A new pharmacodynamic approach to study antibiotic combinations against enterococci in vivo: Application to ampicillin plus ceftriaxone

ABSTRACT: The combination of ampicillin (AMP) and ceftriaxone (CRO) is considered synergistic against Enterococcus faecalis based on in vitro tests and the rabbit endocarditis model, however, in vitro assays are limited by the use of fixed antibiotic concentrations and the rabbit model by poor bacte...

Full description

Autores:

Jiménez Toro, Ivone Eliana
Rodríguez Jaramillo, Carlos Andrés
Zuluaga Salazar, Andrés Felipe
Vesga Meneses, Omar

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43307

Acceso en línea:

https://hdl.handle.net/10495/43307

Palabra clave:

Ampicilina
Ampicillin
Ceftriaxona
Ceftriaxone
Quimioterapia
Drug Therapy
Endocarditis
Enterococcus faecalis
Infecciones por Bacterias Grampositivas
Gram-Positive Bacterial Infections
Modelos Animales de Enfermedad
Disease Models, Animal
Quimioterapia Combinada
Drug Therapy, Combination
Endocarditis Bacteriana
Endocarditis, Bacterial
https://id.nlm.nih.gov/mesh/D000667
https://id.nlm.nih.gov/mesh/D002443
https://id.nlm.nih.gov/mesh/D004358
https://id.nlm.nih.gov/mesh/D004696
https://id.nlm.nih.gov/mesh/D013293
https://id.nlm.nih.gov/mesh/D016908
https://id.nlm.nih.gov/mesh/D004195
https://id.nlm.nih.gov/mesh/D004359
https://id.nlm.nih.gov/mesh/D004697

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/