In vitro and in silico analysis of Galanthine from Zephyranthes carinata as an inhibitor of acetylcholinesterase

ABSTRACT: Zephyranthes carinata Herb., a specie of the Amaryllidoideae subfamily, has been reported to have inhibitory activity against acetylcholinesterase. However, scientific evidence related to their bioactive alkaloids has been lacking. Thus, this study describes the isolation of the alkaloids...

Full description

Autores:

Osorio Durango, Edison
Sierra Henao, Karina Andrea
Bastida Armengol, Jaume
Cortes Rendón, Natalie Charlotte
de Andrade, Jean Paulo
Tallini, Luciana R.
Osorio, Edison H.
Yañéz, Osvaldo
Osorio, Manuel Isaías
Oleas, Nora H.
García Beltrán, Olimpo
de S. Borges, Warley

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39189

Acceso en línea:

https://hdl.handle.net/10495/39189

Palabra clave:

Acetilcolinesterasa - metabolismo
Acetylcholinesterase - metabolism
Alcaloides - farmacología
Alkaloids - pharmacology
Amaryllidaceae - química
Amaryllidaceae - chemistry
Amaryllidaceae - metabolismo
Amaryllidaceae - metabolism
Butirilcolinesterasa - metabolismo
Butyrylcholinesterase - metabolism
Inhibidores de la Colinesterasa - química
Cholinesterase Inhibitors - chemistry
Inhibidores de la Colinesterasa - farmacología
Cholinesterase Inhibitors - pharmacology
Simulación del Acoplamiento Molecular
Molecular Docking Simulation
https://id.nlm.nih.gov/mesh/D000110
https://id.nlm.nih.gov/mesh/D000470
https://id.nlm.nih.gov/mesh/D000070378
https://id.nlm.nih.gov/mesh/D002091
https://id.nlm.nih.gov/mesh/D002800
https://id.nlm.nih.gov/mesh/D062105

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/