Subjective Cognitive and Communicative Complaints and Health-Related Quality of Life in Parkinson's Disease with and without Mild Cognitive Impairment

Introduction: Mild Cognitive Impairment (MCI) is common in Parkinson's Disease (PD). Few studies have compared the Health-Related Quality of Life (HRQoL) in patients with and without MCI due to PD (PD-MCI), and its correlation to patients’ subjective cognitive and communicative difficulties has not been explored. Objective: We aimed to compare HRQoL in PD-MCI and PD without MCI (PD-nMCI), and explore its possible relationship to subjective cognitive and communicative complaints. Methods: We included 29 PD-nMCI and 11 PD-MCI patients. The HRQoL was assessed with the Parkinson's Disease Questionnaire-39 (PDQ-39): its Cognition dimension was used as a measure of subjective cognitive complaints, its Communication dimension for subjective communicative complaints, and the summary index (PDQ-39 SI) as an indicator of HRQoL. Non-parametric partial correlations between the Cognition and Communication dimensions, and the adjusted PDQ-39 SI were conducted. Results: PD-MCI patients had greater subjective cognitive and communicative complaints and worse HRQoL than PD-nMCI patients. In the PD-MCI group, both subjective cognitive and communicative complaints exhibited significant direct correlations with the adjusted HRQoL scores. Conclusions: HRQoL seems to be affected in PD-MCI, and it might be influenced by greater subjective cognitive and communicative complaints. Including patient-reported outcome measures of HRQoL, and providing cognitive and speech rehabilitation, as well as psychotherapeutic strategies to face these deficits can enhance the patient-centred approach in PD.

• Autores: Jaramillo Jiménez, Alberto; Bocanegra García, Orfa Yamile; Buriticá Henao, Omar Fredy; Pineda Salazar, David Antonio; Moreno Gómez, Leonardo; Tobón Quintero, Carlos Andrés; Aguirre Acevedo, Daniel Camilo; Sierra Castrillón, Melissa; Vásquez Botero, Daniel; Vélez Hernández, Juan Esteban; Borda Borda, Miguel Germán; García Cifuentes, Elkin Román; Aguillón Niño, David Fernando; Madrigal Zapata, Lucía del Socorro; Aarslanda, Dag; Lopera Restrepo, Francisco Javier
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2023
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/45790
• Acceso en línea: https://hdl.handle.net/10495/45790
• Palabra clave: Enfermedad de Parkinson; Parkinson Disease; Calidad de Vida; Quality of Life; Disfunción Cognitiva; Cognitive Dysfunction; Enfermedades Neurodegenerativas; Neurodegenerative Diseases; Trastornos del Movimiento; Movement Disorders; https://id.nlm.nih.gov/mesh/D010300; https://id.nlm.nih.gov/mesh/D011788; https://id.nlm.nih.gov/mesh/D060825; https://id.nlm.nih.gov/mesh/D019636; https://id.nlm.nih.gov/mesh/D009069; ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc-nd/4.0/