Genetic inferences about paternity in the Paisa community from Antioquia, Colombia

ABSTRACT: This paper compiles gene frequencies of classical, and DNA genetic markers in order to solve the power of non exclusion paternity for the Antioquian community in Colombia. Two ways of quantifying the rarity of non-exclusion of paternity were used. The first way was the Bayesian approach th...

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Autores:
Bravo Aguiar, María Luisa Judith
Arcos Burgos, Oscar Mauricio
Tipo de recurso:
Article of investigation
Fecha de publicación:
1999
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/20927
Acceso en línea:
http://hdl.handle.net/10495/20927
https://revistas.udea.edu.co/index.php/actbio/article/view/329743
Palabra clave:
Marcadores Genéticos
Genetic Markers
Genética
Genetics
Genética de Población
Genetics Population
Antioquia (Colombia)
Pruebas de paternidad
Paternity tests
Grupos sanguíneos
Blood groups
Colombia
http://aims.fao.org/aos/agrovoc/c_13136
http://aims.fao.org/aos/agrovoc/c_965
http://aims.fao.org/aos/agrovoc/c_1767
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-sa/4.0/
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dc.title.spa.fl_str_mv Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
dc.title.translated.spa.fl_str_mv Inferencias genéticas sobre asignación de paternidad en la comunidad paisa de Antioquia, Colombia
title Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
spellingShingle Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
Marcadores Genéticos
Genetic Markers
Genética
Genetics
Genética de Población
Genetics Population
Antioquia (Colombia)
Pruebas de paternidad
Paternity tests
Grupos sanguíneos
Blood groups
Colombia
http://aims.fao.org/aos/agrovoc/c_13136
http://aims.fao.org/aos/agrovoc/c_965
http://aims.fao.org/aos/agrovoc/c_1767
title_short Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
title_full Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
title_fullStr Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
title_full_unstemmed Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
title_sort Genetic inferences about paternity in the Paisa community from Antioquia, Colombia
dc.creator.fl_str_mv Bravo Aguiar, María Luisa Judith
Arcos Burgos, Oscar Mauricio
dc.contributor.author.none.fl_str_mv Bravo Aguiar, María Luisa Judith
Arcos Burgos, Oscar Mauricio
dc.contributor.researchgroup.spa.fl_str_mv Genética Regeneración y Cáncer
dc.subject.decs.none.fl_str_mv Marcadores Genéticos
Genetic Markers
Genética
Genetics
Genética de Población
Genetics Population
Antioquia (Colombia)
topic Marcadores Genéticos
Genetic Markers
Genética
Genetics
Genética de Población
Genetics Population
Antioquia (Colombia)
Pruebas de paternidad
Paternity tests
Grupos sanguíneos
Blood groups
Colombia
http://aims.fao.org/aos/agrovoc/c_13136
http://aims.fao.org/aos/agrovoc/c_965
http://aims.fao.org/aos/agrovoc/c_1767
dc.subject.agrovoc.none.fl_str_mv Pruebas de paternidad
Paternity tests
Grupos sanguíneos
Blood groups
Colombia
dc.subject.agrovocuri.none.fl_str_mv http://aims.fao.org/aos/agrovoc/c_13136
http://aims.fao.org/aos/agrovoc/c_965
http://aims.fao.org/aos/agrovoc/c_1767
description ABSTRACT: This paper compiles gene frequencies of classical, and DNA genetic markers in order to solve the power of non exclusion paternity for the Antioquian community in Colombia. Two ways of quantifying the rarity of non-exclusion of paternity were used. The first way was the Bayesian approach that compute a likelihood ratio of the trio with the putative father as real father versus the trio with the real father as a random male. This likelihood ratio or paternity index can be transformed into a posterior probability if a prior probability of paternity is supplied. The other approach was that of the computation of the probability that a random male would not be excluded by at least one of the tests given the phenotypes of the mother and child. In this case, we carried out the estimation of the paternity index and of the non exclusion probability. Both of these measures are computed for each locus separately and cumulated over all loci. All analyses are exemplified by using a real example. Finally, we estimated the paternity exclusion probability by using the Ohno et al. equation for each locus with alleles.
