Rotenone Induces a Neuropathological Phenotype in Cholinergic‑like Neurons Resembling Parkinson’s Disease Dementia (PDD)

ABSTRACT: Parkinson's disease with dementia (PDD) is a neurological disorder that clinically and neuropathologically overlaps with Parkinson's disease (PD) and Alzheimer's disease (AD). Although it is assumed that alpha-synuclein (α -Syn), amyloid beta (Aβ), and the protein Tau might...

Full description

Autores:

Giraldo Berrío, Daniela
Mendívil Pérez, Miguel Ángel
Vélez Pardo, Carlos Alberto
Jiménez del Río, Marlene

Tipo de recurso:

Article of investigation

Fecha de publicación:

2024

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39783

Acceso en línea:

https://hdl.handle.net/10495/39783

Palabra clave:

alfa-Sinucleína
alpha-Synuclein
Rotenona
Rotenone
Células Cultivadas
Cells, Cultured
Neuronas Colinérgicas
Cholinergic Neurons
Metabolismo
Metabolism
Patología
Pathology
Demencia
Dementia
Enfermedad de Parkinson
Parkinson Disease
Especies Reactivas de Oxígeno
Reactive Oxygen Species
Fenotipo
Phenotype
https://id.nlm.nih.gov/mesh/D051844
https://id.nlm.nih.gov/mesh/D012402
https://id.nlm.nih.gov/mesh/D002478
https://id.nlm.nih.gov/mesh/D059329
https://id.nlm.nih.gov/mesh/D008660
https://id.nlm.nih.gov/mesh/D010336
https://id.nlm.nih.gov/mesh/D003704
https://id.nlm.nih.gov/mesh/D010300
https://id.nlm.nih.gov/mesh/D017382
https://id.nlm.nih.gov/mesh/D010641

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/