Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspectives

ABSTRACT: Marine organisms represent a new extensive source for bioactive molecules. They have the potential to provide new therapeutic alternatives to treat human diseases. In this paper, we describe and discuss a variety of isolated and semisynthetic molecules obtained from marine phase II, phase III and at the commercialization stage of new drug development. A description of the mechanism of action, dosage used and side effects are also reported. The positive results obtained from these studies have triggered the development of new studies to evaluate the prospects for utilization of marine organisms.

• Autores: Galeano Jaramillo, Elkin de Jesús; Martínez Martínez, Alejandro; Rojas, Jhon J.
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2011
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/36367
• Acceso en línea: https://hdl.handle.net/10495/36367
• Palabra clave: Animales; Animals; Productos Biológicos - aislamiento y purificación; Biological Products - isolation y purification; Productos Biológicos - farmacología; Productos Biológicos - pharmacology; Descubrimiento de Drogas; Drug Discovery; Océanos y Mares; Oceans and Seas
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc/2.5/co/