Stable extracellular RNA fragments of Mycobacterium tuberculosis induce early apoptosis in human monocytes via a caspase-8 dependent mechanism

ABSTRACT: The molecular basis of pathogen-induced host cell apoptosis is well characterized for a number of microorganisms. Mycobacterium tuberculosis is known to induce apoptosis and it was shown that live but not heat killed M. tuberculosis stimulates this biological pathway in monocytes. The depe...

Full description

Autores:

Obregón Henao, Andrés
Duque Correa, María Adelaida
Rojas López, Mauricio
García Moreno, Luis Fernando
Ortiz Reyes, Blanca Lucía
Brennan, Patrick J.
Belisle, John T

Tipo de recurso:

Article of investigation

Fecha de publicación:

2012

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39790

Acceso en línea:

https://hdl.handle.net/10495/39790

Palabra clave:

Apoptosis
Caspasa 8
Cromatografía de Afinidad
Chromatography, Affinity
Concanavalina A
Concanavalin A
Espacio Extracelular
Extracellular Space
Cinética
Kinetics
Monocitos
Monocytes
Mycobacterium tuberculosis
ARN Bacteriano
RNA, Bacterial
Sefarosa
Sepharose
Tuberculosis
Factor de Necrosis Tumoral alfa
Tumor Necrosis Factor-alpha
https://id.nlm.nih.gov/mesh/D017209
https://id.nlm.nih.gov/mesh/D053181
https://id.nlm.nih.gov/mesh/D002846
https://id.nlm.nih.gov/mesh/D003208
https://id.nlm.nih.gov/mesh/D005110
https://id.nlm.nih.gov/mesh/D007700
https://id.nlm.nih.gov/mesh/D009000
https://id.nlm.nih.gov/mesh/D009169
https://id.nlm.nih.gov/mesh/D012329
https://id.nlm.nih.gov/mesh/D012685
https://id.nlm.nih.gov/mesh/D014376
https://id.nlm.nih.gov/mesh/D014409

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/