Adsorption of Erlotinib to Multiwalled Carbon Nanotubes

ABSTRACT: Objective: The objective of this research was to assess for the first time the adsorption of erlotinib (ERL) in three types of multi walled carbon nanotubes, as feasible alternative method to removal antineoplastic from wastewater. Methods: Both multi walled carbon nanotubes without modifi...

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Autores:
Pinillos Madrid, Juan Fernando
Rojas Vargas, Laura Daniela
Gallardo Cabrera, Cecilia
Tipo de recurso:
Article of investigation
Fecha de publicación:
2016
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/35697
Acceso en línea:
https://hdl.handle.net/10495/35697
https://journals.innovareacademics.in/index.php/ijpps/article/view/9580
Palabra clave:
Antineoplásicos
Antineoplastic Agents
Clorhidrato de Erlotinib
Erlotinib Hydrochloride
Nanotubos de Carbono
Nanotubes, Carbon
Aguas Residuales
Wastewater
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/
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network_acronym_str UDEA2
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repository_id_str
dc.title.spa.fl_str_mv Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
title Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
spellingShingle Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
Antineoplásicos
Antineoplastic Agents
Clorhidrato de Erlotinib
Erlotinib Hydrochloride
Nanotubos de Carbono
Nanotubes, Carbon
Aguas Residuales
Wastewater
title_short Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
title_full Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
title_fullStr Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
title_full_unstemmed Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
title_sort Adsorption of Erlotinib to Multiwalled Carbon Nanotubes
dc.creator.fl_str_mv Pinillos Madrid, Juan Fernando
Rojas Vargas, Laura Daniela
Gallardo Cabrera, Cecilia
dc.contributor.author.none.fl_str_mv Pinillos Madrid, Juan Fernando
Rojas Vargas, Laura Daniela
Gallardo Cabrera, Cecilia
dc.contributor.researchgroup.spa.fl_str_mv Grupo de Estabilidad de Medicamentos, Cosméticos y Alimentos (GEMCA)
dc.subject.decs.none.fl_str_mv Antineoplásicos
Antineoplastic Agents
Clorhidrato de Erlotinib
Erlotinib Hydrochloride
Nanotubos de Carbono
Nanotubes, Carbon
Aguas Residuales
topic Antineoplásicos
Antineoplastic Agents
Clorhidrato de Erlotinib
Erlotinib Hydrochloride
Nanotubos de Carbono
Nanotubes, Carbon
Aguas Residuales
Wastewater
dc.subject.agrovoc.none.fl_str_mv Wastewater
description ABSTRACT: Objective: The objective of this research was to assess for the first time the adsorption of erlotinib (ERL) in three types of multi walled carbon nanotubes, as feasible alternative method to removal antineoplastic from wastewater. Methods: Both multi walled carbon nanotubes without modification (pristine-CNT) and modified carbon nanotubes by oxidation (CNT-COOH) and amination (CNT-NH2 Results: The characterization showed that the surface of pristine-CNT was modified. Different sedimentation behavior was observed in the three types of CNTs. ERL adsorption followed the Langmuir model for CNT-NH) were used as adsorbents. They were characterized by Transmission electron microscopy, Raman spectroscopy, FT-IR spectroscopy, and Thermogravimetric analysis. In addition, the stability of CNTs suspensions were monitored. The ERL residual concentration in the equilibrium, from the bath adsorption, experiments was quantified by HPLC. The experiment data were fitted to Langmuir and Freundlich models. Conclusion: It was found that CNTs have a high capacity of adsorption of ERL, indicating the potential of CNTs to removal this antineoplastic drug from hospital wastewater.
