Anti-inflammatory and hypolipidemic mechanisms of Eucalyptus tereticornis leaf extract
ABSTRACT: Obesity is a complex condition with adipocyte hypertrophy as an important source for the development of adipose tissue inflammation that plays a central role in the pathogenesis of many obesity-associated complications. Ursolic acid (UA), Oleanolic acid (OA) and Ursolic acid lactone (UAL)...
- Autores:
-
Acín Martínez, Sergio
Betancur Ocampo, Laura Isabel
Echeverri López, Luis Fernando
Muñoz, Diana Lorena
Balcázar Morales, Norman
- Tipo de recurso:
- http://purl.org/coar/resource_type/c_6670
- Fecha de publicación:
- 2022
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/34756
- Acceso en línea:
- https://hdl.handle.net/10495/34756
- Palabra clave:
- Antiinflamatorios
Anti-Inflammatory Agents
Obesidad
Obesity
Hipolipemiantes
Hypolipidemic Agents
Eucalyptus tereticornis
Extractos Vegetales
Plant Extracts
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-sa/2.5/co/
| Summary: | ABSTRACT: Obesity is a complex condition with adipocyte hypertrophy as an important source for the development of adipose tissue inflammation that plays a central role in the pathogenesis of many obesity-associated complications. Ursolic acid (UA), Oleanolic acid (OA) and Ursolic acid lactone (UAL) are the main molecules (78%) in a Eucalyptus tereticornis (Eu) extract (OBE100). This enriched-triterpene fraction mixed with unknown minor metabolites has a synergistic effect providing superior anti-inflammatory and hypolipidemic effects than reconstituted triterpenoid. |
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