Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission

ABSTRACT: Chagas disease, Trypanosoma cruzi infection, is an insidious cause of heart failure in Latin America. Early diagnosis and treatment are critical to prevent irreversible myocardial damage that progressively accumulates over decades. Several structural barriers account for the less than 1% o...

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Autores:
Arango Ferreira, Catalina
Gual González, Lídia
Lopera Restrepo, Laura Camila
Cantillo Barraza, Omar
Velásquez Marín, Daniela
Restrepo Bustamante, Natalia
Triana Chávez, Omar
Nolan, Melissa S
Tipo de recurso:
Article of investigation
Fecha de publicación:
2021
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/40521
Acceso en línea:
https://hdl.handle.net/10495/40521
Palabra clave:
Enfermedad de Chagas
Chagas Disease
Niño
Child
Colombia
Trypanosoma cruzi
https://id.nlm.nih.gov/mesh/D014355
https://id.nlm.nih.gov/mesh/D002648
https://id.nlm.nih.gov/mesh/D003105
https://id.nlm.nih.gov/mesh/D014349
Rights
openAccess
License
https://creativecommons.org/licenses/by/4.0/
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dc.title.spa.fl_str_mv Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
title Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
spellingShingle Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
Enfermedad de Chagas
Chagas Disease
Niño
Child
Colombia
Trypanosoma cruzi
https://id.nlm.nih.gov/mesh/D014355
https://id.nlm.nih.gov/mesh/D002648
https://id.nlm.nih.gov/mesh/D003105
https://id.nlm.nih.gov/mesh/D014349
title_short Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
title_full Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
title_fullStr Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
title_full_unstemmed Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
title_sort Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission
dc.creator.fl_str_mv Arango Ferreira, Catalina
Gual González, Lídia
Lopera Restrepo, Laura Camila
Cantillo Barraza, Omar
Velásquez Marín, Daniela
Restrepo Bustamante, Natalia
Triana Chávez, Omar
Nolan, Melissa S
dc.contributor.author.none.fl_str_mv Arango Ferreira, Catalina
Gual González, Lídia
Lopera Restrepo, Laura Camila
Cantillo Barraza, Omar
Velásquez Marín, Daniela
Restrepo Bustamante, Natalia
Triana Chávez, Omar
Nolan, Melissa S
dc.contributor.researchgroup.spa.fl_str_mv Biología y Control de Enfermedades Infecciosas
Grupo de Gastrohepatología
Inmunodeficiencias Primarias
dc.subject.decs.none.fl_str_mv Enfermedad de Chagas
Chagas Disease
Niño
Child
Colombia
Trypanosoma cruzi
topic Enfermedad de Chagas
Chagas Disease
Niño
Child
Colombia
Trypanosoma cruzi
https://id.nlm.nih.gov/mesh/D014355
https://id.nlm.nih.gov/mesh/D002648
https://id.nlm.nih.gov/mesh/D003105
https://id.nlm.nih.gov/mesh/D014349
dc.subject.meshuri.none.fl_str_mv https://id.nlm.nih.gov/mesh/D014355
https://id.nlm.nih.gov/mesh/D002648
https://id.nlm.nih.gov/mesh/D003105
https://id.nlm.nih.gov/mesh/D014349
description ABSTRACT: Chagas disease, Trypanosoma cruzi infection, is an insidious cause of heart failure in Latin America. Early diagnosis and treatment are critical to prevent irreversible myocardial damage that progressively accumulates over decades. Several structural barriers account for the less than 1% of cases in Colombia being treated, including poor physician knowledge, especially considering that some regions are considered non-endemic. The two cases reported here represent an emerging epidemiologic scenario associated with pediatric Chagas disease. Both cases are suspected oral transmitted parasitic infection in a geographic region of Colombia (Andean region of Antioquia) where no previous oral transmission of Chagas disease had been reported. Their clinical histories and course of disease are presented here to increase physician awareness of the epidemiologic risk factors and clinical manifestations associated with pediatric oral Chagas disease in Antioquia department, Colombia.
publishDate 2021
dc.date.issued.none.fl_str_mv 2021
dc.date.accessioned.none.fl_str_mv 2024-07-10T21:03:50Z
dc.date.available.none.fl_str_mv 2024-07-10T21:03:50Z
dc.type.spa.fl_str_mv Reporte de caso
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.identifier.citation.spa.fl_str_mv Gual-Gonzalez L, Arango-Ferreira C, Lopera-Restrepo LC, Cantillo-Barraza O, Marín DV, Bustamante NR, Triana-Chavez O, Nolan MS. Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission. Microorganisms. 2021 Dec 22;10(1):8. doi: 10.3390/microorganisms10010008.
