The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies

ABSTRACT: Since the 1990s, the International Union of Immunological Societies (IUIS) PID expert committee (EC), now called Inborn Errors of Immunity Committee, has published every other year a classification of the inborn errors of immunity. This complete catalog serves as a reference for immunologists and researchers worldwide. However, it was unadapted for clinicians at the bedside. For those, the IUIS PID EC is now publishing a phenotypical classification since 2013, which proved to be more user-friendly. There are now 320 single-gene inborn errors of immunity underlying phenotypes as diverse as infection, malignancy, allergy, auto-immunity, and auto-inflammation. We herein propose the revised 2017 phenotypic classification, based on the accompanying 2017 IUIS Inborn Errors of Immunity Committee classification.

• Autores: Bousfiha, Aziz; Jeddane, Leïla; Picard, Capucine; Ailal, Fatima; Gaspar, H. Bobby; Franco Restrepo, José Luis
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2017
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/23080
• Acceso en línea: http://hdl.handle.net/10495/23080
• Palabra clave: Síndromes de Inmunodeficiencia; Immunologic Deficiency Syndromes; Clasificación; Classification; Phenotypic; Inborn errors of immunity; Unión Internacional de las Sociedades Inmunológicas (IUIS); Fenotípica
• Rights: openAccess
• License: https://creativecommons.org/licenses/by/4.0/