Historical trends in mortality from “older” vaccine-preventable diseases, Colombia: implications for elimination and control

Objective: This study aimed to describe the trends in mortality from eight vaccine-preventable diseases in Colombia in the last 40 years and their relationship with vaccination coverage. Study design: It is a population-based descriptive study. Methods: The frequencies of deaths by decade, disease, sex, and the specific mortality rates by age group were calculated. Using a negative binomial regression model, the 10-year changes in mortality and their relationship with vaccination coverage were determined. Results: The number of deaths and the adjusted rates decreased since 1989 in all diseases (incidence rate ratio <1 when compared with the 1979e1988 decade). Vaccination coverage below 90% is associated with an increase in mortality from diphtheria, measles, mumps, neonatal tetanus, and pertussis. Conclusion: Historical changes in mortality support the benefits of vaccination, but new efforts are required to sustain the elimination of diseases.

• Autores: Arango Úsuga, Carlos Andrés; Ochoa Acosta, Jesús Ernesto; Hincapié Palacio, Doracelly; León Álvarez, Alba Luz
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2022
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/46314
• Acceso en línea: https://hdl.handle.net/10495/46314
• Palabra clave: Enfermedades Prevenibles por Vacunación; Vaccine-Preventable Diseases; Cobertura de Vacunación; Vaccination Coverage; Mortalidad; Mortality; Estudios Retrospectivos; Retrospective Studies; Colombia - epidemiología; Colombia - epidemiology; Recién Nacido; Infant, Newborn; https://id.nlm.nih.gov/mesh/D000079263; https://id.nlm.nih.gov/mesh/D000073887; https://id.nlm.nih.gov/mesh/D009026; https://id.nlm.nih.gov/mesh/D012189; https://id.nlm.nih.gov/mesh/D003105; https://id.nlm.nih.gov/mesh/D007231; ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc-nd/4.0/