publishDate 1999
dc.date.issued.none.fl_str_mv 1999
dc.date.accessioned.none.fl_str_mv 2021-07-16T20:28:53Z
dc.date.available.none.fl_str_mv 2021-07-16T20:28:53Z
dc.type.spa.fl_str_mv Artículo de investigación
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.identifier.citation.spa.fl_str_mv Bravo, M., & Arcos, M. (1999). Genetic inferences about paternity in the Paisa community from Antioquia, Colombia. Actualidades Biológicas, 21(71), 143-149. https://revistas.udea.edu.co/index.php/actbio/article/view/329743
dc.identifier.issn.none.fl_str_mv 0304-3584
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/20927
dc.identifier.eissn.none.fl_str_mv 2145-7166
dc.identifier.url.spa.fl_str_mv https://revistas.udea.edu.co/index.php/actbio/article/view/329743
identifier_str_mv Bravo, M., & Arcos, M. (1999). Genetic inferences about paternity in the Paisa community from Antioquia, Colombia. Actualidades Biológicas, 21(71), 143-149. https://revistas.udea.edu.co/index.php/actbio/article/view/329743
0304-3584
2145-7166
url http://hdl.handle.net/10495/20927
https://revistas.udea.edu.co/index.php/actbio/article/view/329743
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Actual. Biol.
dc.relation.citationendpage.spa.fl_str_mv 149
dc.relation.citationissue.spa.fl_str_mv 71
dc.relation.citationstartpage.spa.fl_str_mv 143
dc.relation.citationvolume.spa.fl_str_mv 21
dc.relation.ispartofjournal.spa.fl_str_mv Actualidades Biológicas
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dc.publisher.spa.fl_str_mv Universidad de Antioquia, Facultad de Ciencias Exactas y Naturales, Instituto de Biología
dc.publisher.place.spa.fl_str_mv Medellín, Colombia
institution Universidad de Antioquia
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spelling Bravo Aguiar, María Luisa JudithArcos Burgos, Oscar MauricioGenética Regeneración y Cáncer2021-07-16T20:28:53Z2021-07-16T20:28:53Z1999Bravo, M., & Arcos, M. (1999). Genetic inferences about paternity in the Paisa community from Antioquia, Colombia. Actualidades Biológicas, 21(71), 143-149. https://revistas.udea.edu.co/index.php/actbio/article/view/3297430304-3584http://hdl.handle.net/10495/209272145-7166https://revistas.udea.edu.co/index.php/actbio/article/view/329743ABSTRACT: This paper compiles gene frequencies of classical, and DNA genetic markers in order to solve the power of non exclusion paternity for the Antioquian community in Colombia. Two ways of quantifying the rarity of non-exclusion of paternity were used. The first way was the Bayesian approach that compute a likelihood ratio of the trio with the putative father as real father versus the trio with the real father as a random male. This likelihood ratio or paternity index can be transformed into a posterior probability if a prior probability of paternity is supplied. The other approach was that of the computation of the probability that a random male would not be excluded by at least one of the tests given the phenotypes of the mother and child. In this case, we carried out the estimation of the paternity index and of the non exclusion probability. Both of these measures are computed for each locus separately and cumulated over all loci. All analyses are exemplified by using a real example. Finally, we estimated the paternity exclusion probability by using the Ohno et al. equation for each locus with alleles.RESUMEN: Este artículo compila información sobre la distribución de las frecuencias genéticas de marcadores genéticos clásicos y de DNA con la finalidad de observar el comportamiento del parámetro de no-exclusión en disputas de paternidad originadas en individuos que pertenecen al departamento de Antioquia, Colombia. Primero usamos la aproximación Bayesiana, que computa la probabilidad del trío en problema tomando al padre real como el padre putativo, comparada contra la probabilidad de un trío con un padre aleatorio tomado de la población problema. Esta razón de verosimilitud o índice de paternidad puede ser transformada en una probabilidad posterior si una probabilidad a priori de paternidad es entregada. La otra aproximación que usamos fue el cómputo de la probabilidad de que un hombre aleatorio no sea excluido por al menos una de las pruebas biológicas realizadas teniendo como condición los fenotipos de la madre y el niño. En este caso, estimamos el índice de paternidad y la probabilidad de no-exclusión. Todos los parámetros fueron estimados para cada locus y acumulados sobre todos los loci. Se usó un ejemplo real como aproximación práctica. Finalmente estimamos el poder de exclusión de la paternidad de acuerdo con la ecuación de Ohno et al. para cada locus con n alelos.COL00067697application/pdfengUniversidad de Antioquia, Facultad de Ciencias Exactas y Naturales, Instituto de BiologíaMedellín, Colombiahttps://creativecommons.org/licenses/by-nc-sa/4.0/http://creativecommons.org/licenses/by-nc-sa/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Genetic inferences about paternity in the Paisa community from Antioquia, ColombiaInferencias genéticas sobre asignación de paternidad en la comunidad paisa de Antioquia, ColombiaArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionMarcadores GenéticosGenetic MarkersGenéticaGeneticsGenética de PoblaciónGenetics PopulationAntioquia (Colombia)Pruebas de paternidadPaternity testsGrupos sanguíneosBlood groupsColombiahttp://aims.fao.org/aos/agrovoc/c_13136http://aims.fao.org/aos/agrovoc/c_965http://aims.fao.org/aos/agrovoc/c_1767Actual. 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