Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates

ABSTRACT: Background: Human milk is considered the best source of nutrition for young infants. However, if mothers cannot provide adequate breast milk or if infants are premature or have a low birth weight, breast-feeding must often be replaced or complemented with infant formulas (IFs). The interac...

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Autores:
Contreras Calderón, José del Carmen
Guerra Hernández, Eduardo Jesús
García Villanova, Belén
Tipo de recurso:
Article of investigation
Fecha de publicación:
2015
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/20707
Acceso en línea:
http://hdl.handle.net/10495/20707
Palabra clave:
Fórmulas infantiles
Infant Formula
Ácidos grasos
Fatty acids
Peroxidos
Peroxides
Lisina
Lysine
Proteinas lácteas
http://aims.fao.org/aos/agrovoc/c_2818
http://aims.fao.org/aos/agrovoc/c_5721
http://aims.fao.org/aos/agrovoc/c_4487
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/2.5/co/
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network_acronym_str UDEA2
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dc.title.spa.fl_str_mv Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
dc.title.translated.spa.fl_str_mv Modificación del valor nutricional durante el almacenamiento de fórmulas infantiles elaboradas con diferentes proteínas intactas, parcialemente hidrolizadas y carbohidratos
title Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
spellingShingle Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
Fórmulas infantiles
Infant Formula
Ácidos grasos
Fatty acids
Peroxidos
Peroxides
Lisina
Lysine
Proteinas lácteas
http://aims.fao.org/aos/agrovoc/c_2818
http://aims.fao.org/aos/agrovoc/c_5721
http://aims.fao.org/aos/agrovoc/c_4487
title_short Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
title_full Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
title_fullStr Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
title_full_unstemmed Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
title_sort Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates
dc.creator.fl_str_mv Contreras Calderón, José del Carmen
Guerra Hernández, Eduardo Jesús
García Villanova, Belén
dc.contributor.author.none.fl_str_mv Contreras Calderón, José del Carmen
Guerra Hernández, Eduardo Jesús
García Villanova, Belén
dc.contributor.researchgroup.spa.fl_str_mv BIOALI Biotecnología de Alimentos
dc.subject.decs.none.fl_str_mv Fórmulas infantiles
Infant Formula
topic Fórmulas infantiles
Infant Formula
Ácidos grasos
Fatty acids
Peroxidos
Peroxides
Lisina
Lysine
Proteinas lácteas
http://aims.fao.org/aos/agrovoc/c_2818
http://aims.fao.org/aos/agrovoc/c_5721
http://aims.fao.org/aos/agrovoc/c_4487
dc.subject.agrovoc.none.fl_str_mv Ácidos grasos
Fatty acids
Peroxidos
Peroxides
Lisina
Lysine
dc.subject.proposal.spa.fl_str_mv Proteinas lácteas
dc.subject.agrovocuri.none.fl_str_mv http://aims.fao.org/aos/agrovoc/c_2818
http://aims.fao.org/aos/agrovoc/c_5721
http://aims.fao.org/aos/agrovoc/c_4487
description ABSTRACT: Background: Human milk is considered the best source of nutrition for young infants. However, if mothers cannot provide adequate breast milk or if infants are premature or have a low birth weight, breast-feeding must often be replaced or complemented with infant formulas (IFs). The interactions between infant formula components (proteins, fats, carbohydrates, vitamin and minerals) mainly affect carbohydrates and proteins (Maillard reaction, MR), but those involving proteins are especially important in products used in infant feeding because of the high protein requirements of infants. On the other hand, fatty acids (FAs) are considered important in infant development. Objectives: The aim of the present work was to test the stability of IFs made with different ingredients, analyzing the available lysine losses (for protein stability) and the FAs content and the peroxide value (for fat stability) during stored at normal and adverse conditions and to propose a faster control of that stability. Methods: Available lysine analyzed by high-performance liquid chromatography (HPLC), lipid oxidation by titrimetric method and FAs profile by gas chromatography (GC) were determined in four types of IFs prepared with intact and partially hydrolyzed proteins and different carbohydrates (lactose or maltodextrins) during storage at 4, 20 and 30 ºC for 24 months at normal water activity (Aw=0.1-0.4), and at Aw of 0.65 at 20 and 30 ºC for 4 weeks. These IFs were prepared twice (IF1 and IF2) in different batches by a Spanish dietary product company. Results: At 30ºC, available lysine losses were 40-50% in all IFs analyzed. The behavior and percentage lysine loss between 1 and 4 weeks of storage at 30 °C with Aw=0.65 was similar to those obtained after 24 months of storage at 30 °C. No significant changes were observed in fatty acid profile during storage. Oxidation was only observed in opened packs and after 4 weeks/30 °C/Aw=0.65. Conclusions: The losses of available lysine increase to higher time and storage temperatures. The FAs shows a good stability for any storage condition; however peroxide values prove more sensitive than FAs changes for evaluating fat oxidation during the storage of IFs.
