Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome
Las enfermedades cardiovasculares constituyen la principal causa de morbilidad y mortalidad en todo el mundo. Dentro de este grupo, la enfermedad coronaria, junto con los accidentes cerebrovasculares, se destaca como la responsable de un elevado número de fallecimientos anuales, especialmente en adu...
- Autores:
-
Molano Arteaga, Andrés Felipe
Montoya Jaramillo, Susana
Tolosa Ramírez, Laura
Hincapié Isaza, Mateo
Dallos Ferrerosa, Juan Nicolás
- Tipo de recurso:
- Fecha de publicación:
- 2025
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- spa
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/48097
- Acceso en línea:
- https://hdl.handle.net/10495/48097
- Palabra clave:
- Enfermedades Cardiovasculares
Cardiopatías
Isquemia Miocárdica
Enfermedad Coronaria
Cardiovascular Diseases
Heart Diseases
Myocardial Ischemia
Coronary Disease
https://id.nlm.nih.gov/mesh/D003327
https://id.nlm.nih.gov/mesh/D017202
https://id.nlm.nih.gov/mesh/D006331
https://id.nlm.nih.gov/mesh/D002318
ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-sa/4.0/
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome |
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome |
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome Enfermedades Cardiovasculares Cardiopatías Isquemia Miocárdica Enfermedad Coronaria Cardiovascular Diseases Heart Diseases Myocardial Ischemia Coronary Disease https://id.nlm.nih.gov/mesh/D003327 https://id.nlm.nih.gov/mesh/D017202 https://id.nlm.nih.gov/mesh/D006331 https://id.nlm.nih.gov/mesh/D002318 ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades |
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome |
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome |
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome |
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome |
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Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome |
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Molano Arteaga, Andrés Felipe Montoya Jaramillo, Susana Tolosa Ramírez, Laura Hincapié Isaza, Mateo Dallos Ferrerosa, Juan Nicolás |
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Molano Arteaga, Andrés Felipe Montoya Jaramillo, Susana Tolosa Ramírez, Laura Hincapié Isaza, Mateo Dallos Ferrerosa, Juan Nicolás |
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Enfermedades Cardiovasculares Cardiopatías Isquemia Miocárdica Enfermedad Coronaria Cardiovascular Diseases Heart Diseases Myocardial Ischemia Coronary Disease |
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Enfermedades Cardiovasculares Cardiopatías Isquemia Miocárdica Enfermedad Coronaria Cardiovascular Diseases Heart Diseases Myocardial Ischemia Coronary Disease https://id.nlm.nih.gov/mesh/D003327 https://id.nlm.nih.gov/mesh/D017202 https://id.nlm.nih.gov/mesh/D006331 https://id.nlm.nih.gov/mesh/D002318 ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades |
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https://id.nlm.nih.gov/mesh/D003327 https://id.nlm.nih.gov/mesh/D017202 https://id.nlm.nih.gov/mesh/D006331 https://id.nlm.nih.gov/mesh/D002318 |
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ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades |
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Las enfermedades cardiovasculares constituyen la principal causa de morbilidad y mortalidad en todo el mundo. Dentro de este grupo, la enfermedad coronaria, junto con los accidentes cerebrovasculares, se destaca como la responsable de un elevado número de fallecimientos anuales, especialmente en adultos y personas mayores de 65 años. En este contexto, comprender a fondo, diagnosticar de manera precoz y gestionar de forma adecuada y oportuna estas condiciones adquiere una importancia crucial. El SCA, que abarca un espectro de enfermedades, se caracteriza por la interrupción del flujo sanguíneo hacia el músculo cardíaco e incluye la angina inestable y el infarto agudo de miocardio, este último de acuerdo con los hallazgos electrocardiográficos se puede clasificar en: infarto agudo de miocardio con elevación del segmento ST o infarto agudo de miocardio sin elevación del segmento ST. Clínicamente, este síndrome se manifiesta a través de una variedad de signos y síntomas, lo que requiere una atención precisa y diferenciada para un manejo efectivo. |
