Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study

ABSTRACT: Objective: We aim to determine the prevalence of mental disorders in siblings of children with attention deficit hyperactivity disorder (ADHD), and to determine how psychosocial adversity factors relate to this psychopathology, in a low-middle income country (Colombia). Methods: We evaluat...

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Autores:
Aguirre Acevedo, Daniel Camilo
García Valencia, Jenny
Arcos Burgos, Oscar Mauricio
López Jaramillo, Carlos
Palacio Ortiz, Juan David
Gómez Álzate, Alejandra María
Hidalgo López, Catalina
Martínez Zamora, Marta
Cuartas Arias, Mauricio
Tipo de recurso:
Article of investigation
Fecha de publicación:
2023
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/44730
Acceso en línea:
https://hdl.handle.net/10495/44730
Palabra clave:
Hermanos
Siblings
Estudios Transversales
Cross-Sectional Studies
Trastorno por Déficit de Atención con Hiperactividad
Attention Deficit Disorder with Hyperactivity
Impacto Psicosocial
Psychosocial Impact
Niño
Child
Adolescente
Adolescent
https://id.nlm.nih.gov/mesh/D002648
https://id.nlm.nih.gov/mesh/D035781
https://id.nlm.nih.gov/mesh/D003430
https://id.nlm.nih.gov/mesh/D001289
https://id.nlm.nih.gov/mesh/D000293
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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repository_id_str
dc.title.spa.fl_str_mv Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
dc.title.translated.spa.fl_str_mv Riesgo psicopatológico en hermanos de sujetos con trastorno por déficit de atención con hiperactividad: Estudio transversal
title Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
spellingShingle Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
Hermanos
Siblings
Estudios Transversales
Cross-Sectional Studies
Trastorno por Déficit de Atención con Hiperactividad
Attention Deficit Disorder with Hyperactivity
Impacto Psicosocial
Psychosocial Impact
Niño
Child
Adolescente
Adolescent
https://id.nlm.nih.gov/mesh/D002648
https://id.nlm.nih.gov/mesh/D035781
https://id.nlm.nih.gov/mesh/D003430
https://id.nlm.nih.gov/mesh/D001289
https://id.nlm.nih.gov/mesh/D000293
title_short Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
title_full Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
title_fullStr Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
title_full_unstemmed Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
title_sort Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study
dc.creator.fl_str_mv Aguirre Acevedo, Daniel Camilo
García Valencia, Jenny
Arcos Burgos, Oscar Mauricio
López Jaramillo, Carlos
Palacio Ortiz, Juan David
Gómez Álzate, Alejandra María
Hidalgo López, Catalina
Martínez Zamora, Marta
Cuartas Arias, Mauricio
dc.contributor.author.none.fl_str_mv Aguirre Acevedo, Daniel Camilo
García Valencia, Jenny
Arcos Burgos, Oscar Mauricio
López Jaramillo, Carlos
Palacio Ortiz, Juan David
Gómez Álzate, Alejandra María
Hidalgo López, Catalina
Martínez Zamora, Marta
Cuartas Arias, Mauricio
dc.contributor.researchgroup.spa.fl_str_mv Grupo Académico de Epidemiología Clínica
Grupo de Investigación en Psiquiatría GIPSI
dc.subject.decs.none.fl_str_mv Hermanos
Siblings
Estudios Transversales
Cross-Sectional Studies
Trastorno por Déficit de Atención con Hiperactividad
Attention Deficit Disorder with Hyperactivity
Impacto Psicosocial
Psychosocial Impact
Niño
Child
Adolescente
Adolescent
topic Hermanos
Siblings
Estudios Transversales