publishDate 2015
dc.date.issued.none.fl_str_mv 2015
dc.date.accessioned.none.fl_str_mv 2021-07-08T17:30:29Z
dc.date.available.none.fl_str_mv 2021-07-08T17:30:29Z
dc.type.spa.fl_str_mv Artículo de investigación
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dc.type.redcol.spa.fl_str_mv https://purl.org/redcol/resource_type/ART
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dc.identifier.issn.none.fl_str_mv 0121-4004
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/20707
dc.identifier.doi.none.fl_str_mv 10.17533/udea.vitae.v22n2a03
dc.identifier.eissn.none.fl_str_mv 2145-2660
identifier_str_mv 0121-4004
10.17533/udea.vitae.v22n2a03
2145-2660
url http://hdl.handle.net/10495/20707
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Vitae
dc.relation.citationendpage.spa.fl_str_mv 100
dc.relation.citationissue.spa.fl_str_mv 2
dc.relation.citationstartpage.spa.fl_str_mv 87
dc.relation.citationvolume.spa.fl_str_mv 22
dc.relation.ispartofjournal.spa.fl_str_mv Vitae
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dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad de Antioquia, Facultad de Ciencias Farmacéuticas y Alimentarias
dc.publisher.place.spa.fl_str_mv Medellín, Colombia
institution Universidad de Antioquia
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spelling Contreras Calderón, José del CarmenGuerra Hernández, Eduardo JesúsGarcía Villanova, BelénBIOALI Biotecnología de Alimentos2021-07-08T17:30:29Z2021-07-08T17:30:29Z20150121-4004http://hdl.handle.net/10495/2070710.17533/udea.vitae.v22n2a032145-2660ABSTRACT: Background: Human milk is considered the best source of nutrition for young infants. However, if mothers cannot provide adequate breast milk or if infants are premature or have a low birth weight, breast-feeding must often be replaced or complemented with infant formulas (IFs). The interactions between infant formula components (proteins, fats, carbohydrates, vitamin and minerals) mainly affect carbohydrates and proteins (Maillard reaction, MR), but those involving proteins are especially important in products used in infant feeding because of the high protein requirements of infants. On the other hand, fatty acids (FAs) are considered important in infant development. Objectives: The aim of the present work was to test the stability of IFs made with different ingredients, analyzing the available lysine losses (for protein stability) and the FAs content and the peroxide value (for fat stability) during stored at normal and adverse conditions and to propose a faster control of that stability. Methods: Available lysine analyzed by high-performance liquid chromatography (HPLC), lipid oxidation by titrimetric method and FAs profile by gas chromatography (GC) were determined in four types of IFs prepared with intact and partially hydrolyzed proteins and different carbohydrates (lactose or maltodextrins) during storage at 4, 20 and 30 ºC for 24 months at normal water activity (Aw=0.1-0.4), and at Aw of 0.65 at 20 and 30 ºC for 4 weeks. These IFs were prepared twice (IF1 and IF2) in different batches by a Spanish dietary product company. Results: At 30ºC, available lysine losses were 40-50% in all IFs analyzed. The behavior and percentage lysine loss between 1 and 4 weeks of storage at 30 °C with Aw=0.65 was similar to those obtained after 24 months of storage at 30 °C. No significant changes were observed in fatty acid profile during storage. Oxidation was only observed in opened packs and after 4 weeks/30 °C/Aw=0.65. Conclusions: The losses of available lysine increase to higher time and storage temperatures. The FAs shows a good stability for any storage condition; however peroxide values