Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives
ABSTRACT: Marine organisms represent a new extensive source for bioactive molecules. They have the potential to provide new therapeutic alternatives to treat human diseases. In this paper, we describe and discuss a variety of isolated and semisynthetic molecules obtained from marine phase II, phase...
- Autores:
-
Galeano Jaramillo, Elkin de Jesús
Martínez Martínez, Alejandro
Rojas, Jhon J.
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2011
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/36367
- Acceso en línea:
- https://hdl.handle.net/10495/36367
- Palabra clave:
- Animales
Animals
Productos Biológicos - aislamiento y purificación
Biological Products - isolation y purification
Productos Biológicos - farmacología
Productos Biológicos - pharmacology
Descubrimiento de Drogas
Drug Discovery
Océanos y Mares
Oceans and Seas
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc/2.5/co/
| id |
UDEA2_d94b0b705079d581548c53bf660b6da6 |
|---|---|
| oai_identifier_str |
oai:bibliotecadigital.udea.edu.co:10495/36367 |
| network_acronym_str |
UDEA2 |
| network_name_str |
Repositorio UdeA |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives |
| title |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives |
| spellingShingle |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives Animales Animals Productos Biológicos - aislamiento y purificación Biological Products - isolation y purification Productos Biológicos - farmacología Productos Biológicos - pharmacology Descubrimiento de Drogas Drug Discovery Océanos y Mares Oceans and Seas |
| title_short |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives |
| title_full |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives |
| title_fullStr |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives |
| title_full_unstemmed |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives |
| title_sort |
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives |
| dc.creator.fl_str_mv |
Galeano Jaramillo, Elkin de Jesús Martínez Martínez, Alejandro Rojas, Jhon J. |
| dc.contributor.author.none.fl_str_mv |
Galeano Jaramillo, Elkin de Jesús Martínez Martínez, Alejandro Rojas, Jhon J. |
| dc.contributor.researchgroup.spa.fl_str_mv |
Productos Naturales Marinos |
| dc.subject.decs.none.fl_str_mv |
Animales Animals Productos Biológicos - aislamiento y purificación Biological Products - isolation y purification Productos Biológicos - farmacología Productos Biológicos - pharmacology Descubrimiento de Drogas Drug Discovery Océanos y Mares Oceans and Seas |
| topic |
Animales Animals Productos Biológicos - aislamiento y purificación Biological Products - isolation y purification Productos Biológicos - farmacología Productos Biológicos - pharmacology Descubrimiento de Drogas Drug Discovery Océanos y Mares Oceans and Seas |
| description |
ABSTRACT: Marine organisms represent a new extensive source for bioactive molecules. They have the potential to provide new therapeutic alternatives to treat human diseases. In this paper, we describe and discuss a variety of isolated and semisynthetic molecules obtained from marine phase II, phase III and at the commercialization stage of new drug development. A description of the mechanism of action, dosage used and side effects are also reported. The positive results obtained from these studies have triggered the development of new studies to evaluate the prospects for utilization of marine organisms. |
| publishDate |
2011 |
| dc.date.issued.none.fl_str_mv |
2011 |
| dc.date.accessioned.none.fl_str_mv |
2023-08-25T16:22:10Z |
| dc.date.available.none.fl_str_mv |
2023-08-25T16:22:10Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
| dc.type.coarversion.spa.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| status_str |
publishedVersion |
| dc.identifier.citation.spa.fl_str_mv |
Galeano, E., Rojas, J. J., & Martínez, A. (2011). Pharmacological developments obtained from marine natural products and current pipeline perspective. Natural product communications, 6(2), 287–300. |
| dc.identifier.issn.none.fl_str_mv |
1934-578X |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/36367 |
| dc.identifier.doi.none.fl_str_mv |
10.1177/1934578X1100600233 |
| dc.identifier.eissn.none.fl_str_mv |
1555-9475 |
| identifier_str_mv |
Galeano, E., Rojas, J. J., & Martínez, A. (2011). Pharmacological developments obtained from marine natural products and current pipeline perspective. Natural product communications, 6(2), 287–300. 1934-578X 10.1177/1934578X1100600233 1555-9475 |
| url |
https://hdl.handle.net/10495/36367 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Nat. Prod. Commun. |
