Synthesis and cytotoxic activity of tri-acyl ester derivatives of uridine in breast cancer cells

ABSTRACT: Synthesize tri-acyl ester derivatives of uridine, and evaluate its cytotoxicity against breast cancer cells line. Methods: The tri-esterified uridine derivatives were obtained through Steglich esterification reaction by fatty and aromatic acids, and with acetic anhydride. An acetonide deri...

Full description

Autores:

Berrío Escobar, Jhon Fernando
Arango Carmona, Victor Hugo
Galeano Jaramillo, Elkin de Jesús
Márquez Fernández, Diana Margarita
Márquez Fernández, Maria Elena
Camargo Guerrero, Mauricio
Martínez Martínez, Alejandro

Tipo de recurso:

Article of investigation

Fecha de publicación:

2016

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/13078

Acceso en línea:

http://hdl.handle.net/10495/13078
http://dx.doi.org/10.4321/S2340-98942016000400005

Palabra clave:

Nucleósidos
Nucleosides
Neoplasias de la Mama
Breast Neoplasms
Actividad citotóxica
Cáncer de mama
Derivados de uridina

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-sa/4.0/