An Optimized Mouse Thigh Infection Model for Enterococci and its Impact on Antimicrobial Pharmacodynamics

Negligible in vivo growth of enterococci and high-level dispersion of data have led to inaccurate estimations of antibiotic pharmacodynamics (PD). Here we improved an in vivo model apt for PD studies by optimizing the in vitro culture conditions for enterococci. The PD of vancomycin (VAN), ampicilli...

Full description

Autores:

Agudelo Pérez, María
Rodríguez Jaramillo, Carlos Andrés
González Pérez, Javier Mauricio
Vesga Meneses, Omar
Zuluaga Salazar, Andrés Felipe

Tipo de recurso:

Article of investigation

Fecha de publicación:

2015

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/45705

Acceso en línea:

https://hdl.handle.net/10495/45705

Palabra clave:

Infecciones por Bacterias Grampositivas
Gram-Positive Bacterial Infections
Mice, Inbred ICR
Ratones Endogámicos ICR
Ampicillin
Ampicilina
Anaerobiosis
Anti-Bacterial Agents
Antibacterianos
Enterococcus faecalis
Microbial Sensitivity Tests
Pruebas de Sensibilidad Microbiana
Mucins
Mucinas
Piperacillin
Piperacilina
Sulbactam
Vancomycin
Vancomicina
3. Ciencias Médicas y de la Salud
https://id.nlm.nih.gov/mesh/D016908
https://id.nlm.nih.gov/mesh/D000667
https://id.nlm.nih.gov/mesh/D000693
https://id.nlm.nih.gov/mesh/D000900
https://id.nlm.nih.gov/mesh/D013293
https://id.nlm.nih.gov/mesh/D008813
https://id.nlm.nih.gov/mesh/D008826
https://id.nlm.nih.gov/mesh/D009077
https://id.nlm.nih.gov/mesh/D010878
https://id.nlm.nih.gov/mesh/D013407vvvvvvvvv
https://id.nlm.nih.gov/mesh/D014640
ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades

Rights

openAccess

License

http://creativecommons.org/licenses/by/4.0/