas
sistema 1-octanolagua
partition coefficient
cyanopyridines
chalcones
1-octanol-water system
title_short 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
title_full 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
title_fullStr 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
title_full_unstemmed 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
title_sort 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds
dc.creator.fl_str_mv Baluja, Shipra
Kulshrestha, Anchal
Movalia, Jagdish
dc.contributor.author.spa.fl_str_mv Baluja, Shipra
Kulshrestha, Anchal
Movalia, Jagdish
dc.subject.ddc.spa.fl_str_mv 66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
topic 66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
coeficiente de reparto
cianopiridinas
chalconas
sistema 1-octanolagua
partition coefficient
cyanopyridines
chalcones
1-octanol-water system
dc.subject.proposal.spa.fl_str_mv coeficiente de reparto
cianopiridinas
chalconas
sistema 1-octanolagua
partition coefficient
cyanopyridines
chalcones
1-octanol-water system
description The partition coefficients (P) of some synthesized cyanopyridine and chalcone compounds have been studied in 1-octanol-water system at different pH. It is observed that log P depends on pH and nature of substitution group present in the compounds. The central moiety also play important role to affect hydrophilic/hydrophobic nature of compounds. There is no regular trend for the variation of log P with different pH.
publishDate 2017
dc.date.issued.spa.fl_str_mv 2017-09-01
dc.date.accessioned.spa.fl_str_mv 2019-07-03T02:24:43Z
dc.date.available.spa.fl_str_mv 2019-07-03T02:24:43Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.type.content.spa.fl_str_mv Text
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format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.issn.spa.fl_str_mv ISSN: 1909-6356
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/66578
dc.identifier.eprints.spa.fl_str_mv http://bdigital.unal.edu.co/67606/
identifier_str_mv ISSN: 1909-6356
url https://repositorio.unal.edu.co/handle/unal/66578
http://bdigital.unal.edu.co/67606/
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.spa.fl_str_mv https://revistas.unal.edu.co/index.php/rccquifa/article/view/69466
dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico Farmacéuticas
Revista Colombiana de Ciencias Químico Farmacéuticas
dc.relation.references.spa.fl_str_mv Baluja, Shipra and Kulshrestha, Anchal and Movalia, Jagdish (2017) 1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds. Revista Colombiana de Ciencias Químico-Farmacéuticas, 46 (3). pp. 342-356. ISSN 1909-6356
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia - Sede Bogotá - Facultad de Ciencias - Departamento de Farmacia
institution Universidad Nacional de Colombia
bitstream.url.fl_str_mv https://repositorio.unal.edu.co/bitstream/unal/66578/1/69466-373550-1-PB.pdf
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