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10495/40521
dc.identifier.doi.none.fl_str_mv 10.3390/microorganisms10010008
dc.identifier.eissn.none.fl_str_mv 2076-2607
identifier_str_mv Gual-Gonzalez L, Arango-Ferreira C, Lopera-Restrepo LC, Cantillo-Barraza O, Marín DV, Bustamante NR, Triana-Chavez O, Nolan MS. Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission. Microorganisms. 2021 Dec 22;10(1):8. doi: 10.3390/microorganisms10010008.
10.3390/microorganisms10010008
2076-2607
url https://hdl.handle.net/10495/40521
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Microorganisms
dc.relation.citationendpage.spa.fl_str_mv 9
dc.relation.citationissue.spa.fl_str_mv 1
dc.relation.citationstartpage.spa.fl_str_mv 1
dc.relation.citationvolume.spa.fl_str_mv 10
dc.relation.ispartofjournal.spa.fl_str_mv Microorganisms
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dc.format.extent.spa.fl_str_mv 9 páginas
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dc.publisher.place.spa.fl_str_mv Basilea, Suiza
institution Universidad de Antioquia
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spelling Arango Ferreira, CatalinaGual González, LídiaLopera Restrepo, Laura CamilaCantillo Barraza, OmarVelásquez Marín, DanielaRestrepo Bustamante, NataliaTriana Chávez, OmarNolan, Melissa SBiología y Control de Enfermedades InfecciosasGrupo de GastrohepatologíaInmunodeficiencias Primarias2024-07-10T21:03:50Z2024-07-10T21:03:50Z2021Gual-Gonzalez L, Arango-Ferreira C, Lopera-Restrepo LC, Cantillo-Barraza O, Marín DV, Bustamante NR, Triana-Chavez O, Nolan MS. Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission. Microorganisms. 2021 Dec 22;10(1):8. doi: 10.3390/microorganisms10010008.https://hdl.handle.net/10495/4052110.3390/microorganisms100100082076-2607ABSTRACT: Chagas disease, Trypanosoma cruzi infection, is an insidious cause of heart failure in Latin America. Early diagnosis and treatment are critical to prevent irreversible myocardial damage that progressively accumulates over decades. Several structural barriers account for the less than 1% of cases in Colombia being treated, including poor physician knowledge, especially considering that some regions are considered non-endemic. The two cases reported here represent an emerging epidemiologic scenario associated with pediatric Chagas disease. Both cases are suspected oral transmitted parasitic infection in a geographic region of Colombia (Andean region of Antioquia) where no previous oral transmission of Chagas disease had been reported. Their clinical histories and course of disease are presented here to increase physician awareness of the epidemiologic risk factors and clinical manifestations associated with pediatric oral Chagas disease in Antioquia department, Colombia.COL0012426COL0007865COL00241599 páginasapplication/pdfengMDPIBasilea, Suizahttps://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral TransmissionReporte de casohttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTCASOhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionEnfermedad de ChagasChagas DiseaseNiñoChildColombiaTrypanosoma cruzihttps://id.nlm.nih.gov/mesh/D014355https://id.nlm.nih.gov/mesh/D002648https://id.nlm.nih.gov/mesh/D003105https://id.nlm.nih.gov/mesh/D014349Microorganisms91110MicroorganismsPublicationORIGINALArangoCatalina_2021_Acute_Pediatric_Chagas.pdfArangoCatalina_2021_Acute_Pediatric_Chagas.pdfArtículo de investigaciónapplication/pdf1660767https://bibliotecadigital.udea.edu.co/bitstreams/336cb58a-5a44-4f64-b892-df1aa69a6842/downloadc99064c681db19d2a98bc9183eea8ad2MD51trueAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927https://bibliotecadigital.udea.edu.co/bitstreams/e59215ff-8913-4cf8-a359-9a1c8a1b3ac5/download1646d1f6b96dbbbc38035efc9239ac9cMD52falseAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/6eb1bf91-4248-4c73-ba47-654295beeb39/download8a4605be74aa9ea9d79846c1fba20a33MD53falseAnonymousREADTEXTArangoCatalina_2021_Acute_Pediatric_Chagas.pdf.txtArangoCatalina_2021_Acute_Pediatric_Chagas.pdf.txtExtracted texttext/plain37522https://bibliotecadigital.udea.edu.co/bitstreams/d7e33ce8-ed78-45d0-ab7f-0a095e9c50db/download4cbeecd28267d8fc2068d9c7e65da19bMD56falseAnonymousREADTHUMBNAILArangoCatalina_2021_Acute_Pediatric_Chagas.pdf.jpgArangoCatalina_2021_Acute_Pediatric_Chagas.pdf.jpgGenerated Thumbnailimage/jpeg15494https://bibliotecadigital.udea.edu.co/bitstreams/b31976bb-50a1-48e3-abfd-d4876026e3e9/downloadc058b11831536f229657dd5ec1fb6b93MD57falseAnonymousREAD10495/40521oai:bibliotecadigital.udea.edu.co:10495/405212025-03-26 18:10:56.851https://creativecommons.org/licenses/by/4.0/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.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