Clinical Manifestations and Outcomes of Respiratory Syncytial Virus Infection in Children Less Than Two Years in Colombia

ABSTRACT: This retrospective study describes the epidemiology and identifies risk factors associated with severe complications in lower respiratory tract infection (LRTI) due to respiratory syncytial virus (RSV) in a population of infants hospitalized in a tertiary care hospital in a tropical region of Colombia. A severe complication in RSV LRTI was defined as the presence of SpO2 ≤ 90% in the emergency room and/or pneumonia and/or atelectasis and/or sepsis and/or respiratory failure during hospitalization. RSV was detected in 193 (46.3%) of 417 patients with LRTI. The average hospital stay lasted for 5.9 days. Severe hypoxemia (SpO2≤ 90% in the emergency department) was resent in 57.5% of the patients. After controlling for potential confounders, comorbidities bronchopulmonary dysplasia, congenital heart disease, length of hospital stay, and alveolar infiltrates in X-ray were independent predictors of severe complications in RSV LRTI.

• Autores: Buendía Rodríguez, Jefferson Antonio; Guerrero Patiño, Diana; Polack, Fernando P.
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2021
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/44841
• Acceso en línea: https://hdl.handle.net/10495/44841
• Palabra clave: Saturación de Oxígeno; Oxygen Saturation; Virus Sincitial Respiratorio Humano; Respiratory Syncytial Virus, Human; Estudios Retrospectivos; Retrospective Studies; Factores de Riesgo; Risk Factors; Colombia - epidemiología; Colombia - epidemiology; Niño; Child; Enfermedades Respiratorias; Respiratory Tract Diseases; https://id.nlm.nih.gov/mesh/D000089382; https://id.nlm.nih.gov/mesh/D018113; https://id.nlm.nih.gov/mesh/D012189; https://id.nlm.nih.gov/mesh/D012307; https://id.nlm.nih.gov/mesh/D003105; https://id.nlm.nih.gov/mesh/D002648; https://id.nlm.nih.gov/mesh/D012140
• Rights: openAccess
• License: http://creativecommons.org/licenses/by/2.5/co/