A new host-targeted antiviral cyclolignan (SAU-22.107) for Dengue Virus infection in cell cultures. Potential action mechanisms based on cell imaging

ABSTRACT: Dengue virus (DENV) infection is the most arbovirosis in the world. However, medications have not been approved for its treatment. Drug discovery based on the host-targeted antiviral (HTA) constitutes a new promising strategy, considering their high genetic barrier to resistance and the lo...

Full description

Autores:

Miranda Brand, Yaneth
Roa Linares, Vicky Constanza
Santiago Dugarte, Carolina
Del Olmo, Esther
López Pérez, José Luis
Betancur Galvis, Liliana Amparo
Gallego Gómez, Juan Carlos
San Feliciano, Arturo

Tipo de recurso:

Article of investigation

Fecha de publicación:

2023

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43349

Acceso en línea:

https://hdl.handle.net/10495/43349

Palabra clave:

Antivirales
Antiviral Agents
Técnicas de Cultivo de Célula
Cell Culture Techniques
Virus del Dengue
Dengue Virus
Virosis
Virus Diseases
Replicación Viral
Virus Replication
https://id.nlm.nih.gov/mesh/D000998
https://id.nlm.nih.gov/mesh/D018929
https://id.nlm.nih.gov/mesh/D003716
https://id.nlm.nih.gov/mesh/D014777
https://id.nlm.nih.gov/mesh/D014779

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/