Growing Incidence of Thyroid Carcinoma in recent years : Factors underlying Overdiagnosis

ABSTRACT: There is an increasing incidence of well-differentiated thyroid cancer worldwide. Much of the increase is secondary to increased detection of small, low-risk tumors, with questionable clinical significance. This review addresses the factors that contribute to the increasing incidence and c...

Full description

Autores:
Sanabria Quiroga, Álvaro Enrique
Kowalski, Luiz Paulo
Shah, Jatin P
Nixon, Iain James
Angelos, Peter
Williams, Michelle D
Rinaldo, Alessandra
Ferlito, Alfio
Tipo de recurso:
Review article
Fecha de publicación:
2018
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/33298
Acceso en línea:
https://hdl.handle.net/10495/33298
https://onlinelibrary.wiley.com/doi/10.1002/hed.25029
Palabra clave:
Incidence
Incidencia
Medical Overuse
Uso Excesivo de los Servicios de Salud
Screening
diagnóstico
Thyroid Neoplasms
Neoplasias de la Tiroides
Overdiagnosis
Sobrediagnóstico
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
Description
Summary:ABSTRACT: There is an increasing incidence of well-differentiated thyroid cancer worldwide. Much of the increase is secondary to increased detection of small, low-risk tumors, with questionable clinical significance. This review addresses the factors that contribute to the increasing incidence and considers environmental, and patient-based and clinician-led influences. Articles addressing the causes of the increased incidence were critically reviewed. A complex interplay of environmental, medical, and social pressures has resulted in increased awareness of the thyroid disease risk, increased screening of thyroid cancers, and increased diagnosis of thyroid cancers. Although there is evidence to suggest that the true disease incidence may be changing slightly, most of the increase is related to factors that promote early diagnosis of low-risk lesions, which is resulting in a significant phenomenon of overdiagnosis. An improved understanding of these pressures at a global level will enable healthcare policymakers to react appropriately to this challenge in the future.