Cross-Sectional Studies
Trastorno por Déficit de Atención con Hiperactividad
Attention Deficit Disorder with Hyperactivity
Impacto Psicosocial
Psychosocial Impact
Niño
Child
Adolescente
Adolescent
https://id.nlm.nih.gov/mesh/D002648
https://id.nlm.nih.gov/mesh/D035781
https://id.nlm.nih.gov/mesh/D003430
https://id.nlm.nih.gov/mesh/D001289
https://id.nlm.nih.gov/mesh/D000293
dc.subject.lcshuri.none.fl_str_mv https://id.nlm.nih.gov/mesh/D002648
dc.subject.meshuri.none.fl_str_mv https://id.nlm.nih.gov/mesh/D035781
https://id.nlm.nih.gov/mesh/D003430
https://id.nlm.nih.gov/mesh/D001289
https://id.nlm.nih.gov/mesh/D000293
description ABSTRACT: Objective: We aim to determine the prevalence of mental disorders in siblings of children with attention deficit hyperactivity disorder (ADHD), and to determine how psychosocial adversity factors relate to this psychopathology, in a low-middle income country (Colombia). Methods: We evaluated subjects with ADHD diagnosed according to the DSM-5 criteria, one of their parents and one of their siblings (ages 8-19). We used the ADHD rating scale and a set of instruments to assess the presence of mental disorders as well as psychosocial adversity. Results: We evaluated 74 trios formed by the index case with ADHD, one sibling and one of the parents. We found that 24.3% of the participating siblings also met the criteria for ADHD and another 24.3% for other psychiatric disorders. The risk of these siblings having ADHD increased further when one of the parents reported a history of ADHD. We also found that 28.3% of the families faced high levels of psychosocial adversity as per their scores in the Rutter Adversity Index. Conclusions: Siblings of subjects with ADHD showed a significant risk for ADHD and other mental disorders. That risk increased if a parent reported a history of ADHD and also when two or more psychosocial adversity factors were present. This study supports the importance of early detection in efforts to decrease the risk for other siblings.
publishDate 2023
dc.date.issued.none.fl_str_mv 2023
dc.date.accessioned.none.fl_str_mv 2025-02-05T23:04:09Z
dc.date.available.none.fl_str_mv 2025-02-05T23:04:09Z
dc.type.spa.fl_str_mv Artículo de investigación
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.redcol.spa.fl_str_mv https://purl.org/redcol/resource_type/ART
dc.type.coarversion.spa.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
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dc.identifier.citation.spa.fl_str_mv Gómez-Álzate AM, Hidalgo-López C, García-Valencia J, Martínez-Zamora M, Aguirre-Acevedo DC, Cuartas-Arias M, Arcos-Burgos M, Valencia-Evhecerry J, Lopez-Jaramillo C, Palacio-Ortiz JD. Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study. Rev Colomb Psiquiatr (Engl Ed). 2023 Jul-Sep;52(3):193-200. English, Spanish. doi: 10.1016/j.rcpeng.2021.03.006. PMID: 37923415.
dc.identifier.issn.none.fl_str_mv 0034-7450
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10495/44730
dc.identifier.doi.none.fl_str_mv 10.1016/j.rcp.2021.03.007
dc.identifier.eissn.none.fl_str_mv 2530-3139
identifier_str_mv Gómez-Álzate AM, Hidalgo-López C, García-Valencia J, Martínez-Zamora M, Aguirre-Acevedo DC, Cuartas-Arias M, Arcos-Burgos M, Valencia-Evhecerry J, Lopez-Jaramillo C, Palacio-Ortiz JD. Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study. Rev Colomb Psiquiatr (Engl Ed). 2023 Jul-Sep;52(3):193-200. English, Spanish. doi: 10.1016/j.rcpeng.2021.03.006. PMID: 37923415.
