In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives
ABSTRACT: The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be consider...
- Autores:
-
Robledo Restrepo, Sara María
Osorio Durango, Edison
Muñoz Herrera, Diana Lorena
Jaramillo Pérez, Luz Marina
Restrepo Agudelo, Adriana María
Arango Acosta, Gabriel Jaime
Vélez Bernal, Iván Darío
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2005
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/24198
- Acceso en línea:
- http://hdl.handle.net/10495/24198
- Palabra clave:
- Timol
Thymol
Citotoxicidad
Cytotoxicity
http://aims.fao.org/aos/agrovoc/c_34251
- Rights
- openAccess
- License
- Derechos reservados - Está prohibida la reproducción parcial o total de esta publicación
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|
| dc.title.spa.fl_str_mv |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives |
| title |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives |
| spellingShingle |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives Timol Thymol Citotoxicidad Cytotoxicity http://aims.fao.org/aos/agrovoc/c_34251 |
| title_short |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives |
| title_full |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives |
| title_fullStr |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives |
| title_full_unstemmed |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives |
| title_sort |
In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives |
| dc.creator.fl_str_mv |
Robledo Restrepo, Sara María Osorio Durango, Edison Muñoz Herrera, Diana Lorena Jaramillo Pérez, Luz Marina Restrepo Agudelo, Adriana María Arango Acosta, Gabriel Jaime Vélez Bernal, Iván Darío |
| dc.contributor.author.none.fl_str_mv |
Robledo Restrepo, Sara María Osorio Durango, Edison Muñoz Herrera, Diana Lorena Jaramillo Pérez, Luz Marina Restrepo Agudelo, Adriana María Arango Acosta, Gabriel Jaime Vélez Bernal, Iván Darío |
| dc.contributor.researchgroup.spa.fl_str_mv |
Grupo de Investigación en Sustancias Bioactivas (GISB) Programa de Estudio y Control de Enfermedades Tropicales (PECET) |
| dc.subject.decs.none.fl_str_mv |
Timol Thymol |
| topic |
Timol Thymol Citotoxicidad Cytotoxicity http://aims.fao.org/aos/agrovoc/c_34251 |
| dc.subject.agrovoc.none.fl_str_mv |
Citotoxicidad Cytotoxicity |
| dc.subject.agrovocuri.none.fl_str_mv |
http://aims.fao.org/aos/agrovoc/c_34251 |
| description |
ABSTRACT: The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be considered as new lead structures in the search for novel antileishmanial drugs. |
| publishDate |
2005 |
| dc.date.issued.none.fl_str_mv |
2005 |
| dc.date.accessioned.none.fl_str_mv |
2021-11-18T00:27:48Z |
| dc.date.available.none.fl_str_mv |
2021-11-18T00:27:48Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
| dc.type.coarversion.spa.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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publishedVersion |
| dc.identifier.citation.spa.fl_str_mv |
Robledo, S., Osorio, E., Muñoz, D., Jaramillo, L. M., Restrepo, A., Arango, G., & Vélez, I. (2005). In vitro and in vivo cytotoxicities and antileishmanial activities of thymol and hemisynthetic derivatives. Antimicrobial agents and chemotherapy, 49(4), 1652–1655. https://doi.org/10.1128/AAC.49.4.1652-1655.2005 |
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0066-4804 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/24198 |
| dc.identifier.doi.none.fl_str_mv |
10.1128/AAC.49.4.1652-1655.2005 |
| dc.identifier.eissn.none.fl_str_mv |
1098-6596 |
| identifier_str_mv |
Robledo, S., Osorio, E., Muñoz, D., Jaramillo, L. M., Restrepo, A., Arango, G., & Vélez, I. (2005). In vitro and in vivo cytotoxicities and antileishmanial activities of thymol and hemisynthetic derivatives. Antimicrobial agents and chemotherapy, 49(4), 1652–1655. https://doi.org/10.1128/AAC.49.4.1652-1655.2005 0066-4804 10.1128/AAC.49.4.1652-1655.2005 1098-6596 |
| url |
http://hdl.handle.net/10495/24198 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Antimicrob. Agents Chemother. |
| dc.relation.citationendpage.spa.fl_str_mv |
1655 |
| dc.relation.citationissue.spa.fl_str_mv |
4 |
| dc.relation.citationstartpage.spa.fl_str_mv |
1652 |
| dc.relation.citationvolume.spa.fl_str_mv |
49 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Antimicrobial Agents and Chemotherapy |
| dc.rights.uri.spa.fl_str_mv |
Derechos reservados - Está prohibida la reproducción parcial o total de esta publicación |
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info:eu-repo/semantics/openAccess |
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http://purl.org/coar/access_right/c_abf2 |
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Derechos reservados - Está prohibida la reproducción parcial o total de esta publicación http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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4 |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
American Society for Microbiology |
| dc.publisher.place.spa.fl_str_mv |
Washington, Estados Unidos |
| institution |
Universidad de Antioquia |
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Robledo Restrepo, Sara MaríaOsorio Durango, EdisonMuñoz Herrera, Diana LorenaJaramillo Pérez, Luz MarinaRestrepo Agudelo, Adriana MaríaArango Acosta, Gabriel JaimeVélez Bernal, Iván DaríoGrupo de Investigación en Sustancias Bioactivas (GISB)Programa de Estudio y Control de Enfermedades Tropicales (PECET)2021-11-18T00:27:48Z2021-11-18T00:27:48Z2005Robledo, S., Osorio, E., Muñoz, D., Jaramillo, L. M., Restrepo, A., Arango, G., & Vélez, I. (2005). In vitro and in vivo cytotoxicities and antileishmanial activities of thymol and hemisynthetic derivatives. Antimicrobial agents and chemotherapy, 49(4), 1652–1655. https://doi.org/10.1128/AAC.49.4.1652-1655.20050066-4804http://hdl.handle.net/10495/2419810.1128/AAC.49.4.1652-1655.20051098-6596ABSTRACT: The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be considered as new lead structures in the search for novel antileishmanial drugs.COL0010359COL00150994application/pdfengAmerican Society for MicrobiologyWashington, Estados UnidosDerechos reservados - Está prohibida la reproducción parcial o total de esta publicacióninfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic DerivativesArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionTimolThymolCitotoxicidadCytotoxicityhttp://aims.fao.org/aos/agrovoc/c_34251Antimicrob. 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