Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response
ABSTRACT: Calcium phosphates are biomaterials widely used in bone tissue engineering. In recent years, the alternative of obtaining these materials with antimicrobial properties, has been explored due to the multiple advantages that this would imply in the design of devices or implants that prevent...
- Autores:
-
Robledo Restrepo, Sara María
Ospina Aristizábal, Victoria Eugenia
Lopera Sepúlveda, Alex Arbey
Zutta Villate, Julián Mateo
Gómez Zapata, Adrián
Puerta Ortiz, Jorge Anselmo
Chavarriaga Miranda, Edgar Andrés
Bezzon, Vinicius D.N.
Paucar Álvarez, Carlos Guillermo
García García, Claudia Patricia
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2022
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/44298
- Acceso en línea:
- https://hdl.handle.net/10495/44298
- Palabra clave:
- Fosfatos de Calcio
Calcium Phosphates
Nanopartículas del Metal
Metal Nanoparticles
Antiinfecciosos
Anti-Infective Agents
Ingeniería de Tejidos
Tissue Engineering
https://id.nlm.nih.gov/mesh/D002130
https://id.nlm.nih.gov/mesh/D053768
https://id.nlm.nih.gov/mesh/D000890
https://id.nlm.nih.gov/mesh/D023822
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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| dc.title.spa.fl_str_mv |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response |
| dc.title.translated.spa.fl_str_mv |
Síntesis de materiales compuestos de fosfatos de calcio bifásicos/nanopartículas de oro de elevada cristalinidad, mediante el método de combustión de soluciones, con respuesta antimicrobiana |
| title |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response |
| spellingShingle |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response Fosfatos de Calcio Calcium Phosphates Nanopartículas del Metal Metal Nanoparticles Antiinfecciosos Anti-Infective Agents Ingeniería de Tejidos Tissue Engineering https://id.nlm.nih.gov/mesh/D002130 https://id.nlm.nih.gov/mesh/D053768 https://id.nlm.nih.gov/mesh/D000890 https://id.nlm.nih.gov/mesh/D023822 |
| title_short |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response |
| title_full |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response |
| title_fullStr |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response |
| title_full_unstemmed |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response |
| title_sort |
Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response |
| dc.creator.fl_str_mv |
Robledo Restrepo, Sara María Ospina Aristizábal, Victoria Eugenia Lopera Sepúlveda, Alex Arbey Zutta Villate, Julián Mateo Gómez Zapata, Adrián Puerta Ortiz, Jorge Anselmo Chavarriaga Miranda, Edgar Andrés Bezzon, Vinicius D.N. Paucar Álvarez, Carlos Guillermo García García, Claudia Patricia |
| dc.contributor.author.none.fl_str_mv |
Robledo Restrepo, Sara María Ospina Aristizábal, Victoria Eugenia Lopera Sepúlveda, Alex Arbey Zutta Villate, Julián Mateo Gómez Zapata, Adrián Puerta Ortiz, Jorge Anselmo Chavarriaga Miranda, Edgar Andrés Bezzon, Vinicius D.N. Paucar Álvarez, Carlos Guillermo García García, Claudia Patricia |
| dc.contributor.researchgroup.spa.fl_str_mv |
Programa de Estudio y Control de Enfermedades Tropicales (PECET) |
| dc.subject.decs.none.fl_str_mv |
Fosfatos de Calcio Calcium Phosphates Nanopartículas del Metal Metal Nanoparticles Antiinfecciosos Anti-Infective Agents Ingeniería de Tejidos Tissue Engineering |
| topic |
Fosfatos de Calcio Calcium Phosphates Nanopartículas del Metal Metal Nanoparticles Antiinfecciosos Anti-Infective Agents Ingeniería de Tejidos Tissue Engineering https://id.nlm.nih.gov/mesh/D002130 https://id.nlm.nih.gov/mesh/D053768 https://id.nlm.nih.gov/mesh/D000890 https://id.nlm.nih.gov/mesh/D023822 |
| dc.subject.meshuri.none.fl_str_mv |
https://id.nlm.nih.gov/mesh/D002130 https://id.nlm.nih.gov/mesh/D053768 https://id.nlm.nih.gov/mesh/D000890 https://id.nlm.nih.gov/mesh/D023822 |
| description |
ABSTRACT: Calcium phosphates are biomaterials widely used in bone tissue engineering. In recent years, the alternative of obtaining these materials with antimicrobial properties, has been explored due to the multiple advantages that this would imply in the design of devices or implants that prevent the failure of these associated with bacterial colonization. The goal of the present work was obtaining gold nanoparticles supported on biphasic calcium phosphates (BCPs) with high crystallinity by one-step solution combustion technique, and with antimicrobial response, a fact that can significantly reduce the production cost of these materials. X-ray diffractograms (XRD) showed that prepared powders have high crystallinity owing to high temperatures during the combustion reaction, also Rietveld refinement showed that the inclusion of gold nanoparticles (AuNPs) influenced the phases’ ratio obtained. Furthermore, scanning electron microscopy (SEM) showed agglomeration of particles with morphologies with shape tending to be equigranular, while the presence of AuNPs was corroborated by transmission electron microscopy (TEM). All samples that were obtained in a single step, by solution combustion, showed antimicrobial behavior validated through the inhibition halos, whereas particles subjected to thermal treatment lost their antimicrobial response. |
| publishDate |
2022 |
| dc.date.issued.none.fl_str_mv |
2022 |
| dc.date.accessioned.none.fl_str_mv |
2025-01-21T21:18:59Z |
| dc.date.available.none.fl_str_mv |
2025-01-21T21:18:59Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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publishedVersion |
