Quercetin ameliorates inflammation in CA1 hippocampal region in aged triple transgenic Alzheimer´s disease mice model
ABSTRACT: Alzheimer’s disease is the most common form of dementia. It is characterized by histopathological hallmarks such as senile plaques and neurofibrillary tangles, as well as a concomitant activation of microglial cells and astrocytes that release pro-inflammatory mediators such as IL-1β, iNOS...
- Autores:
-
Sabogal Guáqueta, Angélica María
Cardona Gómez, Gloria Patricia
Vargas Restrepo, Felipe
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/36523
- Acceso en línea:
- https://hdl.handle.net/10495/36523
- Palabra clave:
- Enfermedad de Alzheimer
Alzheimer Disease
Quercetina
Quercetin
Microglía
Astrocitos
Astrocytes
Demencia
Dementia
Región CA1 Hipocampal
CA1 Region, Hippocampal
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/
| Summary: | ABSTRACT: Alzheimer’s disease is the most common form of dementia. It is characterized by histopathological hallmarks such as senile plaques and neurofibrillary tangles, as well as a concomitant activation of microglial cells and astrocytes that release pro-inflammatory mediators such as IL-1β, iNOS, and COX-2, leading to neuronal dysfunction and death. |
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