Mutations modifying sporadic Alzheimer's disease age of onset

ABSTRACT: The identification of mutations modifying the age of onset (AOO) in Alzheimer’s disease (AD) is crucial for understanding the natural history of AD and, therefore, for early interventions. Patients with sporadic AD (sAD) from a genetic isolate in the extremes of the AOO distribution were w...

Full description

Autores:

Lopera Restrepo, Francisco Javier
Vélez Valbuena, Jorge Iván
Hardip, Patel
Angad, Johar
Cai, Yeping
Rivera D., Dora
Tobón Quintero, Carlos Andrés
Villegas, Andrés
Sepúlveda Falla, Diego
Lehmann, Shaun
Easteal, Simon
Mastronardi, Claudio
Arcos Burgos, Oscar Mauricio

Tipo de recurso:

Article of investigation

Fecha de publicación:

2016

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/35187

Acceso en línea:

https://hdl.handle.net/10495/35187

Palabra clave:

Enfermedad de Alzheimer
Alzheimer Disease
Fenotipo
Phenotype
Mutación
Mutation
Genotipo
Genotype
Exoma
Exome
Genes Modificadores
Genes, Modifier

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/