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0366-3175 |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/44298 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.bsecv.2021.03.007 |
| dc.identifier.eissn.none.fl_str_mv |
2173-0431 |
| identifier_str_mv |
0366-3175 10.1016/j.bsecv.2021.03.007 2173-0431 |
| url |
https://hdl.handle.net/10495/44298 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Bol. Soc. Esp. Cerám. Vidr. |
| dc.relation.citationendpage.spa.fl_str_mv |
497 |
| dc.relation.citationissue.spa.fl_str_mv |
5 |
| dc.relation.citationstartpage.spa.fl_str_mv |
487 |
| dc.relation.citationvolume.spa.fl_str_mv |
61 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Boletín de la Sociedad Española de Cerámica y Vidrio |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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info:eu-repo/semantics/openAccess |
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http://purl.org/coar/access_right/c_abf2 |
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http://creativecommons.org/licenses/by-nc-nd/2.5/co/ https://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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11 pagínas |
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application/pd |
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Elsevier |
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Madrid, España |
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Universidad de Antioquia |
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Robledo Restrepo, Sara MaríaOspina Aristizábal, Victoria EugeniaLopera Sepúlveda, Alex ArbeyZutta Villate, Julián MateoGómez Zapata, AdriánPuerta Ortiz, Jorge AnselmoChavarriaga Miranda, Edgar AndrésBezzon, Vinicius D.N.Paucar Álvarez, Carlos GuillermoGarcía García, Claudia PatriciaPrograma de Estudio y Control de Enfermedades Tropicales (PECET)2025-01-21T21:18:59Z2025-01-21T21:18:59Z20220366-3175https://hdl.handle.net/10495/4429810.1016/j.bsecv.2021.03.0072173-0431ABSTRACT: Calcium phosphates are biomaterials widely used in bone tissue engineering. In recent years, the alternative of obtaining these materials with antimicrobial properties, has been explored due to the multiple advantages that this would imply in the design of devices or implants that prevent the failure of these associated with bacterial colonization. The goal of the present work was obtaining gold nanoparticles supported on biphasic calcium phosphates (BCPs) with high crystallinity by one-step solution combustion technique, and with antimicrobial response, a fact that can significantly reduce the production cost of these materials. X-ray diffractograms (XRD) showed that prepared powders have high crystallinity owing to high temperatures during the combustion reaction, also Rietveld refinement showed that the inclusion of gold nanoparticles (AuNPs) influenced the phases’ ratio obtained. Furthermore, scanning electron microscopy (SEM) showed agglomeration of particles with morphologies with shape tending to be equigranular, while the presence of AuNPs was corroborated by transmission electron microscopy (TEM). All samples that were obtained in a single step, by solution combustion, showed antimicrobial behavior validated through the inhibition halos, whereas particles subjected to thermal treatment lost their antimicrobial response.RESUMEN: Los fosfatos de calcio son biomateriales ampliamente usados en ingeniería de tejido óseo. En los últimos anos, ˜ la alternativa de obtener estos materiales con propiedades antimicrobianas ha sido explorada debido a las múltiples ventajas que presentan en el diseño de dispositivos o implantes que incluyan la prevención de fallas asociadas a la colonización bacteriana. El principal objetivo de esta investigación fue obtener nanopartículas de oro soportadas en fosfatos de calcio bifásicos bien cristalizados en una sola etapa mediante la técnica de combustión de soluciones y con respuesta antimicrobiana, un hecho que puede significar la reducción del coste de producción de estos materiales. Los difractogramas de rayos X evidenciaron que los polvos preparados presentaron una alta cristalinidad debido a las altas temperaturas durante la reacción de combustión. El refinamiento Rietveld mostró que la inclusión de las nanopartículas de oro influenciaron la relación de las fases obtenidas. La microscopia electrónica de barrido mostró la aglomeración de partículas con morfologías tendentes a ser equigranulares. La presencia de nanopartículas de oro fue corroborada mediante microscopia electrónica de transmisión. Todas las muestras que fueron obtenidas en un solo paso mediante la combustión de soluciones mostraron un comportamiento antimicrobiano validado a través de halos de inhibición, mientras que, en las partículas sometidas a tratamiento térmico, este comportamiento estuvo ausente.Colombia. Ministerio de Ciencia, Tecnología e Innovación - MinCienciasCOL001509911 pagínasapplication/pdengElsevierMadrid, Españahttp://creativecommons.org/licenses/by-nc-nd/2.5/co/https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial responseSíntesis de materiales compuestos de fosfatos de calcio bifásicos/nanopartículas de oro de elevada cristalinidad, mediante el método de combustión de soluciones, con respuesta antimicrobianaArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionFosfatos de CalcioCalcium PhosphatesNanopartículas del MetalMetal NanoparticlesAntiinfecciososAnti-Infective AgentsIngeniería de TejidosTissue Engineeringhttps://id.nlm.nih.gov/mesh/D002130https://id.nlm.nih.gov/mesh/D053768https://id.nlm.nih.gov/mesh/D000890https://id.nlm.nih.gov/mesh/D023822Bol. Soc. Esp. Cerám. 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