Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives
ABSTRACT: The parasite resistance and side effects of drugs used to treat protozoal diseases have led to the search for new therapies, both natural and synthetic. Studies have shown that various α,β-unsaturated δlactones displayed high antiprotozoal activity and thus are promising compounds for new...
- Autores:
-
Cardona Galeano, Wilson
Saez Vega, Jairo Antonio
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2011
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/30994
- Acceso en línea:
- https://hdl.handle.net/10495/30994
https://www.ajol.info/index.php/tjpr/article/view/71710
- Palabra clave:
- Lactonas
Lactones
Pironas
Pyrones
Antiparasitarios
Antiparasitic Agents
Antiprotozoarios
Leishmania
Malaria
Enfermedad de chagas
Chagas Disease
Plasmodium falciparum
Tripanosoma cruzi
https://id.nlm.nih.gov/mesh/D007783
https://id.nlm.nih.gov/mesh/D011753
https://id.nlm.nih.gov/mesh/D000977
Antiprotozoal Agents
https://id.nlm.nih.gov/mesh/D000981
https://id.nlm.nih.gov/mesh/D007891
https://id.nlm.nih.gov/mesh/D008288
https://id.nlm.nih.gov/mesh/D014355
http://aims.fao.org/aos/agrovoc/c_31217
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by/4.0/
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| dc.title.spa.fl_str_mv |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives |
| title |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives |
| spellingShingle |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives Lactonas Lactones Pironas Pyrones Antiparasitarios Antiparasitic Agents Antiprotozoarios Leishmania Malaria Enfermedad de chagas Chagas Disease Plasmodium falciparum Tripanosoma cruzi https://id.nlm.nih.gov/mesh/D007783 https://id.nlm.nih.gov/mesh/D011753 https://id.nlm.nih.gov/mesh/D000977 Antiprotozoal Agents https://id.nlm.nih.gov/mesh/D000981 https://id.nlm.nih.gov/mesh/D007891 https://id.nlm.nih.gov/mesh/D008288 https://id.nlm.nih.gov/mesh/D014355 http://aims.fao.org/aos/agrovoc/c_31217 |
| title_short |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives |
| title_full |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives |
| title_fullStr |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives |
| title_full_unstemmed |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives |
| title_sort |
Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives |
| dc.creator.fl_str_mv |
Cardona Galeano, Wilson Saez Vega, Jairo Antonio |
| dc.contributor.author.none.fl_str_mv |
Cardona Galeano, Wilson Saez Vega, Jairo Antonio |
| dc.contributor.researchgroup.spa.fl_str_mv |
Química de Plantas Colombianas |
| dc.subject.decs.none.fl_str_mv |
Lactonas Lactones Pironas Pyrones Antiparasitarios Antiparasitic Agents Antiprotozoarios Leishmania Malaria Enfermedad de chagas Chagas Disease |
| topic |
Lactonas Lactones Pironas Pyrones Antiparasitarios Antiparasitic Agents Antiprotozoarios Leishmania Malaria Enfermedad de chagas Chagas Disease Plasmodium falciparum Tripanosoma cruzi https://id.nlm.nih.gov/mesh/D007783 https://id.nlm.nih.gov/mesh/D011753 https://id.nlm.nih.gov/mesh/D000977 Antiprotozoal Agents https://id.nlm.nih.gov/mesh/D000981 https://id.nlm.nih.gov/mesh/D007891 https://id.nlm.nih.gov/mesh/D008288 https://id.nlm.nih.gov/mesh/D014355 http://aims.fao.org/aos/agrovoc/c_31217 |
| dc.subject.agrovoc.none.fl_str_mv |
Plasmodium falciparum |
| dc.subject.proposal.none.fl_str_mv |
Tripanosoma cruzi |
| dc.subject.meshuri.none.fl_str_mv |
https://id.nlm.nih.gov/mesh/D007783 https://id.nlm.nih.gov/mesh/D011753 https://id.nlm.nih.gov/mesh/D000977 Antiprotozoal Agents https://id.nlm.nih.gov/mesh/D000981 https://id.nlm.nih.gov/mesh/D007891 https://id.nlm.nih.gov/mesh/D008288 https://id.nlm.nih.gov/mesh/D014355 http://aims.fao.org/aos/agrovoc/c_31217 |
| description |
ABSTRACT: The parasite resistance and side effects of drugs used to treat protozoal diseases have led to the search for new therapies, both natural and synthetic. Studies have shown that various α,β-unsaturated δlactones displayed high antiprotozoal activity and thus are promising compounds for new drug discovery and development. These compounds and their activity are examined in this review. |
| publishDate |
2011 |
| dc.date.issued.none.fl_str_mv |
2011 |
| dc.date.accessioned.none.fl_str_mv |
2022-09-30T17:36:31Z |
| dc.date.available.none.fl_str_mv |
2022-09-30T17:36:31Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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https://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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publishedVersion |
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1596-5996 |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/30994 |
| dc.identifier.doi.none.fl_str_mv |
10.4314/tjpr.v10i5.17 |
| dc.identifier.eissn.none.fl_str_mv |
1596-9827 |
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https://www.ajol.info/index.php/tjpr/article/view/71710 |
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1596-5996 10.4314/tjpr.v10i5.17 1596-9827 |
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https://hdl.handle.net/10495/30994 https://www.ajol.info/index.php/tjpr/article/view/71710 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Trop. J. Pharm. Res |
| dc.relation.citationendpage.spa.fl_str_mv |
680 |
| dc.relation.citationissue.spa.fl_str_mv |
5 |
| dc.relation.citationstartpage.spa.fl_str_mv |
671 |
| dc.relation.citationvolume.spa.fl_str_mv |
10 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Tropical Journal of Pharmaceutical |
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https://creativecommons.org/licenses/by/4.0/ |
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http://creativecommons.org/licenses/by/2.5/co/ |
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| dc.publisher.spa.fl_str_mv |
University of Benin, Faculty of Pharmacy |
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Ciudad de Benín, Nigeria |
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Universidad de Antioquia |
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Cardona Galeano, WilsonSaez Vega, Jairo AntonioQuímica de Plantas Colombianas2022-09-30T17:36:31Z2022-09-30T17:36:31Z20111596-5996https://hdl.handle.net/10495/3099410.4314/tjpr.v10i5.171596-9827https://www.ajol.info/index.php/tjpr/article/view/71710ABSTRACT: The parasite resistance and side effects of drugs used to treat protozoal diseases have led to the search for new therapies, both natural and synthetic. Studies have shown that various α,β-unsaturated δlactones displayed high antiprotozoal activity and thus are promising compounds for new drug discovery and development. These compounds and their activity are examined in this review.COL001532910application/pdfengUniversity of Benin, Faculty of PharmacyCiudad de Benín, Nigeriahttps://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic AlternativesArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionLactonasLactonesPironasPyronesAntiparasitariosAntiparasitic AgentsAntiprotozoariosLeishmaniaMalariaEnfermedad de chagasChagas DiseasePlasmodium falciparumTripanosoma cruzihttps://id.nlm.nih.gov/mesh/D007783https://id.nlm.nih.gov/mesh/D011753https://id.nlm.nih.gov/mesh/D000977Antiprotozoal Agentshttps://id.nlm.nih.gov/mesh/D000981https://id.nlm.nih.gov/mesh/D007891https://id.nlm.nih.gov/mesh/D008288https://id.nlm.nih.gov/mesh/D014355http://aims.fao.org/aos/agrovoc/c_31217Trop. J. Pharm. 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