prove more sensitive than FAs changes for evaluating fat oxidation during the storage of IFs.RESUMEN: Antecedentes: La leche materna es la mejor fuente nutricional para niños recién nacidos. Sin embargo, cuando las madres no pueden proveer leche, o si los niños son prematuros o tienen bajo peso al nacer, la lactancia debe ser reemplazada o complementada con fórmulas infantiles (IFs). La interacción entre los componentes de las IFs (proteínas, grasas, carbohidratos, vitaminas y minerales) principalmente afecta carbohidratos y proteínas (Reacción de Maillard, MR), pero los que implican proteínas son especialmente importantes en alimentación infantil debido a los altos requerimientos de proteína de los lactantes. Por otra parte, los ácidos grasos (FAs) son considerados importantes en el desarrollo de los niños. Objetivos: El objetivo fue evaluar la estabilidad de IFs elaboradas con diferentes ingredientes, analizando lisina útil (para estabilidad de proteínas), contenido de FAs y valor de peróxidos (para estabilidad de grasas) durante el almacenamiento bajo condiciones normales y adversas, y proponer un control más rápido de la estabilidad. Metodos: Los análisis de lisina útil por cromatografía liquida de alta resolución (HPLC), oxidación lipídica por el método de titulación y el perfil de FAs por cromatografía de gases (GC) fueron determinados en cuatro tipos de IFs preparadas con proteínas intactas y parcialmente hidrolizadas con diferentes carbo hidratos (lactosa y maltodextrinas) durante el almacenamiento a 4, 20 y 30 ºC por 24 meses a actividad de agua normal (Aw=0,1-0,4), y a Aw de 0,65 a 20 y 30 ºC por 4 semanas. Estas IFs fueron preparadas dos veces (IF1 y IF2) en baches diferentes por una empresa Española de productos dietarios. Resultados: A 30ºC, las pérdidas de lisina útil fueron de 40-50% en todas las IFs analizadas. El comportamiento y porcentaje de pérdidas de lisina entre la 1 y 4 semana de conservación a 30 °C con Aw=0,65 fue similar a las obtenidas tras 24 de almacenamiento a 30 °C. No se observaron cambios significativos en el perfil de FAs durante el almacenamiento. Oxidación solo se observo en los envases abiertos y después de 4 semanas/30 °C/Aw=0.65. Conclusiones: Las pérdidas de lisina útil incrementan a mayor tiempo y tem peratura de almacenamiento. Los FAs muestran una buena estabilidad para cualquiera de las condiciones de almacenamiento, sin embargo el valor de peróxidos evidencia mayor sensibilidad que los cambios en FAs para evaluar la oxidación de las grasas durante el almacenamiento de IFs.COL003837914application/pdfengUniversidad de Antioquia, Facultad de Ciencias Farmacéuticas y AlimentariasMedellín, Colombiahttp://creativecommons.org/licenses/by-nc-sa/2.5/co/https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydratesModificación del valor nutricional durante el almacenamiento de fórmulas infantiles elaboradas con diferentes proteínas intactas, parcialemente hidrolizadas y carbohidratosArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionFórmulas infantilesInfant FormulaÁcidos grasosFatty acidsPeroxidosPeroxidesLisinaLysineProteinas lácteashttp://aims.fao.org/aos/agrovoc/c_2818http://aims.fao.org/aos/agrovoc/c_5721http://aims.fao.org/aos/agrovoc/c_4487Vitae10028722VitaePublicationORIGINALContrerasJose_2015_ModificationNutritionalHydrolyzed.pdfContrerasJose_2015_ModificationNutritionalHydrolyzed.pdfArtículo de investigaciónapplication/pdf219494https://bibliotecadigital.udea.edu.co/bitstreams/5c11323d-9008-4db9-b85a-c5de0faad38b/downloade6ae9e5013fb2650381211f25ab35f86MD51trueAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; 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