Effect of the variation in the extracellular concentration of l-arginine in the physiology of Leishmania (Viannia) braziliensis and its susceptibility to some antileishmanial drugs

ABSTRACT: The knowledge about amino acid metabolism in trypanosomatids is a valuable source of new therapeutic targets. l-arginine is an essential amino acid for Leishmania parasites, and it participates in the synthesis of polyamines, a group of essential nutrients used for nucleic acids, proteins...

Full description

Autores:

Robledo Restrepo, Sara María
Giraldo Hincapié, Manuela
Upegui Zapata, Yulieth Alexandra
Higuita Castro, Jorge Luis
Gutiérrez Guarnizo, Sneider Alexander
Pulido Muñoz, Sergio Andrés
González López, Luis Alberto

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39035

Acceso en línea:

https://hdl.handle.net/10495/39035

Palabra clave:

Arginina
Arginine
Leishmania braziliensis
Leishmania
Ratones Endogámicos BALB C
Mice, Inbred BALB C
Ácidos Nucleicos
Nucleic Acids
Poliaminas
Polyamines
Especies Reactivas de Oxígeno
Reactive Oxygen Species
https://id.nlm.nih.gov/mesh/D007891
https://id.nlm.nih.gov/mesh/D017382
https://id.nlm.nih.gov/mesh/D001120
https://id.nlm.nih.gov/mesh/D007892
https://id.nlm.nih.gov/mesh/D008807
https://id.nlm.nih.gov/mesh/D009696
https://id.nlm.nih.gov/mesh/D011073

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/