Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia
ABSTRACT : OBJECTIVE: To determine the seroprevalence of markers of transfusion transmissible infections in donors of a blood bank in Medellin, Colombia, beteween 2007 and 2010. METHODS: A cross-sectional secondary data source, based on the results of biological testing of donors to a blood bank in...
- Autores:
-
Patiño Bedoya, Jair Alberto
Cortés Márquez, Mónica María
Cardona Arias, Jaiberth Antonio
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2012
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
spa
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/29395
- Acceso en línea:
- http://hdl.handle.net/10495/29395
- Palabra clave:
- Donantes de Sangre
Blood Donors
Trypanosoma cruzi
Treponema pallidum
Virus de la Hepatitis B
Hepatitis B virus
Hepacivirus
VIH
HIV
Estudios Seroepidemiológicos
Seroepidemiologic Studies
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
| id |
UDEA2_68de4abe7d649403e009b7e089031e93 |
|---|---|
| oai_identifier_str |
oai:bibliotecadigital.udea.edu.co:10495/29395 |
| network_acronym_str |
UDEA2 |
| network_name_str |
Repositorio UdeA |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia |
| dc.title.translated.spa.fl_str_mv |
Seroprevalence of markers of transfusion transmissible infections in blood bank in Colombia |
| title |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia |
| spellingShingle |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia Donantes de Sangre Blood Donors Trypanosoma cruzi Treponema pallidum Virus de la Hepatitis B Hepatitis B virus Hepacivirus VIH HIV Estudios Seroepidemiológicos Seroepidemiologic Studies |
| title_short |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia |
| title_full |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia |
| title_fullStr |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia |
| title_full_unstemmed |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia |
| title_sort |
Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de Colombia |
| dc.creator.fl_str_mv |
Patiño Bedoya, Jair Alberto Cortés Márquez, Mónica María Cardona Arias, Jaiberth Antonio |
| dc.contributor.author.none.fl_str_mv |
Patiño Bedoya, Jair Alberto Cortés Márquez, Mónica María Cardona Arias, Jaiberth Antonio |
| dc.contributor.researchgroup.spa.fl_str_mv |
Hematopatologia Molecular Salud y Sostenibilidad |
| dc.subject.decs.none.fl_str_mv |
Donantes de Sangre Blood Donors Trypanosoma cruzi Treponema pallidum Virus de la Hepatitis B Hepatitis B virus Hepacivirus VIH HIV Estudios Seroepidemiológicos Seroepidemiologic Studies |
| topic |
Donantes de Sangre Blood Donors Trypanosoma cruzi Treponema pallidum Virus de la Hepatitis B Hepatitis B virus Hepacivirus VIH HIV Estudios Seroepidemiológicos Seroepidemiologic Studies |
| description |
ABSTRACT : OBJECTIVE: To determine the seroprevalence of markers of transfusion transmissible infections in donors of a blood bank in Medellin, Colombia, beteween 2007 and 2010. METHODS: A cross-sectional secondary data source, based on the results of biological testing of donors to a blood bank in Medellin. We determined the seroprevalence of markers of infection and were compared by sex and type of donor through frequency analysis, chi square, Fisher and prevalence ratios. RESULTS: The base population was 65,535 donors, and 3.3% had at least one positive biological test. The most prevalent marker in the blood bank testing was syphilis (1.2%), followed by trypanosomiasis (1.0%), hepatitis C virus (HCV) (0.6%), human immunodefi ciency virus (HIV) 0.5% and hepatitis B virus (HBV) (0.2%). Based on the reference laboratory found a prevalence of 0.6% for syphilis, 0.1% for (HBV) and 0% for (HCV), (HIV) and Chagas. We found statistical differences in the prevalence of (HBV) and syphilis by sex and type of donor. CONCLUSIONS: The results are consistent with the prevalences given by Pan American Health Organization and can be correlated with the global prevalence of transfusion-transmitted infections. The results founds by the blood bank lead to a transfusion risk reduction but limit the optimization of resources by excluding donors classifi ed as false positives. |
| publishDate |
2012 |
| dc.date.issued.none.fl_str_mv |
2012 |
| dc.date.accessioned.none.fl_str_mv |
2022-06-23T23:53:58Z |
| dc.date.available.none.fl_str_mv |
2022-06-23T23:53:58Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
