Differential protein expression in seminal plasma from fertile and infertile males
ABSTARCT: The aim of this study was to analyze human seminal plasma proteins in association with male fertility status using the proteomic mass spectrometry technology Surface-Enhanced Laser Desorption Ionization Time-of-Flight (SELDI-TOF-MS). MATERIALS AND METHODS: Semen analysis was performed usin...
- Autores:
-
Cadavid Jaramillo, Ángela Patricia
Álvarez Gómez, Ángela María
Markert, Udor
Cardona Maya, Walter Darío
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2014
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/10915
- Acceso en línea:
- http://hdl.handle.net/10495/10915
- Palabra clave:
- Fertility
Proteomics
Seminal plasma
Ionization time-of-flight
Enhanced laser desorption
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-sa/2.5/co/
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| dc.title.spa.fl_str_mv |
Differential protein expression in seminal plasma from fertile and infertile males |
| title |
Differential protein expression in seminal plasma from fertile and infertile males |
| spellingShingle |
Differential protein expression in seminal plasma from fertile and infertile males Fertility Proteomics Seminal plasma Ionization time-of-flight Enhanced laser desorption |
| title_short |
Differential protein expression in seminal plasma from fertile and infertile males |
| title_full |
Differential protein expression in seminal plasma from fertile and infertile males |
| title_fullStr |
Differential protein expression in seminal plasma from fertile and infertile males |
| title_full_unstemmed |
Differential protein expression in seminal plasma from fertile and infertile males |
| title_sort |
Differential protein expression in seminal plasma from fertile and infertile males |
| dc.creator.fl_str_mv |
Cadavid Jaramillo, Ángela Patricia Álvarez Gómez, Ángela María Markert, Udor Cardona Maya, Walter Darío |
| dc.contributor.author.none.fl_str_mv |
Cadavid Jaramillo, Ángela Patricia Álvarez Gómez, Ángela María Markert, Udor Cardona Maya, Walter Darío |
| dc.contributor.researchgroup.spa.fl_str_mv |
Grupo Reproducción |
| dc.subject.none.fl_str_mv |
Fertility Proteomics Seminal plasma Ionization time-of-flight Enhanced laser desorption |
| topic |
Fertility Proteomics Seminal plasma Ionization time-of-flight Enhanced laser desorption |
| description |
ABSTARCT: The aim of this study was to analyze human seminal plasma proteins in association with male fertility status using the proteomic mass spectrometry technology Surface-Enhanced Laser Desorption Ionization Time-of-Flight (SELDI-TOF-MS). MATERIALS AND METHODS: Semen analysis was performed using conventional methods. Protein profiles of the seminal plasma were obtained by SELDI-TOF mass spectrometry over a strong anion exchanger, ProteinChip(®) Q10 array. RESULTS AND CONCLUSION: We found statistically significant differences in motility and sperm count between fertile and infertile men. In addition, we observed ten seminal proteins that are significantly up-regulated in the infertile group. In conclusion, comparison of seminal plasma proteome in fertile and infertile men provides new aspects in the physiology of male fertility and might help in identifying novel markers of male infertility. |
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2014 |
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2014 |
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2019-04-09T21:00:26Z |
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2019-04-09T21:00:26Z |
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Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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Cadavid J AP, Alvarez A, Markert UR, Cardona Maya W. Differential protein expression in seminal plasma from fertile and infertile males. J Hum Reprod Sci. 2014 Jul;7(3):206-11 |
| dc.identifier.issn.none.fl_str_mv |
0974-1208 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/10915 |
| dc.identifier.doi.none.fl_str_mv |
10.4103/0974-1208.142485 |
| dc.identifier.eissn.none.fl_str_mv |
1998-4766 |
| identifier_str_mv |
Cadavid J AP, Alvarez A, Markert UR, Cardona Maya W. Differential protein expression in seminal plasma from fertile and infertile males. J Hum Reprod Sci. 2014 Jul;7(3):206-11 0974-1208 10.4103/0974-1208.142485 1998-4766 |
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http://hdl.handle.net/10495/10915 |
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eng |
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eng |
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J Hum Reprod Sci |
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211 |
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3 |
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206 |
| dc.relation.citationvolume.spa.fl_str_mv |
7 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Journal of Human Reproductive Sciences |
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http://creativecommons.org/licenses/by-nc-sa/2.5/co/ |
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https://creativecommons.org/licenses/by-nc-sa/4.0/ |
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Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO) |
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Medknow Publications |
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India |
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Universidad de Antioquia |
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Cadavid Jaramillo, Ángela PatriciaÁlvarez Gómez, Ángela MaríaMarkert, UdorCardona Maya, Walter DaríoGrupo Reproducción2019-04-09T21:00:26Z2019-04-09T21:00:26Z2014Cadavid J AP, Alvarez A, Markert UR, Cardona Maya W. Differential protein expression in seminal plasma from fertile and infertile males. J Hum Reprod Sci. 2014 Jul;7(3):206-110974-1208http://hdl.handle.net/10495/1091510.4103/0974-1208.1424851998-4766ABSTARCT: The aim of this study was to analyze human seminal plasma proteins in association with male fertility status using the proteomic mass spectrometry technology Surface-Enhanced Laser Desorption Ionization Time-of-Flight (SELDI-TOF-MS). MATERIALS AND METHODS: Semen analysis was performed using conventional methods. Protein profiles of the seminal plasma were obtained by SELDI-TOF mass spectrometry over a strong anion exchanger, ProteinChip(®) Q10 array. RESULTS AND CONCLUSION: We found statistically significant differences in motility and sperm count between fertile and infertile men. In addition, we observed ten seminal proteins that are significantly up-regulated in the infertile group. In conclusion, comparison of seminal plasma proteome in fertile and infertile men provides new aspects in the physiology of male fertility and might help in identifying novel markers of male infertility.5application/pdfengMedknow PublicationsIndiahttp://creativecommons.org/licenses/by-nc-sa/2.5/co/https://creativecommons.org/licenses/by-nc-sa/4.0/Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2FertilityProteomicsSeminal plasmaIonization time-of-flightEnhanced laser desorptionDifferential protein expression in seminal plasma from fertile and infertile malesArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionJ Hum Reprod Sci21132067Journal of Human Reproductive SciencesPublicationORIGINALCadavidPatricia_2014_DifferentialProteinPlasma.pdfCadavidPatricia_2014_DifferentialProteinPlasma.pdfArtículo de investigaciónapplication/pdf876108https://bibliotecadigital.udea.edu.co/bitstreams/c3f17aec-cfa9-406a-9545-a9175a84a294/downloadd42d8ad412444fed8ff670548c1cf9acMD51trueAnonymousREADCC-LICENSElicense_urllicense_urltext/plain; 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