Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in fl avivirus-naive healthy adults in Colombia: a randomised, placebo-controlled, phase 1 study

ABSTRACT: Background Dengue virus is the most serious mosquito-borne viral threat to public health and no vaccines or antiviral therapies are approved for dengue fever. The tetravalent DENVax vaccine contains a molecularly characterised live attenuated dengue serotype-2 virus (DENVax-2) and three re...

Full description

Autores:

Osorio Benitez, Jorge Emilio
Vélez Bernal, Iván Darío
Thomson, Cynthia
López Carvajal, Liliana
Jiménez Echavarría, Alejandra María
Haller, Aurelia A.
Silengo, Shawn
Scott, Jaclyn
Boroughs, Karen L.
Stovall, Janae L.
Luy, Betty E.
Arguello, John
Beatty, Mark E.
Santangelo, Joseph
Gordon, Gilad S.
Huang, Claire Y-H
Stinchcomb, Dan T.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2014

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43302

Acceso en línea:

https://hdl.handle.net/10495/43302

Palabra clave:

Anticuerpos Antivirales
Antibodies, Viral
Vacunas contra el Dengue
Dengue Vaccines
Virus del Dengue
Dengue Virus
Método Doble Ciego
Double-Blind Method
Vacunación
Vaccination
Vacunas Atenuadas
Vaccines, Attenuated
Vacunas Sintéticas
Vaccines, Synthetic
https://id.nlm.nih.gov/mesh/D000914
https://id.nlm.nih.gov/mesh/D053059
https://id.nlm.nih.gov/mesh/D003716
https://id.nlm.nih.gov/mesh/D004311
https://id.nlm.nih.gov/mesh/D014611
https://id.nlm.nih.gov/mesh/D014613
https://id.nlm.nih.gov/mesh/D014614

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/