Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention
ABSTRACT: Colorectal cancer (CRC) is the third most common cancer worldwide and its incidence is expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly due to low consumption of phytochemicals present in fruits and vegetables. Hence, this paper reviews the most pr...
- Autores:
-
Alzate Yepes, Teresita
Pérez Palacio, Lorena
Martínez Correa, Estefanía
Osorio Delgado, Marlon Andrés
- Tipo de recurso:
- Review article
- Fecha de publicación:
- 2023
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/43536
- Acceso en línea:
- https://hdl.handle.net/10495/43536
- Palabra clave:
- Fitoquímicos
Phytochemicals
Quimioprevención
Chemoprevention
Dieta
Diet
Neoplasias Colorrectales
Colorectal Neoplasms
Frutas - química
Fruit - chemistry
Verduras - química
Vegetables - chemistry
https://id.nlm.nih.gov/mesh/D005638
https://id.nlm.nih.gov/mesh/D064209
https://id.nlm.nih.gov/mesh/D018890
https://id.nlm.nih.gov/mesh/D004032
https://id.nlm.nih.gov/mesh/D015179
https://id.nlm.nih.gov/mesh/D014675
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
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Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention |
| title |
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention |
| spellingShingle |
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention Fitoquímicos Phytochemicals Quimioprevención Chemoprevention Dieta Diet Neoplasias Colorrectales Colorectal Neoplasms Frutas - química Fruit - chemistry Verduras - química Vegetables - chemistry https://id.nlm.nih.gov/mesh/D005638 https://id.nlm.nih.gov/mesh/D064209 https://id.nlm.nih.gov/mesh/D018890 https://id.nlm.nih.gov/mesh/D004032 https://id.nlm.nih.gov/mesh/D015179 https://id.nlm.nih.gov/mesh/D014675 |
| title_short |
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention |
| title_full |
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention |
| title_fullStr |
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention |
| title_full_unstemmed |
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention |
| title_sort |
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention |
| dc.creator.fl_str_mv |
Alzate Yepes, Teresita Pérez Palacio, Lorena Martínez Correa, Estefanía Osorio Delgado, Marlon Andrés |
| dc.contributor.author.none.fl_str_mv |
Alzate Yepes, Teresita Pérez Palacio, Lorena Martínez Correa, Estefanía Osorio Delgado, Marlon Andrés |
| dc.contributor.researchgroup.spa.fl_str_mv |
GIIESEN Grupo de Investigación Interdisciplinaria en Educación para la Salud y Educación Nutricional |
| dc.subject.decs.none.fl_str_mv |
Fitoquímicos Phytochemicals Quimioprevención Chemoprevention Dieta Diet Neoplasias Colorrectales Colorectal Neoplasms Frutas - química Fruit - chemistry Verduras - química Vegetables - chemistry |
| topic |
Fitoquímicos Phytochemicals Quimioprevención Chemoprevention Dieta Diet Neoplasias Colorrectales Colorectal Neoplasms Frutas - química Fruit - chemistry Verduras - química Vegetables - chemistry https://id.nlm.nih.gov/mesh/D005638 https://id.nlm.nih.gov/mesh/D064209 https://id.nlm.nih.gov/mesh/D018890 https://id.nlm.nih.gov/mesh/D004032 https://id.nlm.nih.gov/mesh/D015179 https://id.nlm.nih.gov/mesh/D014675 |
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https://id.nlm.nih.gov/mesh/D005638 |
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https://id.nlm.nih.gov/mesh/D064209 https://id.nlm.nih.gov/mesh/D018890 https://id.nlm.nih.gov/mesh/D004032 https://id.nlm.nih.gov/mesh/D015179 https://id.nlm.nih.gov/mesh/D014675 |
| description |
ABSTRACT: Colorectal cancer (CRC) is the third most common cancer worldwide and its incidence is expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly due to low consumption of phytochemicals present in fruits and vegetables. Hence, this paper reviews the most promising phytochemicals in the literature, presenting scientific evidence regarding potential CRC chemopreventive effects. Moreover, this paper reveals the structure and action of CRC mechanisms that these phytochemicals are involved in. The review reveals that vegetables rich in phytochemicals such as carrots and green leafy vegetables, as well as some fruits such as pineapple, citrus fruits, papaya, mango, and Cape gooseberry, that have antioxidant, anti-inflammatory, and chemopreventive properties can promote a healthy colonic environment. Fruits and vegetables in the daily diet promote antitumor mechanisms by regulating cell signaling and/or proliferation pathways. Hence, daily consumption of these plant products is recommended to reduce the risk of CRC. |
| publishDate |
2023 |
| dc.date.issued.none.fl_str_mv |
2023 |
| dc.date.accessioned.none.fl_str_mv |
2024-11-17T15:52:36Z |
| dc.date.available.none.fl_str_mv |
2024-11-17T15:52:36Z |
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Artículo de revisión |
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Alzate-Yepes T, Pérez-Palacio L, Martínez E, Osorio M. Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention. Molecules. 2023 May 24;28(11):4322. doi: 10.3390/molecules28114322. |
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https://hdl.handle.net/10495/43536 |
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10.3390/molecules28114322 |
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1420-3049 |
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Alzate-Yepes T, Pérez-Palacio L, Martínez E, Osorio M. Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention. Molecules. 2023 May 24;28(11):4322. doi: 10.3390/molecules28114322. 10.3390/molecules28114322 1420-3049 |
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https://hdl.handle.net/10495/43536 |
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eng |
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eng |
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Molecules |
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17 |
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28 |
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Molecules |
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Alzate Yepes, TeresitaPérez Palacio, LorenaMartínez Correa, EstefaníaOsorio Delgado, Marlon AndrésGIIESEN Grupo de Investigación Interdisciplinaria en Educación para la Salud y Educación Nutricional2024-11-17T15:52:36Z2024-11-17T15:52:36Z2023Alzate-Yepes T, Pérez-Palacio L, Martínez E, Osorio M. Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention. Molecules. 2023 May 24;28(11):4322. doi: 10.3390/molecules28114322.https://hdl.handle.net/10495/4353610.3390/molecules281143221420-3049ABSTRACT: Colorectal cancer (CRC) is the third most common cancer worldwide and its incidence is expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly due to low consumption of phytochemicals present in fruits and vegetables. Hence, this paper reviews the most promising phytochemicals in the literature, presenting scientific evidence regarding potential CRC chemopreventive effects. Moreover, this paper reveals the structure and action of CRC mechanisms that these phytochemicals are involved in. The review reveals that vegetables rich in phytochemicals such as carrots and green leafy vegetables, as well as some fruits such as pineapple, citrus fruits, papaya, mango, and Cape gooseberry, that have antioxidant, anti-inflammatory, and chemopreventive properties can promote a healthy colonic environment. Fruits and vegetables in the daily diet promote antitumor mechanisms by regulating cell signaling and/or proliferation pathways. Hence, daily consumption of these plant products is recommended to reduce the risk of CRC.Colombia. Ministerio de Ciencia, Tecnología e Innovación - MinCienciasColombia. Ministerio de Educación Nacional - MinEducaciónColombia. 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