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2025 |
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2025-11-03T15:22:13Z |
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2025 |
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Molano AF, Montoya S, Tolosa L, Hincapié M, Dallos JN. Actualización – 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome. [Internet]. Medellín: Perlas Clínicas, Facultad de Medicina, Universidad de Antioquia; 2023 [acceso día de mes de año]. DOI: https://doi.org/10.59473/medudea.pc.2023.62 |
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https://hdl.handle.net/10495/48097 |
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10.59473/medudea.pc.2023.62 |
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Molano AF, Montoya S, Tolosa L, Hincapié M, Dallos JN. Actualización – 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome. [Internet]. Medellín: Perlas Clínicas, Facultad de Medicina, Universidad de Antioquia; 2023 [acceso día de mes de año]. DOI: https://doi.org/10.59473/medudea.pc.2023.62 10.59473/medudea.pc.2023.62 |
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SCA 2023 NUEVAS RECOMENDACIONES – Urgencias y Emergencias [Internet]. [cited 2023 Nov 5]. Available from: https://www.urgenciasyemergen.com/sdm_downloads/sca-2023-nuevas-recomendaciones/ Gaviria S, Ramírez A, Alzate M, Contreras H, Jaramillo N, Muñoz MC. Epidemiología del síndrome coronario agudo. Medicina UPB [Internet]. 2020 Feb 15 [cited 2023 Nov 5];39(1):49–56. Available from: https://revistas.upb.edu.co/index.php/medicina/article/view/406 Infarto agudo de miocardio en Colombia (2011 – 2021), un estudio de carga de la enfermedad [Internet]. [cited 2023 Nov 5]. Available from: https://repositorio.unbosque.edu.co/handle/20.500.12495/9891 Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, et al. 2023 ESC Guidelines for the management of acute coronary syndromes: Developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC). Eur Heart J [Internet]. 2023 Oct 12 [cited 2023 Nov 5];44(38):3720–826. Available from: https://dx.doi.org/10.1093/eurheartj/ehad191 Eagle KA, Lim MJ, Dabbous OH, Pieper KS, Goldberg RJ, Van De Werf F, et al. A Validated Prediction Model for All Forms of Acute Coronary Syndrome: Estimating the Risk of 6-Month Postdischarge Death in an International Registry. JAMA [Internet]. 2004 Jun 9 [cited 2023 Nov 5];291(22):2727–33. Available from: https://jamanetwork-https://jamanetwork-com.udea.lookproxy.com/journals/jama/fullarticle/198895com.udea.lookproxy.com/journals/jama/fullarticle/198895 GraceScore [Internet]. [cited 2023 Nov 5]. Available from: https://www.outcomes-umassmed.org/grace/acs_risk2/index.html Escala ARC-HBR [Internet]. [cited 2023 Nov 5]. Available from: https://www.rccc.eu/Indica/ARC-HBR.html Clinical Frailty Scale – Geriatric Medicine Research – Dalhousie University [Internet]. [cited 2023 Nov 5]. Available from: https://www.dal.ca/sites/gmr/our-tools/clinical-frailty-scale.html Indice de Comorbilidad de Charlson (CCI) | SAMIUC [Internet]. [cited 2023 Nov 5]. Available from: https://www.samiuc.es/indice-de-comorbilidad-de-charlson-cci/ |