| dc.type.coarversion.spa.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| status_str |
publishedVersion |
| dc.identifier.issn.none.fl_str_mv |
0034-8910 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/29395 |
| dc.identifier.doi.none.fl_str_mv |
10.1590/S0034-89102012000600004 |
| dc.identifier.eissn.none.fl_str_mv |
1518-8787 |
| identifier_str_mv |
0034-8910 10.1590/S0034-89102012000600004 1518-8787 |
| url |
http://hdl.handle.net/10495/29395 |
| dc.language.iso.spa.fl_str_mv |
eng spa |
| language |
eng spa |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Rev. Saúde Pública. |
| dc.relation.citationendpage.spa.fl_str_mv |
959 |
| dc.relation.citationissue.spa.fl_str_mv |
6 |
| dc.relation.citationstartpage.spa.fl_str_mv |
950 |
| dc.relation.citationvolume.spa.fl_str_mv |
46 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Revista de Saúde Pública |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by/2.5/co/ |
| dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
| dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| rights_invalid_str_mv |
http://creativecommons.org/licenses/by/2.5/co/ https://creativecommons.org/licenses/by/4.0/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.extent.spa.fl_str_mv |
9 |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.spa.fl_str_mv |
Universidade de São Paulo, Faculdade de Saúde Pública |
| dc.publisher.place.spa.fl_str_mv |
Sao Paulo, Brasil |
| institution |
Universidad de Antioquia |
| bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstreams/c43eae2c-496b-49a3-99cf-6dcab128bb6e/download https://bibliotecadigital.udea.edu.co/bitstreams/70c9c5bb-5e90-43b7-8a5c-3a917051af33/download https://bibliotecadigital.udea.edu.co/bitstreams/8cfb9229-1e77-4cd2-8819-ece1a34f736c/download https://bibliotecadigital.udea.edu.co/bitstreams/a9f7e73c-3e91-4905-b9e5-25ca8e93a968/download https://bibliotecadigital.udea.edu.co/bitstreams/db923b52-b95d-436a-b657-10be4e6bb1ad/download https://bibliotecadigital.udea.edu.co/bitstreams/8fcd1b22-7a9f-4c19-aaf6-6f2eb4117b54/download https://bibliotecadigital.udea.edu.co/bitstreams/f953fbef-2701-4978-8ff3-a9e914b44d7f/download https://bibliotecadigital.udea.edu.co/bitstreams/0bfc4d29-d1f0-428f-895d-d2a5566e5dcb/download |
| bitstream.checksum.fl_str_mv |
1646d1f6b96dbbbc38035efc9239ac9c 8a4605be74aa9ea9d79846c1fba20a33 b9ccb731c351dc2d204a0d2bd813045b 447ad4f64b4bfca0ac45a0e48f5faa6c e1ee36a571ab3747e8fb647f09bc0866 16fb6d622b904e3f1204b8bca78560a9 9ccd6436d833a7c45d056f40d71c4e25 36826e821fcda63134a8b0b3e537b04b |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional de la Universidad de Antioquia |
| repository.mail.fl_str_mv |
aplicacionbibliotecadigitalbiblioteca@udea.edu.co |
| _version_ |
1851052166744113152 |
| spelling |
Patiño Bedoya, Jair AlbertoCortés Márquez, Mónica MaríaCardona Arias, Jaiberth AntonioHematopatologia MolecularSalud y Sostenibilidad2022-06-23T23:53:58Z2022-06-23T23:53:58Z20120034-8910http://hdl.handle.net/10495/2939510.1590/S0034-891020120006000041518-8787ABSTRACT : OBJECTIVE: To determine the seroprevalence of markers of transfusion transmissible infections in donors of a blood bank in Medellin, Colombia, beteween 2007 and 2010. METHODS: A cross-sectional secondary data source, based on the results of biological testing of donors to a blood bank in Medellin. We determined the seroprevalence of markers of infection and were compared by sex and type of donor through frequency analysis, chi square, Fisher and prevalence ratios. RESULTS: The base population was 65,535 donors, and 3.3% had at least one positive biological test. The most prevalent marker in the blood bank testing was syphilis (1.2%), followed by trypanosomiasis (1.0%), hepatitis C virus (HCV) (0.6%), human immunodefi ciency virus (HIV) 0.5% and hepatitis B virus (HBV) (0.2%). Based on the reference laboratory found a prevalence of 0.6% for syphilis, 0.1% for (HBV) and 0% for (HCV), (HIV) and Chagas. We found statistical differences in the prevalence of (HBV) and syphilis by sex and type of donor. CONCLUSIONS: The results are consistent with the prevalences given by Pan American Health Organization and can be correlated with the global prevalence of transfusion-transmitted infections. The results founds by the blood bank lead to a transfusion risk reduction but limit the optimization of resources by excluding donors classifi ed as false positives.RESUMEN : OBJETIVO: Determinar la seroprevalencia de marcadores de