Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings
ABSTRACT: Numerous surgical and nonsurgical modalities are available to treat basal cell carcinoma (BCC), but their true effectiveness and safety is unknown. This article summarizes the evidence presented in a recent Cochrane review and aims to facilitate the interpretation of the review's find...
- Autores:
-
Aguirre Acevedo, Daniel Camilo
Sanclemente Mesa, Gloria
Thomson, Jason
- Tipo de recurso:
- Review article
- Fecha de publicación:
- 2023
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/43352
- Acceso en línea:
- https://hdl.handle.net/10495/43352
- Palabra clave:
- Carcinoma Basocelular
Carcinoma, Basal Cell
Dolor
Pain
Reproducibilidad de los Resultados
Reproducibility of Results
Neoplasias Cutáneas
Skin Neoplasms
https://id.nlm.nih.gov/mesh/D002280
https://id.nlm.nih.gov/mesh/D010146
https://id.nlm.nih.gov/mesh/D015203
https://id.nlm.nih.gov/mesh/D012878
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/
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Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings |
| dc.title.translated.spa.fl_str_mv |
Intervenciones para el carcinoma basocelular cutáneo (revisión Cochrane): Resumen de las principales comparaciones e interpretación práctica de los resultados |
| title |
Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings |
| spellingShingle |
Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings Carcinoma Basocelular Carcinoma, Basal Cell Dolor Pain Reproducibilidad de los Resultados Reproducibility of Results Neoplasias Cutáneas Skin Neoplasms https://id.nlm.nih.gov/mesh/D002280 https://id.nlm.nih.gov/mesh/D010146 https://id.nlm.nih.gov/mesh/D015203 https://id.nlm.nih.gov/mesh/D012878 |
| title_short |
Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings |
| title_full |
Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings |
| title_fullStr |
Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings |
| title_full_unstemmed |
Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings |
| title_sort |
Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings |
| dc.creator.fl_str_mv |
Aguirre Acevedo, Daniel Camilo Sanclemente Mesa, Gloria Thomson, Jason |
| dc.contributor.author.none.fl_str_mv |
Aguirre Acevedo, Daniel Camilo Sanclemente Mesa, Gloria Thomson, Jason |
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GRID - Grupo de Investigación Dermatológica |
| dc.subject.decs.none.fl_str_mv |
Carcinoma Basocelular Carcinoma, Basal Cell Dolor Pain Reproducibilidad de los Resultados Reproducibility of Results Neoplasias Cutáneas Skin Neoplasms |
| topic |
Carcinoma Basocelular Carcinoma, Basal Cell Dolor Pain Reproducibilidad de los Resultados Reproducibility of Results Neoplasias Cutáneas Skin Neoplasms https://id.nlm.nih.gov/mesh/D002280 https://id.nlm.nih.gov/mesh/D010146 https://id.nlm.nih.gov/mesh/D015203 https://id.nlm.nih.gov/mesh/D012878 |
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https://id.nlm.nih.gov/mesh/D002280 https://id.nlm.nih.gov/mesh/D010146 https://id.nlm.nih.gov/mesh/D015203 https://id.nlm.nih.gov/mesh/D012878 |
| description |
ABSTRACT: Numerous surgical and nonsurgical modalities are available to treat basal cell carcinoma (BCC), but their true effectiveness and safety is unknown. This article summarizes the evidence presented in a recent Cochrane review and aims to facilitate the interpretation of the review's findings for the Spanish and Latin American scientific communities. Much of the evidence the reviewers found came from single studies, preventing meta-analysis. Conventional surgical excision continues to be the most effective treatment for low-risk BCC. Most studies had small sample sizes, and some had problems with blinding, limitations which will have affected the assessment of subjective outcomes, such as pain and cosmetic results. The authors identified a lack of standardization in relation to recurrences and cosmetic outcomes that threatens not only the internal validity of the studies but also their external validity and reproducibility. |
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2023 |
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2023 |
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2024-11-10T21:52:48Z |
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Sanclemente G, Aguirre DC, Thomson J. Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings. Actas Dermosifiliogr. 2023 Jan;114(1):39-48. English, Spanish. doi: 10.1016/j.ad.2022.06.021. |
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0001-7310 |