0034-7450
10.1016/j.rcp.2021.03.007
2530-3139
url https://hdl.handle.net/10495/44730
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Rev. Colomb. Psiquiatr.
dc.relation.citationendpage.spa.fl_str_mv 200
dc.relation.citationissue.spa.fl_str_mv 3
dc.relation.citationstartpage.spa.fl_str_mv 193
dc.relation.citationvolume.spa.fl_str_mv 52
dc.relation.ispartofjournal.spa.fl_str_mv Revista Colombiana de Psiquiatría
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.publisher.spa.fl_str_mv Asociación Colombiana de Psiquiatría
dc.publisher.place.spa.fl_str_mv Bogotá, Colombia
institution Universidad de Antioquia
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spelling Aguirre Acevedo, Daniel CamiloGarcía Valencia, JennyArcos Burgos, Oscar MauricioLópez Jaramillo, CarlosPalacio Ortiz, Juan DavidGómez Álzate, Alejandra MaríaHidalgo López, CatalinaMartínez Zamora, MartaCuartas Arias, MauricioGrupo Académico de Epidemiología ClínicaGrupo de Investigación en Psiquiatría GIPSI2025-02-05T23:04:09Z2025-02-05T23:04:09Z2023Gómez-Álzate AM, Hidalgo-López C, García-Valencia J, Martínez-Zamora M, Aguirre-Acevedo DC, Cuartas-Arias M, Arcos-Burgos M, Valencia-Evhecerry J, Lopez-Jaramillo C, Palacio-Ortiz JD. Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional Study. Rev Colomb Psiquiatr (Engl Ed). 2023 Jul-Sep;52(3):193-200. English, Spanish. doi: 10.1016/j.rcpeng.2021.03.006. PMID: 37923415.0034-7450https://hdl.handle.net/10495/4473010.1016/j.rcp.2021.03.0072530-3139ABSTRACT: Objective: We aim to determine the prevalence of mental disorders in siblings of children with attention deficit hyperactivity disorder (ADHD), and to determine how psychosocial adversity factors relate to this psychopathology, in a low-middle income country (Colombia). Methods: We evaluated subjects with ADHD diagnosed according to the DSM-5 criteria, one of their parents and one of their siblings (ages 8-19). We used the ADHD rating scale and a set of instruments to assess the presence of mental disorders as well as psychosocial adversity. Results: We evaluated 74 trios formed by the index case with ADHD, one sibling and one of the parents. We found that 24.3% of the participating siblings also met the criteria for ADHD and another 24.3% for other psychiatric disorders. The risk of these siblings having ADHD increased further when one of the parents reported a history of ADHD. We also found that 28.3% of the families faced high levels of psychosocial adversity as per their scores in the Rutter Adversity Index. Conclusions: Siblings of subjects with ADHD showed a significant risk for ADHD and other mental disorders. That risk increased if a parent reported a history of ADHD and also when two or more psychosocial adversity factors were present. This study supports the importance of early detection in efforts to decrease the risk for other siblings.RESUMEN: Objetivo: Nuestro objetivo es determinar la prevalencia de trastornos mentales en hermanos de casos con TDAH y cómo los factores de adversidad psicosocial se relacionan con esta psicopatología en un país de ingresos bajos-medios (Colombia). Métodos: Se evaluó a sujetos con TDAH diagnosticado según los criterios del DSM-5, uno de sus padres y uno de sus hermanos (edades, 8-19 años). Mediante la escala de calificación del ˜ TDAH y un conjunto de otros instrumentos se evaluó la presencia de trastornos mentales y adversidad psicosocial. Resultados: Se evaluó a 74 tríos formados por el caso índice con TDAH, un hermano y uno de los padres. Se halló que un 24,3% de los hermanos participantes también cumplían los criterios de TDAH y otro 24,3%, otros trastornos psiquiátricos. El riesgo