The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy
ABSTRACT: Astrocytes are commonly involved in negative responses through their hyperreactivity and glial scar formation in excitotoxic and/or mechanical injuries. But, astrocytes are also specialized glial cells of the nervous system that perform multiple homeostatic functions for the survival and m...
- Autores:
-
Becerra Calixto, Andrea del Pilar
Cardona Gómez, Gloria Patricia
- Tipo de recurso:
- Review article
- Fecha de publicación:
- 2017
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/23069
- Acceso en línea:
- http://hdl.handle.net/10495/23069
https://www.frontiersin.org/articles/10.3389/fnmol.2017.00088/full
- Palabra clave:
- Astrocitos
Astrocytes
Tratamiento Basado en Trasplante de Células y Tejidos
Cell- and Tissue-Based Therapy
Neuroprotección
Neuroprotection
Isquemia Encefálica
Brain Ischemia
Excitotoxicidad
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
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The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy |
| title |
The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy |
| spellingShingle |
The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy Astrocitos Astrocytes Tratamiento Basado en Trasplante de Células y Tejidos Cell- and Tissue-Based Therapy Neuroprotección Neuroprotection Isquemia Encefálica Brain Ischemia Excitotoxicidad |
| title_short |
The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy |
| title_full |
The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy |
| title_fullStr |
The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy |
| title_full_unstemmed |
The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy |
| title_sort |
The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell Therapy |
| dc.creator.fl_str_mv |
Becerra Calixto, Andrea del Pilar Cardona Gómez, Gloria Patricia |
| dc.contributor.author.none.fl_str_mv |
Becerra Calixto, Andrea del Pilar Cardona Gómez, Gloria Patricia |
| dc.contributor.researchgroup.spa.fl_str_mv |
Grupo de Neurociencias de Antioquia |
| dc.subject.decs.none.fl_str_mv |
Astrocitos Astrocytes Tratamiento Basado en Trasplante de Células y Tejidos Cell- and Tissue-Based Therapy Neuroprotección Neuroprotection Isquemia Encefálica Brain Ischemia |
| topic |
Astrocitos Astrocytes Tratamiento Basado en Trasplante de Células y Tejidos Cell- and Tissue-Based Therapy Neuroprotección Neuroprotection Isquemia Encefálica Brain Ischemia Excitotoxicidad |
| dc.subject.proposal.spa.fl_str_mv |
Excitotoxicidad |
| description |
ABSTRACT: Astrocytes are commonly involved in negative responses through their hyperreactivity and glial scar formation in excitotoxic and/or mechanical injuries. But, astrocytes are also specialized glial cells of the nervous system that perform multiple homeostatic functions for the survival and maintenance of the neurovascular unit. Astrocytes have neuroprotective, angiogenic, immunomodulatory, neurogenic, and antioxidant properties and modulate synaptic function. This makes them excellent candidates as a source of neuroprotection and neurorestoration in tissues affected by ischemia/reperfusion, when some of their deregulated genes can be controlled. Therefore, this review analyzes pro-survival responses of astrocytes that would allow their use in cell therapy strategies. |
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2017 |
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2017 |
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2021-10-09T20:48:33Z |
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2021-10-09T20:48:33Z |
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Artículo de revisión |
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10.3389/fnmol.2017.00088 |
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1662-5099 |
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https://www.frontiersin.org/articles/10.3389/fnmol.2017.00088/full |
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10.3389/fnmol.2017.00088 1662-5099 |
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eng |
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eng |
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Front. Mol. Neurosci. |
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12 |
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1 |
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Frontiers in Molecular Neuroscience |
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Becerra Calixto, Andrea del PilarCardona Gómez, Gloria PatriciaGrupo de Neurociencias de Antioquia2021-10-09T20:48:33Z2021-10-09T20:48:33Z2017http://hdl.handle.net/10495/2306910.3389/fnmol.2017.000881662-5099https://www.frontiersin.org/articles/10.3389/fnmol.2017.00088/fullABSTRACT: Astrocytes are commonly involved in negative responses through their hyperreactivity and glial scar formation in excitotoxic and/or mechanical injuries. But, astrocytes are also specialized glial cells of the nervous system that perform multiple homeostatic functions for the survival and maintenance of the neurovascular unit. Astrocytes have neuroprotective, angiogenic, immunomodulatory, neurogenic, and antioxidant properties and modulate synaptic function. This makes them excellent candidates as a source of neuroprotection and neurorestoration in tissues affected by ischemia/reperfusion, when some of their deregulated genes can be controlled. Therefore, this review analyzes pro-survival responses of astrocytes that would allow their use in cell therapy strategies.COL001074412application/pdfengFrontiers Research FoundationLausana, Suizahttp://creativecommons.org/licenses/by/2.5/co/https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2The Role of Astrocytes in Neuroprotection after Brain Stroke : Potential in Cell TherapyArtículo de revisiónhttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAstrocitosAstrocytesTratamiento Basado en Trasplante de Células y TejidosCell- and Tissue-Based TherapyNeuroprotecciónNeuroprotectionIsquemia EncefálicaBrain IschemiaExcitotoxicidadFront. Mol. 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