Sodium-calcium exchanger-3 regulates pain ‘‘wind- up’’: From human psychophysics to spinal mech- anisms

ABSTRACT: Repeated application of noxious stimuli leads to a progressively increased pain perception; this temporal sum-mation is enhanced in and predictive of clinical pain disorders. Its electrophysiological correlate is ‘‘wind-up,’’ in which dorsal horn spinal neurons increase their response to r...

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Autores:

Ramírez Aristeguieta, Luis Miguel
Bedoya Berrío, Gabriel de Jesús
Ruíz Linares, Andrés
Patel, Ryan
Polgár, Erika
Chisholm, Kim I.
Middleton, Steven J.
Boyle, Kieran
Dickie, Allen C.
Semizoglou, Evangelia
Pérez Sánchez, Jimena
Bell, Andrew M.
Trendafilova, Teodora
Khoury, Samar
Ivanov, Aleksandar
Wildner, Hendrik
Ferris, Eleanor
Chacón Duque, Juan Camilo
Sokolow, Sophie
Saad Boghdady, Mohamed A.
Herchuelz, André
Faux, Pierre
Poletti, Giovanni
Rothhammer, Francisco
Gallo, Carla
Adhikari, Kaustubh
Ulrich Zeilhofer, Hanns
Diatchenko, Luda
McMahon, Stephen B.
Todd, Andrew J.
Dickenson, Anthony H.
Schmid, Annina B.
Bennett, David L.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/35175

Acceso en línea:

https://hdl.handle.net/10495/35175

Palabra clave:

Umbral del Dolor
Pain Threshold
Manejo del Dolor
Pain Management
Proteínas Sensoras del Calcio Intracelular
Intracellular Calcium-Sensing Proteins
Intercambiador de Sodio-Calcio
Sodium-Calcium Exchanger
Nervios Espinales
Spinal Nerves

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/