| dc.relation.citationendpage.spa.fl_str_mv |
300 |
| dc.relation.citationissue.spa.fl_str_mv |
2 |
| dc.relation.citationstartpage.spa.fl_str_mv |
287 |
| dc.relation.citationvolume.spa.fl_str_mv |
6 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Natural product communications |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ |
| dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ |
| dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.extent.spa.fl_str_mv |
14 |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.spa.fl_str_mv |
SAGE Publications |
| dc.publisher.place.spa.fl_str_mv |
Westerville, Estados Unidos |
| institution |
Universidad de Antioquia |
| bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstreams/bfc6653d-6336-4e29-8392-1cc42e1d830a/download https://bibliotecadigital.udea.edu.co/bitstreams/5e9676a3-cc1c-49d3-b807-f318a4f6dfc6/download https://bibliotecadigital.udea.edu.co/bitstreams/7f8bbb83-679c-4d04-b164-09a12dc8bccf/download https://bibliotecadigital.udea.edu.co/bitstreams/7c961810-e8d2-4eab-9447-150063c388ad/download https://bibliotecadigital.udea.edu.co/bitstreams/ee231dec-e729-4e7d-b649-d29adb76b872/download |
| bitstream.checksum.fl_str_mv |
8a4605be74aa9ea9d79846c1fba20a33 869008968d4fc88f31c3f844c04301d9 c0c92b0ffc8b7d22d9cf56754a416a76 bf76cd388594d09ce70ecb4f036b18e7 1a01d565560b3c420bdea6d7bf80f325 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional de la Universidad de Antioquia |
| repository.mail.fl_str_mv |
aplicacionbibliotecadigitalbiblioteca@udea.edu.co |
| _version_ |
1851052282100056064 |
| spelling |
Galeano Jaramillo, Elkin de JesúsMartínez Martínez, AlejandroRojas, Jhon J.Productos Naturales Marinos2023-08-25T16:22:10Z2023-08-25T16:22:10Z2011Galeano, E., Rojas, J. J., & Martínez, A. (2011). Pharmacological developments obtained from marine natural products and current pipeline perspective. Natural product communications, 6(2), 287–300.1934-578Xhttps://hdl.handle.net/10495/3636710.1177/1934578X11006002331555-9475ABSTRACT: Marine organisms represent a new extensive source for bioactive molecules. They have the potential to provide new therapeutic alternatives to treat human diseases. In this paper, we describe and discuss a variety of isolated and semisynthetic molecules obtained from marine phase II, phase III and at the commercialization stage of new drug development. A description of the mechanism of action, dosage used and side effects are also reported. The positive results obtained from these studies have triggered the development of new studies to evaluate the prospects for utilization of marine organisms.COL001504314application/pdfengSAGE PublicationsWesterville, Estados Unidoshttp://creativecommons.org/licenses/by-nc/2.5/co/https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline PerspectivesArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAnimalesAnimalsProductos Biológicos - aislamiento y purificaciónBiological Products - isolation y purificationProductos Biológicos - farmacologíaProductos Biológicos - pharmacologyDescubrimiento de DrogasDrug DiscoveryOcéanos y MaresOceans and SeasNat. Prod. Commun.30022876Natural product communicationsPublicationLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/bfc6653d-6336-4e29-8392-1cc42e1d830a/download8a4605be74aa9ea9d79846c1fba20a33MD53falseAnonymousREADORIGINALGaleanoElkin_2011_Pharmacological_Developments.pdfGaleanoElkin_2011_Pharmacological_Developments.pdfArtículo de investigaciónapplication/pdf434363https://bibliotecadigital.udea.edu.co/bitstreams/5e9676a3-cc1c-49d3-b807-f318a4f6dfc6/download869008968d4fc88f31c3f844c04301d9MD51trueAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8933https://bibliotecadigital.udea.edu.co/bitstreams/7f8bbb83-679c-4d04-b164-09a12dc8bccf/downloadc0c92b0ffc8b7d22d9cf56754a416a76MD52falseAnonymousREADTEXTGaleanoElkin_2011_Pharmacological_Developments.pdf.txtGaleanoElkin_2011_Pharmacological_Developments.pdf.txtExtracted texttext/plain77187https://bibliotecadigital.udea.edu.co/bitstreams/7c961810-e8d2-4eab-9447-150063c388ad/downloadbf76cd388594d09ce70ecb4f036b18e7MD54falseAnonymousREADTHUMBNAILGaleanoElkin_2011_Pharmacological_Developments.pdf.jpgGaleanoElkin_2011_Pharmacological_Developments.pdf.jpgGenerated Thumbnailimage/jpeg17890https://bibliotecadigital.udea.edu.co/bitstreams/ee231dec-e729-4e7d-b649-d29adb76b872/download1a01d565560b3c420bdea6d7bf80f325MD55falseAnonymousREAD10495/36367oai:bibliotecadigital.udea.edu.co:10495/363672025-03-26 19:51:15.926http://creativecommons.org/licenses/by-nc/2.5/co/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.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 |
