Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evalua...
- Autores:
-
Herrera Mejía, Julián
Zapata Builes, Wildeman
Gaitán Charry, Diego Alejandro
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/21387
- Acceso en línea:
- http://hdl.handle.net/10495/21387
- Palabra clave:
- Hierro
Iron
Expresión Génica
Gene Expression
Calcio
Calcium
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc/4.0/
| id |
UDEA2_c36637002eafeb85303a4422436b1c9d |
|---|---|
| oai_identifier_str |
oai:bibliotecadigital.udea.edu.co:10495/21387 |
| network_acronym_str |
UDEA2 |
| network_name_str |
Repositorio UdeA |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells |
| title |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells |
| spellingShingle |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells Hierro Iron Expresión Génica Gene Expression Calcio Calcium |
| title_short |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells |
| title_full |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells |
| title_fullStr |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells |
| title_full_unstemmed |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells |
| title_sort |
Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells |
| dc.creator.fl_str_mv |
Herrera Mejía, Julián Zapata Builes, Wildeman Gaitán Charry, Diego Alejandro |
| dc.contributor.author.none.fl_str_mv |
Herrera Mejía, Julián Zapata Builes, Wildeman Gaitán Charry, Diego Alejandro |
| dc.contributor.researchgroup.spa.fl_str_mv |
Alimentación y Nutrición Humana |
| dc.subject.decs.none.fl_str_mv |
Hierro Iron Expresión Génica Gene Expression |
| topic |
Hierro Iron Expresión Génica Gene Expression Calcio Calcium |
| dc.subject.lemb.none.fl_str_mv |
Calcio Calcium |
| description |
ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evaluating this effect is the human cell line Caco-2, which is easy to use and produces results that strongly correlate with the absorption of iron in humans. |
| publishDate |
2016 |
| dc.date.issued.none.fl_str_mv |
2016 |
| dc.date.accessioned.none.fl_str_mv |
2021-08-01T17:50:36Z |
| dc.date.available.none.fl_str_mv |
2021-08-01T17:50:36Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
| dc.type.coarversion.spa.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| status_str |
publishedVersion |
| dc.identifier.issn.none.fl_str_mv |
0892-6638 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/21387 |
| dc.identifier.doi.none.fl_str_mv |
10.1096/fasebj.30.1_supplement.1173.1 |
| dc.identifier.eissn.none.fl_str_mv |
1530-6860 |
| identifier_str_mv |
0892-6638 10.1096/fasebj.30.1_supplement.1173.1 1530-6860 |
| url |
http://hdl.handle.net/10495/21387 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
FASEB J |
| dc.relation.citationendpage.spa.fl_str_mv |
2 |
| dc.relation.citationissue.spa.fl_str_mv |
Suplemento 1 |
| dc.relation.citationstartpage.spa.fl_str_mv |
1 |
| dc.relation.citationvolume.spa.fl_str_mv |
30 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
FASEB Journal |
| dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ |
| dc.rights.uri.*.fl_str_mv |
https://creativecommons.org/licenses/by-nc/2.5/co/ |
| dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/2.5/co/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.extent.spa.fl_str_mv |
2 |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.spa.fl_str_mv |
Federation of American Society of Experimental Biology (FASEB) |
| dc.publisher.place.spa.fl_str_mv |
Bethesda, Estados Unidos |
| institution |
Universidad de Antioquia |
| bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstreams/913c8286-eb86-465e-a448-9836206bfc17/download https://bibliotecadigital.udea.edu.co/bitstreams/3c8b177b-cdf6-4b1a-974a-f3b3e94fa9d8/download https://bibliotecadigital.udea.edu.co/bitstreams/c81b2154-627a-47da-9038-a21f7dc9d87a/download https://bibliotecadigital.udea.edu.co/bitstreams/bef4951c-03a9-4f78-a151-8fcc70fccfe6/download |
| bitstream.checksum.fl_str_mv |
48a205252c74f7b99ffe8dd585c08faf 8a4605be74aa9ea9d79846c1fba20a33 9b6159d8b9c7966c68b772fffd16790f cba9f52541ef529e8f3aceeb99311538 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional de la Universidad de Antioquia |
| repository.mail.fl_str_mv |
aplicacionbibliotecadigitalbiblioteca@udea.edu.co |
| _version_ |
1851052143832727552 |
| spelling |
Herrera Mejía, JuliánZapata Builes, WildemanGaitán Charry, Diego AlejandroAlimentación y Nutrición Humana2021-08-01T17:50:36Z2021-08-01T17:50:36Z20160892-6638http://hdl.handle.net/10495/2138710.1096/fasebj.30.1_supplement.1173.11530-6860ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evaluating this effect is the human cell line Caco-2, which is easy to use and produces results that strongly correlate with the absorption of iron in humans.COL00004072application/pdfengFederation of American Society of Experimental Biology (FASEB)Bethesda, Estados Unidoshttps://creativecommons.org/licenses/by-nc/4.0/https://creativecommons.org/licenses/by-nc/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cellsArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionHierroIronExpresión GénicaGene ExpressionCalcioCalciumFASEB J2Suplemento 1130FASEB JournalPublicationORIGINALHerreraJulian_2016_CalciumEffectGene.pdfHerreraJulian_2016_CalciumEffectGene.pdfArtículo de investigaciónapplication/pdf77559https://bibliotecadigital.udea.edu.co/bitstreams/913c8286-eb86-465e-a448-9836206bfc17/download48a205252c74f7b99ffe8dd585c08fafMD51trueAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/3c8b177b-cdf6-4b1a-974a-f3b3e94fa9d8/download8a4605be74aa9ea9d79846c1fba20a33MD52falseAnonymousREADTEXTHerreraJulian_2016_CalciumEffectGene.pdf.txtHerreraJulian_2016_CalciumEffectGene.pdf.txtExtracted texttext/plain2883https://bibliotecadigital.udea.edu.co/bitstreams/c81b2154-627a-47da-9038-a21f7dc9d87a/download9b6159d8b9c7966c68b772fffd16790fMD55falseAnonymousREADTHUMBNAILHerreraJulian_2016_CalciumEffectGene.pdf.jpgHerreraJulian_2016_CalciumEffectGene.pdf.jpgGenerated Thumbnailimage/jpeg12588https://bibliotecadigital.udea.edu.co/bitstreams/bef4951c-03a9-4f78-a151-8fcc70fccfe6/downloadcba9f52541ef529e8f3aceeb99311538MD56falseAnonymousREAD10495/21387oai:bibliotecadigital.udea.edu.co:10495/213872025-03-26 17:38:20.569https://creativecommons.org/licenses/by-nc/4.0/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.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 |