Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma

ABSTRACT: Endocrinologically active pituitary adenomas are treated either with surgery, radiotherapy or various drugs, including dopamine agonists, long-acting somatostatin analogs, growth hormone receptor antagonists, or corticosteroid secretion inhibitors. Fully 35% to 55% of pituitary adenomas in...

Full description

Autores:
Ortiz Gómez, León Darío
Syro Moreno, Luis Vicente
Ersen, Ayca
Penagos, Luis C.
Uribe, Humberto
Scheithauer, Bernd W.
Rotondo, Fabio
Horvath, Eva
Kovacs, Kalman
Tipo de recurso:
Article of investigation
Fecha de publicación:
2014
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/39509
Acceso en línea:
https://hdl.handle.net/10495/39509
Palabra clave:
Temozolomida
Temozolomide
Adenoma
Adenoma - cirugía
Adenoma - tratamiento farmacológico
Adenoma - radioterapia
https://id.nlm.nih.gov/mesh/D000077204
https://id.nlm.nih.gov/mesh/D000236
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/39509
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network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
title Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
spellingShingle Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
Temozolomida
Temozolomide
Adenoma
Adenoma - cirugía
Adenoma - tratamiento farmacológico
Adenoma - radioterapia
https://id.nlm.nih.gov/mesh/D000077204
https://id.nlm.nih.gov/mesh/D000236
title_short Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
title_full Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
title_fullStr Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
title_full_unstemmed Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
title_sort Non-uniform Response to Temozolomide Therapy in a Pituitary Gonadotroph Adenoma
dc.creator.fl_str_mv Ortiz Gómez, León Darío
Syro Moreno, Luis Vicente
Ersen, Ayca
Penagos, Luis C.
Uribe, Humberto
Scheithauer, Bernd W.
Rotondo, Fabio
Horvath, Eva
Kovacs, Kalman
dc.contributor.author.none.fl_str_mv Ortiz Gómez, León Darío
Syro Moreno, Luis Vicente
Ersen, Ayca
Penagos, Luis C.
Uribe, Humberto
Scheithauer, Bernd W.
Rotondo, Fabio
Horvath, Eva
Kovacs, Kalman
dc.contributor.researchgroup.spa.fl_str_mv Genética, Regeneración y Cáncer
dc.subject.decs.none.fl_str_mv Temozolomida
Temozolomide
Adenoma
Adenoma - cirugía
Adenoma - tratamiento farmacológico
Adenoma - radioterapia
topic Temozolomida
Temozolomide
Adenoma
Adenoma - cirugía
Adenoma - tratamiento farmacológico
Adenoma - radioterapia
https://id.nlm.nih.gov/mesh/D000077204
https://id.nlm.nih.gov/mesh/D000236
dc.subject.meshuri.none.fl_str_mv https://id.nlm.nih.gov/mesh/D000077204
https://id.nlm.nih.gov/mesh/D000236
description ABSTRACT: Endocrinologically active pituitary adenomas are treated either with surgery, radiotherapy or various drugs, including dopamine agonists, long-acting somatostatin analogs, growth hormone receptor antagonists, or corticosteroid secretion inhibitors. Fully 35% to 55% of pituitary adenomas invade adjacent structures. This figure is lower in gonadotroph adenomas, less than 5% compared to other adenoma types. Clinical management of invasive adenomas is challenging, and most of them tend to recur after surgery.
publishDate 2014
dc.date.issued.none.fl_str_mv 2014
dc.date.accessioned.none.fl_str_mv 2024-05-31T22:41:01Z
dc.date.available.none.fl_str_mv 2024-05-31T22:41:01Z
dc.type.spa.fl_str_mv Reporte de caso
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.redcol.spa.fl_str_mv https://purl.org/redcol/resource_type/ARTCASO
dc.type.coarversion.spa.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
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dc.identifier.issn.none.fl_str_mv 0317-1671
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10495/39509
dc.identifier.doi.none.fl_str_mv 10.1017/s0317167100018242
dc.identifier.eissn.none.fl_str_mv 2057-0155
identifier_str_mv 0317-1671
10.1017/s0317167100018242
2057-0155
url https://hdl.handle.net/10495/39509
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Can. J. Neurol. Sci.
dc.relation.citationendpage.spa.fl_str_mv 685
dc.relation.citationissue.spa.fl_str_mv 5
dc.relation.citationstartpage.spa.fl_str_mv 683
dc.relation.citationvolume.spa.fl_str_mv 39
dc.relation.ispartofjournal.spa.fl_str_mv Canadian Journal of Neurological Sciences
dc.rights.uri.spa.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.format.extent.spa.fl_str_mv 3 páginas
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dc.publisher.spa.fl_str_mv Cambridge University Press
dc.publisher.place.spa.fl_str_mv Cambridge, Inglaterra
institution Universidad de Antioquia
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spelling Ortiz Gómez, León DaríoSyro Moreno, Luis VicenteErsen, AycaPenagos, Luis C.Uribe, HumbertoScheithauer, Bernd W.Rotondo, FabioHorvath, EvaKovacs, KalmanGenética, Regeneración y Cáncer2024-05-31T22:41:01Z2024-05-31T22:41:01Z20140317-1671https://hdl.handle.net/10495/3950910.1017/s03171671000182422057-0155ABSTRACT: Endocrinologically active pituitary adenomas are treated either with surgery, radiotherapy or various drugs, including dopamine agonists, long-acting somatostatin analogs, growth hormone receptor antagonists, or corticosteroid secretion inhibitors. Fully 35% to 55% of pituitary adenomas invade adjacent structures. This figure is lower in gonadotroph adenomas, less than 5% compared to other adenoma types. 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