infecciones transmisibles por vía transfusional. MÉTODOS: Estudio transversal con fuente de información secundaria, basada en los resultados de pruebas biológicas en los donantes de un banco de sangre de Medellín, Colombia, de 2007 a 2010. Se determinó la seroprevalencia de los marcadores de infección y se compararon según sexo y tipo de donante a través de análisis de frecuencias, chi cuadrado, Fisher y razones de prevalencia. RESULTADOS: La población de base estuvo conformada por 65.535 donantes de los cuales, 3,3% presentaran al menos una prueba biológica positiva. El marcador más prevalente en las pruebas del banco de sangre fue sífi lis (1,2%), seguido de tripanosomiasis (1,0%), virus de la hepatitis C (VHC) (0,6%), virus de la inmunodefi ciencia humana (VIH) (0,5%) y virus de la hepatitis B (VHB) (0,2%). Con base en el laboratorio de referencia se halló una prevalencia de 0,6% para sífi lis, 0,1% para VHB y 0% para VHC, VIH y Chagas. Se hallaron diferencias estadísticas en la prevalencia de VHB y sífi lis según sexo y tipo de donante. CONCLUSIONES: Los resultados son coherentes con las prevalencias dadas por la Organización Panamericana de la Salud (OPS) y se pueden correlacionar con la prevalencia mundial de las infecciones transmisibles por via transfusional. Los resultados hallados en las pruebas del banco de sangre posibilitan la disminución del riesgo transfusional pero limitan la optimización de recursos al excluir donantes clasifi cados como falsos positivos.COL0043226COL00888819application/pdfengspaUniversidade de São Paulo, Faculdade de Saúde PúblicaSao Paulo, Brasilhttp://creativecommons.org/licenses/by/2.5/co/https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Seroprevalencia de marcadores de infecciones transmisibles por vía transfusional en banco de sangre de ColombiaSeroprevalence of markers of transfusion transmissible infections in blood bank in ColombiaArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionDonantes de SangreBlood DonorsTrypanosoma cruziTreponema pallidumVirus de la Hepatitis BHepatitis B virusHepacivirusVIHHIVEstudios SeroepidemiológicosSeroepidemiologic StudiesRev. Saúde Pública.959695046Revista de Saúde PúblicaPublicationCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927https://bibliotecadigital.udea.edu.co/bitstreams/c43eae2c-496b-49a3-99cf-6dcab128bb6e/download1646d1f6b96dbbbc38035efc9239ac9cMD53falseAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/70c9c5bb-5e90-43b7-8a5c-3a917051af33/download8a4605be74aa9ea9d79846c1fba20a33MD54falseAnonymousREADORIGINALPatiñoJair_2012_Seroprevalence_Markers.pdfPatiñoJair_2012_Seroprevalence_Markers.pdfArtículo de investigaciónapplication/pdf57511https://bibliotecadigital.udea.edu.co/bitstreams/8cfb9229-1e77-4cd2-8819-ece1a34f736c/downloadb9ccb731c351dc2d204a0d2bd813045bMD51trueAnonymousREADPatiñoJair_2012_Seroprevalencia_Marcadores.pdfPatiñoJair_2012_Seroprevalencia_Marcadores.pdfArtículo de investigaciónapplication/pdf62617https://bibliotecadigital.udea.edu.co/bitstreams/a9f7e73c-3e91-4905-b9e5-25ca8e93a968/download447ad4f64b4bfca0ac45a0e48f5faa6cMD52falseAnonymousREADTEXTPatiñoJair_2012_Seroprevalence_Markers.pdf.txtPatiñoJair_2012_Seroprevalence_Markers.pdf.txtExtracted texttext/plain33054https://bibliotecadigital.udea.edu.co/bitstreams/db923b52-b95d-436a-b657-10be4e6bb1ad/downloade1ee36a571ab3747e8fb647f09bc0866MD59falseAnonymousREADPatiñoJair_2012_Seroprevalencia_Marcadores.pdf.txtPatiñoJair_2012_Seroprevalencia_Marcadores.pdf.txtExtracted texttext/plain37664https://bibliotecadigital.udea.edu.co/bitstreams/8fcd1b22-7a9f-4c19-aaf6-6f2eb4117b54/download16fb6d622b904e3f1204b8bca78560a9MD511falseAnonymousREADTHUMBNAILPatiñoJair_2012_Seroprevalence_Markers.pdf.jpgPatiñoJair_2012_Seroprevalence_Markers.pdf.jpgGenerated Thumbnailimage/jpeg10717https://bibliotecadigital.udea.edu.co/bitstreams/f953fbef-2701-4978-8ff3-a9e914b44d7f/download9ccd6436d833a7c45d056f40d71c4e25MD510falseAnonymousREADPatiñoJair_2012_Seroprevalencia_Marcadores.pdf.jpgPatiñoJair_2012_Seroprevalencia_Marcadores.pdf.jpgGenerated Thumbnailimage/jpeg12739https://bibliotecadigital.udea.edu.co/bitstreams/0bfc4d29-d1f0-428f-895d-d2a5566e5dcb/download36826e821fcda63134a8b0b3e537b04bMD512falseAnonymousREAD10495/29395oai:bibliotecadigital.udea.edu.co:10495/293952025-03-26 17:59:01.192http://creativecommons.org/licenses/by/2.5/co/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.coTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo= |