publishDate 2016
dc.date.issued.none.fl_str_mv 2016
dc.date.accessioned.none.fl_str_mv 2023-06-28T19:35:23Z
dc.date.available.none.fl_str_mv 2023-06-28T19:35:23Z
dc.type.spa.fl_str_mv Artículo de investigación
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dc.identifier.citation.spa.fl_str_mv Pinillos JF, Rojas L, Gallardo C. ADSORPTION OF ERLOTINIB TO MULTIWALLED CARBON NANOTUBES. Int J Pharm Pharm Sci [Internet]. 2016 Jan. 1 [cited 2023 Jun. 29];8(1):399-403. Available from: https://journals.innovareacademics.in/index.php/ijpps/article/view/9580
dc.identifier.issn.none.fl_str_mv 0975-1491
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10495/35697
dc.identifier.eissn.none.fl_str_mv 2656-0097
dc.identifier.url.spa.fl_str_mv https://journals.innovareacademics.in/index.php/ijpps/article/view/9580
identifier_str_mv Pinillos JF, Rojas L, Gallardo C. ADSORPTION OF ERLOTINIB TO MULTIWALLED CARBON NANOTUBES. Int J Pharm Pharm Sci [Internet]. 2016 Jan. 1 [cited 2023 Jun. 29];8(1):399-403. Available from: https://journals.innovareacademics.in/index.php/ijpps/article/view/9580
0975-1491
2656-0097
url https://hdl.handle.net/10495/35697
https://journals.innovareacademics.in/index.php/ijpps/article/view/9580
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Int. J. Pharm. Pharm. Sci.
dc.relation.citationendpage.spa.fl_str_mv 403
dc.relation.citationissue.spa.fl_str_mv 1
dc.relation.citationstartpage.spa.fl_str_mv 399
dc.relation.citationvolume.spa.fl_str_mv 8
dc.relation.ispartofjournal.spa.fl_str_mv International Journal of Pharmacy and Pharmaceutical Sciences
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dc.publisher.place.spa.fl_str_mv Bhopal, India
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spelling Pinillos Madrid, Juan FernandoRojas Vargas, Laura DanielaGallardo Cabrera, CeciliaGrupo de Estabilidad de Medicamentos, Cosméticos y Alimentos (GEMCA)2023-06-28T19:35:23Z2023-06-28T19:35:23Z2016Pinillos JF, Rojas L, Gallardo C. ADSORPTION OF ERLOTINIB TO MULTIWALLED CARBON NANOTUBES. Int J Pharm Pharm Sci [Internet]. 2016 Jan. 1 [cited 2023 Jun. 29];8(1):399-403. Available from: https://journals.innovareacademics.in/index.php/ijpps/article/view/95800975-1491https://hdl.handle.net/10495/356972656-0097https://journals.innovareacademics.in/index.php/ijpps/article/view/9580ABSTRACT: Objective: The objective of this research was to assess for the first time the adsorption of erlotinib (ERL) in three types of multi walled carbon nanotubes, as feasible alternative method to removal antineoplastic from wastewater. Methods: Both multi walled carbon nanotubes without modification (pristine-CNT) and modified carbon nanotubes by oxidation (CNT-COOH) and amination (CNT-NH2 Results: The characterization showed that the surface of pristine-CNT was modified. Different sedimentation behavior was observed in the three types of CNTs. ERL adsorption followed the Langmuir model for CNT-NH) were used as adsorbents. They were characterized by Transmission electron microscopy, Raman spectroscopy, FT-IR spectroscopy, and Thermogravimetric analysis. In addition, the stability of CNTs suspensions were monitored. The ERL residual concentration in the equilibrium, from the bath adsorption, experiments was quantified by HPLC. The experiment data were fitted to Langmuir and Freundlich models. Conclusion: It was found that CNTs have a high capacity of adsorption of ERL, indicating the potential of CNTs to removal this antineoplastic drug from hospital wastewater.Departamento Administrativo de Ciencia, Tecnología e Innovación, COLCIENCIASCOL00351175application/pdfengIJPPSBhopal, Indiahttp://creativecommons.org/licenses/by/2.5/co/https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Adsorption of Erlotinib to Multiwalled Carbon NanotubesArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAntineoplásicosAntineoplastic AgentsClorhidrato de ErlotinibErlotinib HydrochlorideNanotubos de CarbonoNanotubes, CarbonAguas ResidualesWastewaterInt. J. Pharm. Pharm. 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