Genetic diversity of hepatitis C virus and resistance associated substitutions to direct-acting antiviral treatment in Colombia

ABSTRACT: Hepatitis C virus (HCV) infection is one of the leading risk factors for end-stage liver disease development worldwide. This RNA virus displays high genetic diversity with 8 genotypes and 96 subgenotypes with heterogeneous geographical distribution around the world. In this study, we carri...

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Autores:

López Osorio, María Camila
Hoyos Duque, Sergio Iván
Restrepo Gutiérrez, Juan Carlos
Navas Navas, María Cristina
Usme Ciro, José Aldemar
Martínez, José William
Peláez Carvajal, Dioselina
Hernández, Javier

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39793

Acceso en línea:

https://hdl.handle.net/10495/39793

Palabra clave:

Antivirales - Farmacología
Antiviral Agents - Pharmacology
Colombia - Epidemiología
Colombia - Epidemiology
Farmacorresistencia Viral
Drug Resistance, Viral
Enfermedad Hepática en Estado Terminal
End Stage Liver Disease
Hepacivirus
Hepatitis C
Funciones de Verosimilitud
Likelihood Functions
Mutación Missense
Mutation, Missense
Filogenia
Phylogeny
Seroepidemiologic Studies
Proteínas no Estructurales Virales
Viral Nonstructural Proteins
Estudios Seroepidemiológicos
Hepatitis C Crónica
Hepatitis C, Chronic
https://id.nlm.nih.gov/mesh/D000998
https://id.nlm.nih.gov/mesh/D003105
https://id.nlm.nih.gov/mesh/D024882
https://id.nlm.nih.gov/mesh/D058625
https://id.nlm.nih.gov/mesh/D016174
https://id.nlm.nih.gov/mesh/D006526
https://id.nlm.nih.gov/mesh/D016013
https://id.nlm.nih.gov/mesh/D020125
https://id.nlm.nih.gov/mesh/D010802
https://id.nlm.nih.gov/mesh/D016036
https://id.nlm.nih.gov/mesh/D017361
https://id.nlm.nih.gov/mesh/D019698

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/