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Molano Arteaga, Andrés FelipeMontoya Jaramillo, SusanaTolosa Ramírez, LauraHincapié Isaza, MateoDallos Ferrerosa, Juan Nicolás2025-11-03T15:22:13Z2025Molano AF, Montoya S, Tolosa L, Hincapié M, Dallos JN. Actualización – 2023 European Society of Cardiology Guidelines for the management of acute coronary syndrome. [Internet]. Medellín: Perlas Clínicas, Facultad de Medicina, Universidad de Antioquia; 2023 [acceso día de mes de año]. DOI: https://doi.org/10.59473/medudea.pc.2023.62https://hdl.handle.net/10495/4809710.59473/medudea.pc.2023.62Las enfermedades cardiovasculares constituyen la principal causa de morbilidad y mortalidad en todo el mundo. Dentro de este grupo, la enfermedad coronaria, junto con los accidentes cerebrovasculares, se destaca como la responsable de un elevado número de fallecimientos anuales, especialmente en adultos y personas mayores de 65 años. En este contexto, comprender a fondo, diagnosticar de manera precoz y gestionar de forma adecuada y oportuna estas condiciones adquiere una importancia crucial. El SCA, que abarca un espectro de enfermedades, se caracteriza por la interrupción del flujo sanguíneo hacia el músculo cardíaco e incluye la angina inestable y el infarto agudo de miocardio, este último de acuerdo con los hallazgos electrocardiográficos se puede clasificar en: infarto agudo de miocardio con elevación del segmento ST o infarto agudo de miocardio sin elevación del segmento ST. Clínicamente, este síndrome se manifiesta a través de una variedad de signos y síntomas, lo que requiere una atención precisa y diferenciada para un manejo efectivo.50 páginasapplication/pdfspaUniversidad de Antioquia, Facultad de MedicinaMedellín, Colombiahttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessAttribution-NonCommercial-ShareAlike 4.0 Internationalhttp://purl.org/coar/access_right/c_abf2Actualización - 2023 European Society of Cardiology Guidelines for the management of acute coronary syndromeArtículo de revistahttp://purl.org/coar/resource_type/c_3e5ahttps://purl.org/redcol/resource_type/GCTexthttp://purl.org/coar/version/c_b1a7d7d4d402bcceinfo:eu-repo/semantics/contributionToPeriodicalinfo:eu-repo/semantics/draftSCA 2023 NUEVAS RECOMENDACIONES – Urgencias y Emergencias [Internet]. [cited 2023 Nov 5]. Available from: https://www.urgenciasyemergen.com/sdm_downloads/sca-2023-nuevas-recomendaciones/Gaviria S, Ramírez A, Alzate M, Contreras H, Jaramillo N, Muñoz MC. Epidemiología del síndrome coronario agudo. Medicina UPB [Internet]. 2020 Feb 15 [cited 2023 Nov 5];39(1):49–56. Available from: https://revistas.upb.edu.co/index.php/medicina/article/view/406Infarto agudo de miocardio en Colombia (2011 – 2021), un estudio de carga de la enfermedad [Internet]. [cited 2023 Nov 5]. Available from: https://repositorio.unbosque.edu.co/handle/20.500.12495/9891Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, et al. 2023 ESC Guidelines for the management of acute coronary syndromes: Developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC). Eur Heart J [Internet]. 2023 Oct 12 [cited 2023 Nov 5];44(38):3720–826. Available from: https://dx.doi.org/10.1093/eurheartj/ehad191Eagle KA, Lim MJ, Dabbous OH, Pieper KS, Goldberg RJ, Van De Werf F, et al. A Validated Prediction Model for All Forms of Acute Coronary Syndrome: Estimating the Risk of 6-Month Postdischarge Death in an International Registry. JAMA [Internet]. 2004 Jun 9 [cited 2023 Nov 5];291(22):2727–33. Available from: https://jamanetwork-https://jamanetwork-com.udea.lookproxy.com/journals/jama/fullarticle/198895com.udea.lookproxy.com/journals/jama/fullarticle/198895GraceScore [Internet]. [cited 2023 Nov 5]. Available from: https://www.outcomes-umassmed.org/grace/acs_risk2/index.htmlEscala ARC-HBR [Internet]. [cited 2023 Nov 5]. Available from: https://www.rccc.eu/Indica/ARC-HBR.htmlClinical Frailty Scale – Geriatric Medicine Research – Dalhousie University [Internet]. [cited 2023 Nov 5]. Available from: https://www.dal.ca/sites/gmr/our-tools/clinical-frailty-scale.htmlIndice de Comorbilidad de Charlson (CCI) | SAMIUC [Internet]. [cited 2023 Nov 5]. Available from: https://www.samiuc.es/indice-de-comorbilidad-de-charlson-cci/Perlas clínicasEnfermedades CardiovascularesCardiopatíasIsquemia MiocárdicaEnfermedad CoronariaCardiovascular DiseasesHeart DiseasesMyocardial IschemiaCoronary Diseasehttps://id.nlm.nih.gov/mesh/D003327https://id.nlm.nih.gov/mesh/D017202https://id.nlm.nih.gov/mesh/D006331https://id.nlm.nih.gov/mesh/D002318ODS 3: Salud y bienestar. 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