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https://hdl.handle.net/10495/43352 |
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10.1016/j.ad.2022.06.021 |
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1578-2190 |
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Sanclemente G, Aguirre DC, Thomson J. Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings. Actas Dermosifiliogr. 2023 Jan;114(1):39-48. English, Spanish. doi: 10.1016/j.ad.2022.06.021. 0001-7310 10.1016/j.ad.2022.06.021 1578-2190 |
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Actas Dermo-Sifiliogr. |
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10 páginas |
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Academia Española de Dermatología y Venereología |
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Aguirre Acevedo, Daniel CamiloSanclemente Mesa, GloriaThomson, JasonGRID - Grupo de Investigación Dermatológica2024-11-10T21:52:48Z2024-11-10T21:52:48Z2023Sanclemente G, Aguirre DC, Thomson J. Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of Findings. Actas Dermosifiliogr. 2023 Jan;114(1):39-48. English, Spanish. doi: 10.1016/j.ad.2022.06.021.0001-7310https://hdl.handle.net/10495/4335210.1016/j.ad.2022.06.0211578-2190ABSTRACT: Numerous surgical and nonsurgical modalities are available to treat basal cell carcinoma (BCC), but their true effectiveness and safety is unknown. This article summarizes the evidence presented in a recent Cochrane review and aims to facilitate the interpretation of the review's findings for the Spanish and Latin American scientific communities. Much of the evidence the reviewers found came from single studies, preventing meta-analysis. Conventional surgical excision continues to be the most effective treatment for low-risk BCC. Most studies had small sample sizes, and some had problems with blinding, limitations which will have affected the assessment of subjective outcomes, such as pain and cosmetic results. The authors identified a lack of standardization in relation to recurrences and cosmetic outcomes that threatens not only the internal validity of the studies but also their external validity and reproducibility.RESUMEN: Existen numerosas modalidades de tratamiento para el manejo de los carcinomas basocelulares (CBC), pero se desconoce la real eficacia y seguridad entre las alternativas quirúrgicas y no quirúrgicas disponibles. Este artículo resume la evidencia encontrada en la reciente revisión Cochrane de Thomson et al. y facilita la interpretación de sus resultados entre la comunidad científica iberolatinoamericana. La gran mayoría de la evidencia evaluada proviene de estudios individuales que impidieron la realización de una revisión sistemática cuantitativa. La escisión quirúrgica convencional continúa siendo la terapia más eficaz para el tratamiento de los CBC de bajo riesgo. La mayoría de estudios incluyeron tamanos ˜ de muestra pequenos ˜ y algunos tuvieron problemas con el cegamiento, lo que influiría en resultados subjetivos tales como el dolor o la cosmesis. Existe una falta de estandarización en relación con los desenlaces de recurrencia y de resultados cosméticos, lo que en conjunto afecta no solo la validez interna sino también la validez externa y la reproducibilidad de los estudios.COL005083910 páginasapplication/pdfengAcademia Española de Dermatología y VenereologíaMadrird, Españahttps://creativecommons.org/licenses/by-nc-nd/4.0/An error occurred getting the license - uri.info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Interventions for Basal Cell Carcinoma: Summary of Main Comparisons From a Cochrane Review and a Practical Interpretation of FindingsIntervenciones para el carcinoma basocelular cutáneo (revisión Cochrane): Resumen de las principales comparaciones e interpretación práctica de los resultadosArtículo de revisiónhttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionCarcinoma BasocelularCarcinoma, Basal CellDolorPainReproducibilidad de los ResultadosReproducibility of ResultsNeoplasias CutáneasSkin Neoplasmshttps://id.nlm.nih.gov/mesh/D002280https://id.nlm.nih.gov/mesh/D010146https://id.nlm.nih.gov/mesh/D015203https://id.nlm.nih.gov/mesh/D012878Actas Dermo-Sifiliogr.48139114Actas Dermo-SifiliográficasPublicationORIGINALSanclementeGloria_2023_Interventions_Basal_Cell_Carcinoma.pdfSanclementeGloria_2023_Interventions_Basal_Cell_Carcinoma.pdfArtículo de revisiónapplication/pdf1221069https://bibliotecadigital.udea.edu.co/bitstreams/fd466d85-567c-44e1-ba08-64b0f8e79d6b/download1ebd710d1b8a64045cfc7c04c7e530f2MD51trueAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; 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