de que estos hermanos tuvieran TDAH aumentó aún más cuando uno de los padres informó antecedentes de TDAH. También, que el 28,3% de las familias se enfrentaron a altos niveles de adversidad psicosocial según sus puntuaciones en el Índice de Adversidad de Rutter. Conclusiones: Los hermanos de sujetos con TDAH mostraron un significativo riesgo de TDAH y otros trastornos mentales. Ese riesgo aumenta si uno de los padres reporta antecedentes de TDAH y también cuando se presentan 2 o más factores de adversidad psicosocial. Este estudio respalda la importancia de la detección temprana con el fin de disminuir el riesgo para otros hermanos.Universidad de Antioquia. Vicerrectoría de investigación. Comité para el Desarrollo de la Investigación - CODIColombia. Ministerio de Ciencia, Tecnología e Innovación - MinCienciasCOL0007121COL00291478 páginasapplication/pdfengAsociación Colombiana de PsiquiatríaBogotá, Colombiahttp://creativecommons.org/licenses/by-nc-nd/2.5/co/https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Psychopathological Risk in Siblings of Subjects with Attention-Deficit/Hyperactivity Disorder: A cross-Sectional StudyRiesgo psicopatológico en hermanos de sujetos con trastorno por déficit de atención con hiperactividad: Estudio transversalArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionHermanosSiblingsEstudios TransversalesCross-Sectional StudiesTrastorno por Déficit de Atención con HiperactividadAttention Deficit Disorder with HyperactivityImpacto PsicosocialPsychosocial ImpactNiñoChildAdolescenteAdolescenthttps://id.nlm.nih.gov/mesh/D002648https://id.nlm.nih.gov/mesh/D035781https://id.nlm.nih.gov/mesh/D003430https://id.nlm.nih.gov/mesh/D001289https://id.nlm.nih.gov/mesh/D000293Rev. Colomb. Psiquiatr.200319352Revista Colombiana de PsiquiatríaFactores de adversidad psicosocial, genética y clínica asociada al TDAH en hermanos en alto riesgoCaracterísticas clínicas, marcadores genéticos, y factores de adversidad psicosocial que predicen Trastorno por Déficit de atención con Hiperactividad (TDAH) en hermanos de alto riesgoCODI 2017-16250MinCiencias 111577757629RoR:03bp5hc83RoR:03fd5ne08PublicationCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8823https://bibliotecadigital.udea.edu.co/bitstreams/bb962511-f083-4163-9edb-6b65ec6af91a/downloadb88b088d9957e670ce3b3fbe2eedbc13MD52falseAnonymousREADORIGINALGomezAlejandra_2023_Psychopathological_Risk_Siblings.pdfGomezAlejandra_2023_Psychopathological_Risk_Siblings.pdfArtículo de investigaciónapplication/pdf723844https://bibliotecadigital.udea.edu.co/bitstreams/80d5c3fe-ed90-47e6-b00b-e15bbe591b86/download66cc8f85dcdfe9a4a22a62458da58f63MD51trueAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/1f09b103-f426-463e-afbf-de6b165816c6/download8a4605be74aa9ea9d79846c1fba20a33MD53falseAnonymousREADTEXTGomezAlejandra_2023_Psychopathological_Risk_Siblings.pdf.txtGomezAlejandra_2023_Psychopathological_Risk_Siblings.pdf.txtExtracted texttext/plain37990https://bibliotecadigital.udea.edu.co/bitstreams/d979aad2-6b77-4f62-9fdf-ce49c9f75555/download56eafc8f38065db8bf888cb4c474d800MD58falseAnonymousREADTHUMBNAILGomezAlejandra_2023_Psychopathological_Risk_Siblings.pdf.jpgGomezAlejandra_2023_Psychopathological_Risk_Siblings.pdf.jpgGenerated Thumbnailimage/jpeg14251https://bibliotecadigital.udea.edu.co/bitstreams/a4f01810-446e-4ba7-9847-158fb75cc96c/downloadf361dc5d2f8122068b4dd654cd012372MD59falseAnonymousREAD10495/44730oai:bibliotecadigital.udea.edu.co:10495/447302025-03-26 17:11:58.019http://creativecommons.org/licenses/by-nc-nd/2.5/co/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.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