Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species
ABSTRACT: The antiprotozoal activity of 26 ethanol extracts derived from 13 species of the genus Bomarea (Alstroemeriaceae) were evaluated against the promastigote forms of three Leishmania species (L. amazonensis L.,L. braziliensis Vianna, and L. donovani Laveran & Mesnil) and the epimastigote...
- Autores:
-
Alzate Guarín, Fernando
Jiménez Úsuga, Nora Del Socorro
Weniger, Bernard
Bastida Armengol, Jaume
Gimenez, Alberto
Ruiz, Grace
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2008
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/36494
- Acceso en línea:
- https://hdl.handle.net/10495/36494
- Palabra clave:
- Liliales
Biodiversidad
Biodiversity
Fitoalexinas
Phytoalexins
Enfermedades Transmisibles
Communicable Diseases
Terapéutica
Therapeutics
Colombia
Bomarea
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/
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| dc.title.spa.fl_str_mv |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| title |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| spellingShingle |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species Liliales Biodiversidad Biodiversity Fitoalexinas Phytoalexins Enfermedades Transmisibles Communicable Diseases Terapéutica Therapeutics Colombia Bomarea |
| title_short |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| title_full |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| title_fullStr |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| title_full_unstemmed |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| title_sort |
Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| dc.creator.fl_str_mv |
Alzate Guarín, Fernando Jiménez Úsuga, Nora Del Socorro Weniger, Bernard Bastida Armengol, Jaume Gimenez, Alberto Ruiz, Grace |
| dc.contributor.author.none.fl_str_mv |
Alzate Guarín, Fernando Jiménez Úsuga, Nora Del Socorro Weniger, Bernard Bastida Armengol, Jaume Gimenez, Alberto Ruiz, Grace |
| dc.contributor.researchgroup.spa.fl_str_mv |
Grupo de Investigación en Sustancias Bioactivas (GISB) |
| dc.subject.decs.none.fl_str_mv |
Liliales Biodiversidad Biodiversity Fitoalexinas Phytoalexins Enfermedades Transmisibles Communicable Diseases Terapéutica Therapeutics Colombia |
| topic |
Liliales Biodiversidad Biodiversity Fitoalexinas Phytoalexins Enfermedades Transmisibles Communicable Diseases Terapéutica Therapeutics Colombia Bomarea |
| dc.subject.proposal.spa.fl_str_mv |
Bomarea |
| description |
ABSTRACT: The antiprotozoal activity of 26 ethanol extracts derived from 13 species of the genus Bomarea (Alstroemeriaceae) were evaluated against the promastigote forms of three Leishmania species (L. amazonensis L.,L. braziliensis Vianna, and L. donovani Laveran & Mesnil) and the epimastigote form of Trypanosoma cruzi Chagas. IC50 values for leishmanicidal activities were between 4.9 and 98.6 μg/mL, B. setacea extracts being the most active against the three species of Leishmania. Amphotericin B (IC50 = 0.2 μg/mL) and pentamidine (IC50 = 10 μg/mL) were used as control in this assay. IC50 values for antitrypanosomal activities were between 65.2 and 92.7 μg/mL, whereas the control benznidazole had an IC50 value of 2 μg/mL. |
| publishDate |
2008 |
| dc.date.issued.none.fl_str_mv |
2008 |
| dc.date.accessioned.none.fl_str_mv |
2023-09-01T13:49:52Z |
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2023-09-01T13:49:52Z |
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Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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https://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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Fernando Alzate, Nora Jimenez, Bernard Weniger, Jaume Bastida & Alberto Gimenez (2008) Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species, Pharmaceutical Biology, 46:9, 575-578, DOI: 10.1080/13880200801968904 |
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1388-0209 |
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https://hdl.handle.net/10495/36494 |
| dc.identifier.doi.none.fl_str_mv |
10.1080/13880200801968904 |
| dc.identifier.eissn.none.fl_str_mv |
1744-5116 |
| identifier_str_mv |
Fernando Alzate, Nora Jimenez, Bernard Weniger, Jaume Bastida & Alberto Gimenez (2008) Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species, Pharmaceutical Biology, 46:9, 575-578, DOI: 10.1080/13880200801968904 1388-0209 10.1080/13880200801968904 1744-5116 |
| url |
https://hdl.handle.net/10495/36494 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Pharm. Biol. |
| dc.relation.citationendpage.spa.fl_str_mv |
578 |
| dc.relation.citationissue.spa.fl_str_mv |
9 |
| dc.relation.citationstartpage.spa.fl_str_mv |
575 |
| dc.relation.citationvolume.spa.fl_str_mv |
46 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Pharmaceutical Biology |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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application/pdf |
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Taylor and Francis Open Access |
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Lisse, Países Bajos |
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Universidad de Antioquia |
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Alzate Guarín, FernandoJiménez Úsuga, Nora Del SocorroWeniger, BernardBastida Armengol, JaumeGimenez, AlbertoRuiz, GraceGrupo de Investigación en Sustancias Bioactivas (GISB)2023-09-01T13:49:52Z2023-09-01T13:49:52Z2008Fernando Alzate, Nora Jimenez, Bernard Weniger, Jaume Bastida & Alberto Gimenez (2008) Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species, Pharmaceutical Biology, 46:9, 575-578, DOI: 10.1080/138802008019689041388-0209https://hdl.handle.net/10495/3649410.1080/138802008019689041744-5116ABSTRACT: The antiprotozoal activity of 26 ethanol extracts derived from 13 species of the genus Bomarea (Alstroemeriaceae) were evaluated against the promastigote forms of three Leishmania species (L. amazonensis L.,L. braziliensis Vianna, and L. donovani Laveran & Mesnil) and the epimastigote form of Trypanosoma cruzi Chagas. IC50 values for leishmanicidal activities were between 4.9 and 98.6 μg/mL, B. setacea extracts being the most active against the three species of Leishmania. Amphotericin B (IC50 = 0.2 μg/mL) and pentamidine (IC50 = 10 μg/mL) were used as control in this assay. IC50 values for antitrypanosomal activities were between 65.2 and 92.7 μg/mL, whereas the control benznidazole had an IC50 value of 2 μg/mL.COL00103595application/pdfengTaylor and Francis Open AccessLisse, Países Bajoshttps://creativecommons.org/licenses/by-nc-nd/4.0/http://creativecommons.org/licenses/by-nc-nd/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Antiprotozoal Activity of Ethanol Extracts of Some Bomarea SpeciesArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionLilialesBiodiversidadBiodiversityFitoalexinasPhytoalexinsEnfermedades TransmisiblesCommunicable DiseasesTerapéuticaTherapeuticsColombiaBomareaPharm. 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