Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome
ABSTRACT: Metabolic syndrome (MetS) is characterized by increased oxidative stress and a pro-inflammatory state. Vaccinium meridionale Swartz (known as “agraz”) is a berry rich in polyphenolic compounds with demonstrated antioxidant activity and anti-inflammatory effects in preclinical studies. The...
- Autores:
-
Espinosa Moncada, Juliana
Marín Echeverri, Catalina
Galvis Pérez, Yeisson
Ciro Gómez, Gelmy Luz
Aristizábal Rivera, Juan Carlos
Blesso, Christopher N.
Fernández, María Luz
Barona Acevedo, María Jacqueline
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/11618
- Acceso en línea:
- http://hdl.handle.net/10495/11618
- Palabra clave:
- Vaccinium meridionale
Metabolic syndrome
Polyphenols
Berries
Andean berry
Intervention
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-sa/2.5/co/
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Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome |
| title |
Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome |
| spellingShingle |
Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome Vaccinium meridionale Metabolic syndrome Polyphenols Berries Andean berry Intervention |
| title_short |
Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome |
| title_full |
Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome |
| title_fullStr |
Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome |
| title_full_unstemmed |
Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome |
| title_sort |
Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome |
| dc.creator.fl_str_mv |
Espinosa Moncada, Juliana Marín Echeverri, Catalina Galvis Pérez, Yeisson Ciro Gómez, Gelmy Luz Aristizábal Rivera, Juan Carlos Blesso, Christopher N. Fernández, María Luz Barona Acevedo, María Jacqueline |
| dc.contributor.author.none.fl_str_mv |
Espinosa Moncada, Juliana Marín Echeverri, Catalina Galvis Pérez, Yeisson Ciro Gómez, Gelmy Luz Aristizábal Rivera, Juan Carlos Blesso, Christopher N. Fernández, María Luz Barona Acevedo, María Jacqueline |
| dc.contributor.researchgroup.spa.fl_str_mv |
Grupo de Investigación en Fisiología y Bioquímica - Physis Toxinología, Alternativas Terapéuticas y Alimentarias |
| dc.subject.none.fl_str_mv |
Vaccinium meridionale Metabolic syndrome Polyphenols Berries Andean berry Intervention |
| topic |
Vaccinium meridionale Metabolic syndrome Polyphenols Berries Andean berry Intervention |
| description |
ABSTRACT: Metabolic syndrome (MetS) is characterized by increased oxidative stress and a pro-inflammatory state. Vaccinium meridionale Swartz (known as “agraz”) is a berry rich in polyphenolic compounds with demonstrated antioxidant activity and anti-inflammatory effects in preclinical studies. The aim of this study was to evaluate the effects of agraz consumption on inflammatory and oxidative stress markers in women with MetS. Forty women with MetS (47 ± 9 years) were randomly assigned to consume daily either 200 mL of agraz nectar or placebo over four weeks in a double-blind, cross-over design study, separated by a 4-week washout period. Metabolic and inflammatory markers in serum and antioxidant/oxidative stress markers in serum and urine were assessed at the end of each period. Serum antioxidant capacity measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method was significantly higher (p = 0.028), while urinary 8-hydroxy-2-deoxyguanosine (8-OHdG) was lower (p = 0.041) after agraz consumption, compared to placebo. In conclusion, consumption of agraz during four weeks increased serum antioxidant capacity and decreased a marker of DNA oxidative damage in women with MetS, compared to placebo. These results suggest that agraz consumption may play a protective role in patients with MetS. |
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2018 |
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2018 |
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2019-08-06T19:10:50Z |
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2019-08-06T19:10:50Z |
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Artículo de investigación |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Espinosa-Moncada J, Marín-Echeverri C, Galvis-Pérez Y, Ciro-Gómez G, Aristizábal J, et al. Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome. Nutrients, 2018; 10(11): 1639. DOI: 10.3390/nu10111639 |
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2072-6643 |
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http://hdl.handle.net/10495/11618 |
| dc.identifier.doi.none.fl_str_mv |
10.3390/nu10111639 |
| identifier_str_mv |
Espinosa-Moncada J, Marín-Echeverri C, Galvis-Pérez Y, Ciro-Gómez G, Aristizábal J, et al. Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome. Nutrients, 2018; 10(11): 1639. DOI: 10.3390/nu10111639 2072-6643 10.3390/nu10111639 |
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http://hdl.handle.net/10495/11618 |
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eng |
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eng |
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Nutrients |
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15 |
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11 |
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1 |
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10 |
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Nutrients |
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Basilea, Suiza |
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Espinosa Moncada, JulianaMarín Echeverri, CatalinaGalvis Pérez, YeissonCiro Gómez, Gelmy LuzAristizábal Rivera, Juan CarlosBlesso, Christopher N.Fernández, María LuzBarona Acevedo, María JacquelineGrupo de Investigación en Fisiología y Bioquímica - PhysisToxinología, Alternativas Terapéuticas y Alimentarias2019-08-06T19:10:50Z2019-08-06T19:10:50Z2018Espinosa-Moncada J, Marín-Echeverri C, Galvis-Pérez Y, Ciro-Gómez G, Aristizábal J, et al. Evaluation of agraz consumption on adipocytokines, inflammation, and oxidative stress markers in women with metabolic syndrome. Nutrients, 2018; 10(11): 1639. DOI: 10.3390/nu101116392072-6643http://hdl.handle.net/10495/1161810.3390/nu10111639ABSTRACT: Metabolic syndrome (MetS) is characterized by increased oxidative stress and a pro-inflammatory state. Vaccinium meridionale Swartz (known as “agraz”) is a berry rich in polyphenolic compounds with demonstrated antioxidant activity and anti-inflammatory effects in preclinical studies. The aim of this study was to evaluate the effects of agraz consumption on inflammatory and oxidative stress markers in women with MetS. Forty women with MetS (47 ± 9 years) were randomly assigned to consume daily either 200 mL of agraz nectar or placebo over four weeks in a double-blind, cross-over design study, separated by a 4-week washout period. Metabolic and inflammatory markers in serum and antioxidant/oxidative stress markers in serum and urine were assessed at the end of each period. Serum antioxidant capacity measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method was significantly higher (p = 0.028), while urinary 8-hydroxy-2-deoxyguanosine (8-OHdG) was lower (p = 0.041) after agraz consumption, compared to placebo. In conclusion, consumption of agraz during four weeks increased serum antioxidant capacity and decreased a marker of DNA oxidative damage in women with MetS, compared to placebo. 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