Management of CRSwNP in Latin America: A multidisciplinary consensus from an expert working group
ABSTRACT: Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition of the nasal and paranasal tissues, characterized by the presence of bilateral nasal polyps. While etiology and pathogenetic mechanisms are heterogeneous and complex, in most patients, disease is mediated predom...
- Autores:
-
Bedoya Gutiérrez, Juan David
Maspero, Jorge
Anselmo Lima, Wilma
Jimenez Chobillón, Marcos Alejandro
Ospina, Javier
Roithmann, Renato
Sadek Gonzalez, Andrés
Silva Rueda, Ricardo
- Tipo de recurso:
- Review article
- Fecha de publicación:
- 2024
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/45394
- Acceso en línea:
- https://hdl.handle.net/10495/45394
- Palabra clave:
- Productos Biológicos
Biological Products
Rinosinusitis
Rhinosinusitis
https://id.nlm.nih.gov/mesh/D001688
https://id.nlm.nih.gov/mesh/D000096825
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/
| Summary: | ABSTRACT: Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition of the nasal and paranasal tissues, characterized by the presence of bilateral nasal polyps. While etiology and pathogenetic mechanisms are heterogeneous and complex, in most patients, disease is mediated predominantly through type 2 inflammatory processes. Clinical management is challenging, and a multidisciplinary approach is preferred. Principal treatment approaches are the use of local/systemic corticosteroids and sinonasal surgery, although outcomes can be unsatisfactory. Recent availability of biological therapies targeting underlying inflammatory processes can offer effective treatment options in uncontrolled disease. Specialist guidelines greatly assist clinical decision-making, although as these are chiefly written from a global/international perspective, they may not wholly accommodate disease patterns and clinical practice at a regional level. An expert panel of specialists from Latin America was convened to develop regional guidance on the management of CRSwNP through a consensus approach. The present article presents the chief observations and recommendations which can provide guidance for clinicians in the Latin American region. |
|---|